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Epigenetics Volume 15, 2020 - Issue 8
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Research Paper

Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers

Andrew W. CaliriDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USAView further author information
,
Amanda CaceresDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USAView further author information
,
Stella TommasiDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USAView further author information
&
Ahmad BesaratiniaDepartment of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7231-228XView further author information
ORCID Icon
Pages 816-829 | Received 26 Nov 2019, Accepted 27 Jan 2020, Published online: 05 Feb 2020

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Allan Andersen, Rachel Reimer, Kelsey Dawes, Ashley Becker, Natasha Hutchens, Shelly Miller, Meesha Dogan, Brandon Hundley, James A Mills, Jeffrey D Long & Robert Philibert. (2022) DNA methylation differentiates smoking from vaping and non-combustible tobacco use. Epigenetics 17:2, pages 178-190.
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Articles from other publishers (32)

Min-Ae Song, Kellie M. Mori, Joseph P. McElroy, Jo L. Freudenheim, Daniel Y. Weng, Sarah A. Reisinger, Theodore M. Brasky, Mark D. Wewers & Peter G. Shields. (2023) Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers. Clinical Epigenetics 15:1.
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Ayami Sato & Akihito Ishigami. (2023) Effects of heated tobacco product aerosol extracts on DNA methylation and gene transcription in lung epithelial cells. Toxicology and Applied Pharmacology 475, pages 116637.
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Thomas J. Gould. (2023) Epigenetic and long-term effects of nicotine on biology, behavior, and health. Pharmacological Research 192, pages 106741.
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María Paulina Reyes-Mata, Mario Alberto Mireles-Ramírez, Christian Griñán-Ferré, Mercè Pallàs, Lenin Pavón, José de Jesús Guerrero-García & Daniel Ortuño-Sahagún. (2023) Global DNA Methylation and Hydroxymethylation Levels in PBMCs Are Altered in RRMS Patients Treated with IFN-β and GA—A Preliminary Study. International Journal of Molecular Sciences 24:10, pages 9074.
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Stella Tommasi, Hannah Blumenfeld & Ahmad Besaratinia. (2023) Vaping Dose, Device Type, and E-Liquid Flavor are Determinants of DNA Damage in Electronic Cigarette Users. Nicotine and Tobacco Research 25:6, pages 1145-1154.
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Bernal Camila, Camero Carlos, Pinzón Maria-Jose, Rodríguez Sergio, Cañas Alejandra & Rojas Adriana. (2023) Genotoxicity and hypomethylation of LINE-1 induced by electronic cigarettes. Ecotoxicology and Environmental Safety 256, pages 114900.
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Ahmad Besaratinia. (2023) The State of Research and Weight of Evidence on the Epigenetic Effects of Bisphenol A. International Journal of Molecular Sciences 24:9, pages 7951.
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Sara Trifunovic, Katarina Smiljanić, Albert Sickmann, Fiorella A. Solari, Stoimir Kolarevic, Aleksandra Divac Rankov & Mila Ljujic. (2022) Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells. Respiratory Research 23:1.
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Lu Wu, Han Li, Fuping Ye, Yongyue Wei, Wenqi Li, Yuan Xu, Haibo Xia, Jingshu Zhang, Lianxian Guo, Guiwei Zhang, Feng Chen & Qizhan Liu. (2022) As3MT-mediated SAM consumption, which inhibits the methylation of histones and LINE1, is involved in arsenic-induced male reproductive damage. Environmental Pollution 313, pages 120090.
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Doris Loh & Russel J. Reiter. (2022) Melatonin: Regulation of Viral Phase Separation and Epitranscriptomics in Post-Acute Sequelae of COVID-19. International Journal of Molecular Sciences 23:15, pages 8122.
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Loren E. Wold, Robert Tarran, Laura E. Crotty Alexander, Naomi M. Hamburg, Farrah Kheradmand, Gideon St. Helen & Joseph C. Wu. (2022) Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association. Circulation Research 131:3.
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Reiner Hanewinkel, Kathrin Niederberger, Anya Pedersen, Jennifer B. Unger & Artur Galimov. (2022) E-cigarettes and nicotine abstinence: a meta-analysis of randomised controlled trials. European Respiratory Review 31:163, pages 210215.
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Ahmad Besaratinia, Amanda Caceres & Stella Tommasi. (2022) DNA Hydroxymethylation in Smoking-Associated Cancers. International Journal of Molecular Sciences 23:5, pages 2657.
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Zhongxiao Lin, Qian Ding, Xinzhi Li, Yuliang Feng, Hao He, Chuoji Huang & YiZhun Zhu. (2022) Targeting Epigenetic Mechanisms in Vascular Aging. Frontiers in Cardiovascular Medicine 8.
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Rebecca C. Richmond, Carlos Sillero-Rejon, Jasmine N. Khouja, Claire Prince, Alexander Board, Gemma Sharp, Matthew Suderman, Caroline L. Relton, Marcus Munafò & Suzanne H. Gage. (2021) Investigating the DNA methylation profile of e-cigarette use. Clinical Epigenetics 13:1.
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Ahmad Besaratinia. (2021) From Tobacco Cigarettes to Electronic Cigarettes: The Two Sides of a Nicotine Coin. Frontiers in Oral Health 2.
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Stella Tommasi, Niccolo Pabustan, Meng Li, Yibu Chen, Kimberly D. Siegmund & Ahmad Besaratinia. (2021) A novel role for vaping in mitochondrial gene dysregulation and inflammation fundamental to disease development. Scientific Reports 11:1.
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Laura Libera, Giorgia Ottini, Nora Sahnane, Fabiana Pettenon, Mario Turri-Zanoni, Alessia Lambertoni, Anna Maria Chiaravalli, Federico Leone, Paolo Battaglia, Paolo Castelnuovo, Silvia Uccella, Daniela Furlan, Carla Facco & Fausto Sessa. (2021) Methylation Drivers and Prognostic Implications in Sinonasal Poorly Differentiated Carcinomas. Cancers 13:19, pages 5030.
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Maria Sergeevna Protasova, Tatiana Vladimirovna Andreeva & Evgeny Ivanovich Rogaev. (2021) Factors Regulating the Activity of LINE1 Retrotransposons. Genes 12:10, pages 1562.
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Ahmad Besaratinia. (2021) COVID-19: a pandemic converged with global tobacco epidemic and widespread vaping—state of the evidence. Carcinogenesis 42:8, pages 1009-1022.
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Ahmad Besaratinia & Stella Tommasi. (2021) The consequential impact of JUUL on youth vaping and the landscape of tobacco products: The state of play in the COVID-19 era. Preventive Medicine Reports 22, pages 101374.
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Samantha R. McDonough, Irfan Rahman & Isaac Kirubakaran Sundar. (2021) Recent updates on biomarkers of exposure and systemic toxicity in e-cigarette users and EVALI. American Journal of Physiology-Lung Cellular and Molecular Physiology 320:5, pages L661-L679.
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Rui Yan, Xu-Li Chen, Yan-Ming Xu & Andy T. Y. Lau. (2021) Epimutational effects of electronic cigarettes. Environmental Science and Pollution Research 28:14, pages 17044-17067.
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Zidian Xie, Irfan Rahman, Maciej L Goniewicz & Dongmei Li. (2021) Perspectives on Epigenetics Alterations Associated with Smoking and Vaping. Function 2:3.
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Ying Yin, Xiao-zhao Liu, Ximiao He & Li-quan Zhou. (2021) Exogenous Coronavirus Interacts With Endogenous Retrotransposon in Human Cells. Frontiers in Cellular and Infection Microbiology 11.
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Richard J. WangSudhamayi BhadrirajuStanton A. Glantz. (2021) E-Cigarette Use and Adult Cigarette Smoking Cessation: A Meta-Analysis. American Journal of Public Health 111:2, pages 230-246.
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Nicolás Niederbacher, Litzy Bermudez, Daniel González, Camila Bernal, Francisco García, Daniel León, Maria Pinzón, Carlos Camero, Ithzayana Madariaga, Paula Sánchez, Andrea Rodríguez, Salime Hurtado, Catherine Tovar, Santiago Rodríguez‑Ariza, Rafael Castro, Mariana Guerra, Alejandra Cañas & Adriana Rojas. (2021) Electronic cigarettes: Genetic and epigenetic impact (Review). International Journal of Epigenetics 1:1.
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Andrew W. Caliri, Stella Tommasi & Ahmad Besaratinia. (2021) Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer. Mutation Research/Reviews in Mutation Research 787, pages 108365.
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Rachel L. Miller & Jessica Oh. 2021. Medical Epigenetics. Medical Epigenetics 51 79 .
Wardah Mahmood, Lars Erichsen, Pauline Ott, Wolfgang A. Schulz, Johannes C. Fischer, Marcos J. Arauzo-Bravo, Marcelo L. Bendhack, Mohamed Hassan & Simeon Santourlidis. (2020) RETRACTED ARTICLE: Aging-associated distinctive DNA methylation changes of LINE-1 retrotransposons in pure cell-free DNA from human blood. Scientific Reports 10:1.
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Abby C. Lee, Jaideep Chakladar, Wei Tse Li, Chengyu Chen, Eric Y. Chang, Jessica Wang-Rodriguez & Weg M. Ongkeko. (2020) Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune Dysregulation. International Journal of Molecular Sciences 21:15, pages 5513.
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Ahmad Besaratinia & Stella Tommasi. (2020) Vaping epidemic: challenges and opportunities. Cancer Causes & Control 31:7, pages 663-667.
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