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Original Research

Lactoferrin-decorated vs PEGylated zein nanospheres for combined aromatase inhibitor and herbal therapy of breast cancer

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Pages 835-850 | Received 16 Mar 2018, Accepted 24 Jul 2018, Published online: 10 Aug 2018

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Read on this site (6)

Xi Luo, Sudan Wu, Meng Xiao, Huan Gu, Huan Zhang, Jianping Chen, Yang Liu, Chen Zhang & Jinming Zhang. (2023) Advances and Prospects of Prolamine Corn Protein Zein as Promising Multifunctional Drug Delivery System for Cancer Treatment. International Journal of Nanomedicine 18, pages 2589-2621.
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Hussam I Kutbi, Ahmed K Kammoun & Dalia Farag El-Telbany. (2021) Amelioration of Pterostilbene Antiproliferative, Proapoptotic, and Oxidant Potentials in Human Breast Cancer MCF7 Cells Using Zein Nanocomposites. International Journal of Nanomedicine 16, pages 3059-3071.
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Salma M Mohyeldin, Wael M Samy, Doaa Ragab, Doaa A Abdelmonsif, Rania G Aly & Nazik A Elgindy. (2021) Precisely Fabricated Sulpiride-Loaded Nanolipospheres with Ameliorated Oral Bioavailability and Antidepressant Activity. International Journal of Nanomedicine 16, pages 2013-2044.
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Doaa M. Anwar, Mousa El-Sayed, Asmaa Reda, Jia-You Fang, Sherine N. Khattab & Ahmed O. Elzoghby. (2021) Recent advances in herbal combination nanomedicine for cancer: delivery technology and therapeutic outcomes. Expert Opinion on Drug Delivery 18:11, pages 1609-1625.
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Nabila A. El-Sheridy, Riham M. El-Moslemany, Alyaa A. Ramadan, Maged W. Helmy & Labiba K. El-Khordagui. (2021) Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules. Drug Delivery 28:1, pages 906-919.
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Sarah A El-Lakany, Ahmed I Abd-Elhamid, Elbadawy A Kamoun, Esmail M El-Fakharany, Wael M Samy & Nazik A Elgindy. (2019) α-Bisabolol-Loaded Cross-Linked Zein Nanofibrous 3D-Scaffolds For Accelerating Wound Healing And Tissue Regeneration In Rats. International Journal of Nanomedicine 14, pages 8251-8270.
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Articles from other publishers (26)

Jinlu Shang, Jing Yang, Qinmin Deng & Meiling Zhou. (2023) Nano-scale drug delivery systems for luteolin: advancements and applications. Journal of Materials Chemistry B 11:47, pages 11198-11216.
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Sajad Fakhri, Seyed Zachariah Moradi, Farahnaz Faraji, Tara Farhadi, Osman Hesami, Amin Iranpanah, Kassidy Webber & Anupam Bishayee. (2023) Current advances in nanoformulations of therapeutic agents targeting tumor microenvironment to overcome drug resistance. Cancer and Metastasis Reviews 42:3, pages 959-1020.
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Reihaneh Ramezani, Mozhdeh Mohammadian, Elaheh Sadat Hosseini & Mehrak Zare. (2023) The effect of bovine milk lactoferrin-loaded exosomes (exoLF) on human MDA-MB-231 breast cancer cell line. BMC Complementary Medicine and Therapies 23:1.
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Amira E. El-Nahas, Heba M. Elbedaiwy, Inas M. Masoud, Rania G. Aly, Maged W. Helmy & Amal H. El-Kamel. (2023) Berberine-loaded zein/hyaluronic acid composite nanoparticles for efficient brain uptake to alleviate neuro-degeneration in the pilocarpine model of epilepsy. European Journal of Pharmaceutics and Biopharmaceutics 188, pages 182-200.
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Alaa R. Aboushanab, Riham M. El-Moslemany, Amal H. El-Kamel, Radwa A. Mehanna, Basant A. Bakr & Asmaa A. Ashour. (2023) Targeted Fisetin-Encapsulated β-Cyclodextrin Nanosponges for Breast Cancer. Pharmaceutics 15:5, pages 1480.
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Francesca Tivano & Valeria Chiono. (2023) Zein as a renewable material for the preparation of green nanoparticles for drug delivery. Frontiers in Biomaterials Science 2.
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Wenquan Huang, Zhiqiang Li, Weiqi Liu, Shiyuan Liu, Rujin Zhou & Yanbin Jiang. (2023) Preparation of B16 cancer cell membrane coated α-zein biomimetic drug delivery system for the enhancement of homotypic target ability. Industrial Crops and Products 194, pages 116301.
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Ana Caroline Jaski, Francielle Schmitz, Rayta Paim Horta, Larissa Cadorin, Bruno José Gonçalves da Silva, Jürgen Andreaus, Maria Cristina Dias Paes, Izabel C. Riegel-Vidotti & Lizandra Maria Zimmermann. (2022) Zein - a plant-based material of growing importance: New perspectives for innovative uses. Industrial Crops and Products 186, pages 115250.
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Shashank Chaturvedi & Anuj Garg. (2022) A comprehensive review on novel delivery approaches for exemestane. Journal of Drug Delivery Science and Technology 75, pages 103655.
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Mai A. Atallah, Marwa A. Sallam, Mona A. Abdelmoneem, Mohamed Teleb, Kadria A. Elkhodairy, Adnan A. Bekhit, Asmaa F. Khafaga, Ahmed E. Noreldin, Ahmed O. Elzoghby & Sherine N. Khattab. (2022) Green self-assembled lactoferrin carboxymethyl cellulose nanogels for synergistic chemo/herbal breast cancer therapy. Colloids and Surfaces B: Biointerfaces 217, pages 112657.
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Marta S. Laranjeira, Tiago P. Ribeiro, Ana I. Magalhães, Pedro C. Silva, João A.M. Santos & Fernando J. Monteiro. (2022) Magnetic mesoporous silica nanoparticles as a theranostic approach for breast cancer: Loading and release of the poorly soluble drug exemestane. International Journal of Pharmaceutics 619, pages 121711.
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Zhenyao Wu, Jie Li, Xin Zhang, Yangjia Li, Dongwei Wei, Lichang Tang, Shiming Deng & Guijin Liu. (2022) Rational Fabrication of Folate-Conjugated Zein/Soy Lecithin/Carboxymethyl Chitosan Core–Shell Nanoparticles for Delivery of Docetaxel. ACS Omega 7:15, pages 13371-13381.
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Sarah Mokhtar, Sherine N. Khattab, Kadria A. Elkhodairy, Mohamed Teleb, Adnan A. Bekhit, Ahmed O. Elzoghby & Marwa A. Sallam. (2022) Methotrexate-Lactoferrin Targeted Exemestane Cubosomes for Synergistic Breast Cancer Therapy. Frontiers in Chemistry 10.
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Tasneem A. Nasser, Ahmed S. AbdElhamid, Mohamed Teleb, Sherine N. Khattab, Adnan A. Bekhit, Kadria A. Elkhodairy & Ahmed O. Elzoghby. 2022. Combination Drug Delivery Approach as an Effective Therapy for Various Diseases. Combination Drug Delivery Approach as an Effective Therapy for Various Diseases 353 396 .
Ramez M. Rashad ElSayed, Dalia E. Hussein, Ahmed S. AbdElhamid, Adnan A. Bekhit, Mohamed Teleb, Kadria A. Elkhodairy, Sherine N. Khattab & Ahmed O. Elzoghby. 2022. Hybrid Nanomaterials for Drug Delivery. Hybrid Nanomaterials for Drug Delivery 187 225 .
Sara I. Aboras, Mohamed A. Korany, Heba H. Abdine, Marwa A.A. Ragab, Ahmed El Diwany & Mona M. Agwa. (2021) HPLC with fluorescence detection for the bioanalysis and pharmacokinetic study of Doxorubicin and Prodigiosin loaded on eco-friendly casein nanomicelles in rat plasma. Journal of Chromatography B 1187, pages 123043.
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Inés Abad, Celia Conesa & Lourdes Sánchez. (2021) Development of Encapsulation Strategies and Composite Edible Films to Maintain Lactoferrin Bioactivity: A Review. Materials 14:23, pages 7358.
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Ahmed M. Abdelsalam, Ahmed Somaida, Abdallah Mohamed Ayoub, Fahd M. Alsharif, Eduard Preis, Matthias Wojcik & Udo Bakowsky. (2021) Surface-Tailored Zein Nanoparticles: Strategies and Applications. Pharmaceutics 13:9, pages 1354.
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Osama R.M. Metawea, Mona A. Abdelmoneem, Nesreen Saied Haiba, Hosam H. Khalil, Mohamed Teleb, Ahmed O. Elzoghby, Asmaa F. Khafaga, Ahmed E. Noreldin, Fernando Albericio & Sherine N. Khattab. (2021) A novel ‘smart’ PNIPAM-based copolymer for breast cancer targeted therapy: Synthesis, and characterization of dual pH/temperature-responsive lactoferrin-targeted PNIPAM-co-AA. Colloids and Surfaces B: Biointerfaces 202, pages 111694.
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Mardi M. Algandaby & Majid M. Al-Sawahli. (2021) Augmentation of anti-proliferative, pro-apoptotic and oxidant profiles induced by piceatannol in human breast carcinoma MCF-7 cells using zein nanostructures. Biomedicine & Pharmacotherapy 138, pages 111409.
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Mona M. Agwa & Sally Sabra. (2021) Lactoferrin coated or conjugated nanomaterials as an active targeting approach in nanomedicine. International Journal of Biological Macromolecules 167, pages 1527-1543.
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Ahmed O. Elzoghby, Mona A. Abdelmoneem, Islam A. Hassanin, Mahmoud M. Abd Elwakil, Manar A. Elnaggar, Sarah Mokhtar, Jia-You Fang & Kadria A. Elkhodairy. (2020) Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand. Biomaterials 263, pages 120355.
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Sarah A. El-Lakany, Elbadawy A. Kamoun, Ahmed I. Abd-Elhamid, Rania G. Aly, Wael M. Samy & Nazik A. Elgindy. (2020) Graphene oxide crosslinked-zein nanofibrous scaffolds for prominent Cu-adsorption as tissue regeneration promoters in diabetic rats: Nanofibers optimization and in vivo assessment. International Journal of Pharmaceutics 590, pages 119919.
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Anand K Kondapi. (2020) Targeting cancer with lactoferrin nanoparticles: recent advances. Nanomedicine 15:21, pages 2071-2083.
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Phuong H.L. Tran, Wei Duan, Beom-Jin Lee & Thao T.D. Tran. (2019) The use of zein in the controlled release of poorly water-soluble drugs. International Journal of Pharmaceutics 566, pages 557-564.
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Marta Laranjeira, Tiago P. Ribeiro, Ana Isabel Magalhães, Pedro C. Silva, João A. M. Santos & Fernando Monteiro. (2021) Magnetic Mesoporous Silica Nanoparticles as a Theranostic Approach for Breast Cancer: Loading and Release of the Poorly Soluble Drug Exemestane. SSRN Electronic Journal.
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