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Epigenetics Volume 16, 2021 - Issue 1
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Research Paper

Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells

Terisha GhaziDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban, South AfricaView further author information
,
Savania NagiahDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban, South AfricaView further author information
&
Anil A. ChuturgoonDiscipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban, South AfricaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4649-4133View further author information
ORCID Icon
Pages 79-91 | Received 13 Feb 2020, Accepted 02 Jun 2020, Published online: 07 Jul 2020

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Terisha Ghazi, Savania Nagiah & Anil A. Chuturgoon. (2022) Fusaric acid induces hepatic global m6A RNA methylation and differential expression of m6A regulatory genes in vivo - a pilot study. Epigenetics 17:6, pages 695-703.
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Haifeng Jin, Zheng Wu, Bibo Tan, Zhen Liu, Zhanfei Zu, Xiaoyun Wu, Yuwang Bi & Xingmao Hu. (2022) Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells. Bioengineered 13:6, pages 14595-14604.
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Chenchen Ma, Kaining Chen, Yuanyuan Wang, Chaoping Cen, Qixiao Zhai & Jiachao Zhang. (2021) Establishing a novel colorectal cancer predictive model based on unique gut microbial single nucleotide variant markers. Gut Microbes 13:1.
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Articles from other publishers (21)

Xin Zhen, Yuxiang Sun, Hongchun Lin, Yuebo Huang, Tianwei Liu, Yuanqing Li & Hui Peng. (2023) Elucidating the role of nicotinamide N-methyltransferase-p53 axis in the progression of chronic kidney disease. PeerJ 11, pages e16301.
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Liping Wu & Hongliang Tang. (2023) The role of N6-methyladenosine modification in rodent models of neuropathic pain: from the mechanism to therapeutic potential. Biomedicine & Pharmacotherapy 166, pages 115398.
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Lili Feng, Rongrong Du, Baitong Chang, Min Li, Jie Tian & Shengjun Wang. (2023) Multilevel regulation of N6-methyladenosine RNA modifications: Implications in tumorigenesis and therapeutic opportunities. Genes & Diseases 10:5, pages 1969-1981.
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Jiexuan Hu, Haishan Lin, Cong Wang, Qiang Su & Bangwei Cao. (2023) METTL14‑mediated RNA methylation in digestive system tumors. International Journal of Molecular Medicine 52:3.
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Mücahit Seçme, Ayşen Buket Er Urgancı, Ramazan Üzen, Ali Aslan & Fatih Tıraş. (2023) Determination of the effects of fusaric acid, a mycotoxin, on cytotoxicity, gamma-H2AX, 8-hydroxy-2 deoxyguanosine and DNA repair gene expressions in pancreatic cancer cells. Toxicon 231, pages 107179.
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Cui Yang, Jing Sun, Zhaoqun Wu, Maozhu Jiang, Dayong Li, Xinjie Wang, Chunxiang Zhou, Xuecheng Liu, Zhiguo Ren, Jun Wang, Manli Sun, Wenxian Sun & Jie Gao. (2023) FoRSR1 Is Important for Conidiation, Fusaric Acid Production, and Pathogenicity in Fusarium oxysporum f. sp. ginseng . Phytopathology® 113:7, pages 1244-1253.
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Lulu Li, Ziqi He, Yang Shi, Huiying Sun, Bowei Yuan, Jing Cai, Jia Chen & Miao Long. (2023) Role of epigenetics in mycotoxin toxicity: A review. Environmental Toxicology and Pharmacology 100, pages 104154.
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Xiaofang Zhu, Haowei Fu, Jiahui Sun & Qian Xu. (2023) Interaction between N6-methyladenosine (m6A) modification and environmental chemical-induced diseases in various organ systems. Chemico-Biological Interactions 373, pages 110376.
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Gargi Sarraf & Ravindresh Chhabra. (2023) Emerging role of mRNA methylation in regulating the hallmarks of cancer. Biochimie 206, pages 61-72.
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Zhaotong Wang, Jiawang Zhou, Haisheng Zhang, Lichen Ge, Jiexin Li & Hongsheng Wang. (2022) RNA m 6 A methylation in cancer . Molecular Oncology 17:2, pages 195-229.
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Aju Kisan & Ravindresh Chhabra. (2022) Modulation of gene expression by YTH domain family (YTHDF) proteins in human physiology and pathology. Journal of Cellular Physiology 238:1, pages 5-31.
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Jun Wu, Xiaoqin Wang & Xin Li. (2022) N6-methyladenosine methylation regulator FTO promotes oxidative stress and induces cell apoptosis in ovarian cancer. Epigenomics 14:23, pages 1509-1522.
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Yanlu Feng, Tong Liu, Siyi Xu, Yiyi Ren, Yiling Ge, Lihong Yin, Yuepu Pu & Geyu Liang. (2022) The role of N6-methyladenosine methylation in environmental exposure-induced health damage. Environmental Science and Pollution Research 29:46, pages 69153-69175.
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Zhelin Xia, Fanhua Kong, Kunpeng Wang & Xin Zhang. (2022) Role of N6-Methyladenosine Methylation Regulators in the Drug Therapy of Digestive System Tumours. Frontiers in Pharmacology 13.
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Xiangli Liu, Ziyi Wang, Qiwei Yang, Xiaohai Hu, Qiang Fu, Xinyu Zhang & Wenya Li. (2022) RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53. Frontiers in Oncology 12.
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Li-Juan Deng, Wei-Qing Deng, Shu-Ran Fan, Min-Feng Chen, Ming Qi, Wen-Yu Lyu, Qi Qi, Amit K. Tiwari, Jia-Xu Chen, Dong-Mei Zhang & Zhe-Sheng Chen. (2022) m6A modification: recent advances, anticancer targeted drug discovery and beyond. Molecular Cancer 21:1.
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Zhenwei Li, Qingqing Xu, Ning Huangfu, Xiaomin Chen & Jianhua Zhu. (2021) Mettl3 promotes oxLDL‐mediated inflammation through activating STAT1 signaling. Journal of Clinical Laboratory Analysis 36:1.
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Terisha Ghazi & Anil A Chuturgoon. (2021) Mycotoxins exacerbate HIV infection: the potential of N 6 -methyladenosine RNA methylation . Epigenomics 13:24, pages 1905-1908.
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Junchao Huang, Yingjie Shao & Wendong Gu. (2021) Function and clinical significance of N6-methyladenosine in digestive system tumours. Experimental Hematology & Oncology 10:1.
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Jing-Jing Jing, Xu Zhao, Hao Li, Li-ping Sun & Yuan Yuan. (2021) Expression profiles and prognostic roles of m6A writers, erasers and readers in gastric cancer. Future Oncology 17:20, pages 2605-2620.
Crossref
Thilona Arumugam, Terisha Ghazi & Anil A. Chuturgoon. (2021) Fumonisin B1 alters global m6A RNA methylation and epigenetically regulates Keap1-Nrf2 signaling in human hepatoma (HepG2) cells. Archives of Toxicology 95:4, pages 1367-1378.
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