Advanced search
Publication Cover
Epigenetics Volume 15, 2020 - Issue 8
Submit an article Journal homepage
2,952
Views
31
CrossRef citations to date
0
Altmetric
Research Paper

CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain

Noemi Montia Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy;b Department of Surgery “P. Valdoni”, Sapienza University of Rome, Rome, ItalyView further author information
,
Rosaria A. Cavallarob Department of Surgery “P. Valdoni”, Sapienza University of Rome, Rome, ItalyView further author information
,
Andrea Stoccoroc Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, ItalyView further author information
,
Vincenzina Nicoliab Department of Surgery “P. Valdoni”, Sapienza University of Rome, Rome, ItalyView further author information
,
Sigfrido Scarpab Department of Surgery “P. Valdoni”, Sapienza University of Rome, Rome, ItalyView further author information
,
Gabor G. Kovacsd Institute of Neurology, Medical University of Vienna, Vienna, AustriaView further author information
,
Maria Teresa Fiorenzae Department of Psychology, Division of Neuroscience, Sapienza University of Rome, Rome, Italy;f IRCCS Fondazione Santa Lucia, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-5079-4019View further author information
ORCID Icon,
Marco Lucarellia Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy;g Pasteur Institute Cenci Bolognetti Foundation, Sapienza University of Rome, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-5538-2494View further author information
ORCID Icon,
Eleonora Aronicah Department of (Neuro) Pathology, Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The NetherlandsView further author information
,
Isidre Ferreri Neuropathology, Service of Pathology, Bellvitge University Hospital, Barcelona, Spain;j CIBERNED, Hospitalet De Llobregat, University of Barcelona, Barcelona, SpainORCID Iconhttps://orcid.org/0000-0001-9888-8754View further author information
ORCID Icon,
Fabio Coppedèc Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, ItalyView further author information
,
Aron M. Troenk Nutrition and Brain Health Laboratory, the Institute of Biochemistry Food and Nutrition Science, the Robert H. Smith Faculty of Agriculture Food and the Environment, The Hebrew University of Jerusalem, Jerusalem, IsraelORCID Iconhttps://orcid.org/0000-0001-9738-2524View further author information
ORCID Icon &
Andrea Fusoa Department of Experimental Medicine, Sapienza University of Rome, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9467-5671View further author information
ORCID Icon show all
Pages 781-799 | Received 02 Sep 2019, Accepted 20 Jan 2020, Published online: 05 Feb 2020

Citations (31)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Philip Titcombe, Robert Murray, Matthew Hewitt, Elie Antoun, Cyrus Cooper, Hazel M Inskip, Joanna D Holbrook, Keith M Godfrey, Karen Lillycrop, Mark Hanson & Sheila J Barton. (2022) Human non-CpG methylation patterns display both tissue-specific and inter-individual differences suggestive of underlying function. Epigenetics 17:6, pages 653-664.
Read now
Fabio Coppedè. (2021) Epigenetic regulation in Alzheimer’s disease: is it a potential therapeutic target?. Expert Opinion on Therapeutic Targets 25:4, pages 283-298.
Read now

Articles from other publishers (29)

Andrea Fuso. 2024. Epigenetics in Human Disease. Epigenetics in Human Disease 1177 1218 .
Mónica Macías, Blanca Acha, Jon Corroza, Amaya Urdánoz-Casado, Miren Roldan, Maitane Robles, Javier Sánchez-Ruiz de Gordoa, María Elena Erro, Ivonne Jericó, Idoia Blanco-Luquin & Maite Mendioroz. (2023) Liquid Biopsy in Alzheimer’s Disease Patients Reveals Epigenetic Changes in the PRLHR Gene. Cells 12:23, pages 2679.
Crossref
Fayaz Ahmad Mir, Ayeman Amanullah, Buddhi Prakash Jain, Zeeshan Hyderi & Akash Gautam. (2023) Neuroepigenetics of ageing and neurodegeneration-associated dementia: An updated review. Ageing Research Reviews 91, pages 102067.
Crossref
Danko Jeremic, Lydia Jiménez-Díaz & Juan D. Navarro-López. (2023) Targeting epigenetics: A novel promise for Alzheimer’s disease treatment. Ageing Research Reviews 90, pages 102003.
Crossref
Hao‐Yue Qin, Jiao‐Yan Liu, Chang‐Le Fang, Yan‐Ping Deng & Ying Zhang. (2023) DNA methylation: The epigenetic mechanism of Alzheimer's disease. Ibrain.
Crossref
Tiziana Raia, Federica Armeli, Rosaria A. Cavallaro, Giampiero Ferraguti, Rita Businaro, Marco Lucarelli & Andrea Fuso. (2023) Perinatal S-Adenosylmethionine Supplementation Represses PSEN1 Expression by the Cellular Epigenetic Memory of CpG and Non-CpG Methylation in Adult TgCRD8 Mice. International Journal of Molecular Sciences 24:14, pages 11675.
Crossref
Anqi Yang, Saina Yan, Yanfei Yin, Chujie Chen, Xiangwei Tang, Maoliang Ran & Bin Chen. (2023) FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation. International Journal of Molecular Sciences 24:7, pages 6179.
Crossref
Olaia Martínez-Iglesias, Vinogran Naidoo, Iván Carrera, Lola Corzo & Ramón Cacabelos. (2023) Natural Bioactive Products as Epigenetic Modulators for Treating Neurodegenerative Disorders. Pharmaceuticals 16:2, pages 216.
Crossref
Lucia Migliore & Fabio Coppedè. (2022) Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics. Nature Reviews Neurology 18:11, pages 643-660.
Crossref
Brigitte van Zundert & Martin Montecino. (2022) Epigenetic Changes and Chromatin Reorganization in Brain Function: Lessons from Fear Memory Ensemble and Alzheimer’s Disease. International Journal of Molecular Sciences 23:20, pages 12081.
Crossref
Fabio Coppedè, Marica Franzago, Emiliano Giardina, Cristiana Lo Nigro, Giuseppe Matullo, Chiara Moltrasio, Benedetta Nacmias, Silvana Pileggi, Silvia Maria Sirchia, Andrea Stoccoro, Clelia Tiziana Storlazzi, Liborio Stuppia, Rossella Tricarico & Giuseppe Merla. (2022) A perspective on diet, epigenetics and complex diseases: where is the field headed next?. Epigenomics 14:20, pages 1281-1304.
Crossref
He Li, Meiqi Wei, Tianyuan Ye, Yiduan Liu, Dongmei Qi & Xiaorui Cheng. (2022) Identification of the molecular subgroups in Alzheimer's disease by transcriptomic data. Frontiers in Neurology 13.
Crossref
Xiaodie Gao, Qiang Chen, Hua Yao, Jie Tan, Zheng Liu, Yan Zhou & Zhenyou Zou. (2022) Epigenetics in Alzheimer’s Disease. Frontiers in Aging Neuroscience 14.
Crossref
Seth Mikaye Monayo & Xin Liu. (2022) The Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases. Frontiers in Pharmacology 13.
Crossref
Giovanna Blaconà, Roberto Raso, Stefano Castellani, Silvia Pierandrei, Paola Del Porto, Giampiero Ferraguti, Fiorentina Ascenzioni, Massimo Conese & Marco Lucarelli. (2022) Downregulation of epithelial sodium channel (ENaC) activity in cystic fibrosis cells by epigenetic targeting. Cellular and Molecular Life Sciences 79:5.
Crossref
Nuraqila Mohd Murshid, Faridah Aminullah Lubis & Suzana Makpol. (2020) Epigenetic Changes and Its Intervention in Age-Related Neurodegenerative Diseases. Cellular and Molecular Neurobiology 42:3, pages 577-595.
Crossref
Thibaut Gauvrit, Hamza Benderradji, Luc Buée, David Blum & Didier Vieau. (2022) Early-Life Environment Influence on Late-Onset Alzheimer’s Disease. Frontiers in Cell and Developmental Biology 10.
Crossref
Gagandeep Kaur, Suraj Singh S. Rathod, Mohammed M. Ghoneim, Sultan Alshehri, Javed Ahmad, Awanish Mishra & Nabil A. Alhakamy. (2022) DNA Methylation: A Promising Approach in Management of Alzheimer’s Disease and Other Neurodegenerative Disorders. Biology 11:1, pages 90.
Crossref
Fabio Coppede. (2022) Targeting the epigenome to treat neurodegenerative diseases or delay their onset: a perspective. Neural Regeneration Research 17:8, pages 1745.
Crossref
Sabyasachi Maity, Kayla Farrell, Shaghayegh Navabpour, Sareesh Naduvil Narayanan & Timothy J. Jarome. (2021) Epigenetic Mechanisms in Memory and Cognitive Decline Associated with Aging and Alzheimer’s Disease. International Journal of Molecular Sciences 22:22, pages 12280.
Crossref
Miao Xu, JiaYi Zhu, Xian-Dong Liu, Ming-Ying Luo & Nan-Jie Xu. (2021) Roles of physical exercise in neurodegeneration: reversal of epigenetic clock. Translational Neurodegeneration 10:1.
Crossref
Fabio Coppedè. (2021) One-carbon epigenetics and redox biology of neurodegeneration. Free Radical Biology and Medicine 170, pages 19-33.
Crossref
Aina Bellver-Sanchis, Mercè Pallàs & Christian Griñán-Ferré. (2021) The Contribution of Epigenetic Inheritance Processes on Age-Related Cognitive Decline and Alzheimer’s Disease. Epigenomes 5:2, pages 15.
Crossref
Li Wang, Chao-Chao Yu, Xin-Yuan Liu, Xiao-Ni Deng, Qing Tian & Yan-Jun Du. (2021) Epigenetic Modulation of Microglia Function and Phenotypes in Neurodegenerative Diseases. Neural Plasticity 2021, pages 1-13.
Crossref
Silvia Pierandrei, Gessica Truglio, Fabrizio Ceci, Paola Del Porto, Sabina Maria Bruno, Stefano Castellani, Massimo Conese, Fiorentina Ascenzioni & Marco Lucarelli. (2021) DNA Methylation Patterns Correlate with the Expression of SCNN1A, SCNN1B, and SCNN1G (Epithelial Sodium Channel, ENaC) Genes. International Journal of Molecular Sciences 22:7, pages 3754.
Crossref
Andrea Stoccoro & Fabio Coppedè. 2021. Epigenetics in Psychiatry. Epigenetics in Psychiatry 451 488 .
Anna Atlante, Giuseppina Amadoro, Antonella Bobba & Valentina Latina. (2020) Functional Foods: An Approach to Modulate Molecular Mechanisms of Alzheimer’s Disease. Cells 9:11, pages 2347.
Crossref
Xuewen Xiao, Xixi Liu & Bin Jiao. (2020) Epigenetics: Recent Advances and Its Role in the Treatment of Alzheimer's Disease. Frontiers in Neurology 11.
Crossref
Ryan Hogan, Anthony Flamier, Eleonora Nardini & Gilbert Bernier. (2020) The Role of BMI1 in Late-Onset Sporadic Alzheimer’s Disease. Genes 11:7, pages 825.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.