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Expert Opinion on Drug Delivery Volume 16, 2019 - Issue 6
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Review

Peptide-mediated drug delivery across the blood-brain barrier for targeting brain tumors

Behzad JafariResearch Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran;Department of Medicinal Chemistry, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, IranView further author information
,
Mohammad M. PourseifResearch Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, IranORCID Iconhttps://orcid.org/0000-0001-8314-2853View further author information
ORCID Icon,
Jaleh BararResearch Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran;Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranView further author information
,
Mohammad A. RafiDepartment of Neurology, College of Medicine, Thomas Jefferson University, Philadelphia, PA, USAView further author information
&
Yadollah OmidiResearch Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran;Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, IranCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0067-2475View further author information
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Pages 583-605 | Received 27 Jan 2019, Accepted 01 May 2019, Published online: 20 May 2019

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Karolina Pierzynowska, Joanna Morcinek-Orłowska, Lidia Gaffke, Weronika Jaroszewicz, Piotr M. Skowron & Grzegorz Węgrzyn. (2023) Applications of the phage display technology in molecular biology, biotechnology and medicine. Critical Reviews in Microbiology 0:0, pages 1-41.
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Yanning Bao & Weiyue Lu. (2023) Targeting cerebral diseases with enhanced delivery of therapeutic proteins across the blood-brain barrier. Expert Opinion on Drug Delivery 0:0, pages 1-18.
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Hai Song, Zhongyun Ding, Jilin Chen, Tingbao Chen, Tinghua Wang & Jin Huang. (2022) The AMPK-SIRT1-FoxO1-NF-κB signaling pathway participates in hesperetin-mediated neuroprotective effects against traumatic brain injury via the NLRP3 inflammasome. Immunopharmacology and Immunotoxicology 44:6, pages 970-983.
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Azam Safary, Hakimeh Moghaddas-Sani, Mostafa Akbarzadeh-Khiavi, Alireza Khabbazzi, Mohammad A. Rafi & Yadollah Omidi. (2021) Enzyme replacement combinational therapy: effective treatments for mucopolysaccharidoses. Expert Opinion on Biological Therapy 21:9, pages 1181-1197.
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Yadollah Omidi, Nazanin Kianinejad, Young Kwon & Hossein Omidian. (2021) Drug delivery and targeting to brain tumors: considerations for crossing the blood-brain barrier. Expert Review of Clinical Pharmacology 14:3, pages 357-381.
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Khushwant S. Yadav, Archana Upadhya & Ambikanandan Misra. (2021) Targeted drug therapy in nonsmall cell lung cancer: clinical significance and possible solutions-part II (role of nanocarriers). Expert Opinion on Drug Delivery 18:1, pages 103-118.
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Vala Kafil, Amir Ata Saei, Mohammad Reza Tohidkia, Jaleh Barar & Yadollah Omidi. (2020) Immunotargeting and therapy of cancer by advanced multivalence antibody scaffolds. Journal of Drug Targeting 28:10, pages 1018-1033.
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Faheem Hyder Pottoo, Shrestha Sharma, Md. Noushad Javed, Md. Abul Barkat, Harshita, Md. Sabir Alam, Mohd. Javed Naim, Ozair Alam, Mohammad Azam Ansari, George E. Barreto & Ghulam Md. Ashraf. (2020) Lipid-based nanoformulations in the treatment of neurological disorders. Drug Metabolism Reviews 52:1, pages 185-204.
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Saikat Ghosh, Rohan Lalani, Vivek Patel, Subhas Bhowmick & Ambikanandan Misra. (2019) Surface engineered liposomal delivery of therapeutics across the blood brain barrier: recent advances, challenges and opportunities. Expert Opinion on Drug Delivery 16:12, pages 1287-1311.
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Nazanin Kianinejad & Young Min Kwon. (2022) Dual-targeting of brain tumors with nanovesicles. BioImpacts 13:1, pages 1-3.
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Shirin Ahmadi, Marziyeh Fathi & Yadollah Omidi. 2023. Polymeric Nanosystems. Polymeric Nanosystems 85 111 .
Angela Chiew Wen Ch’ng, Zoltán Konthur & Theam Soon Lim. 2023. Phage Display. Phage Display 291 313 .
Barindra Sana, Ding Ke, Eunice Hui Yen Li, Timothy Ho, Jayasree Seayad, Hung A. Duong & Farid J. Ghadessy. (2022) Halogenation of Peptides and Proteins Using Engineered Tryptophan Halogenase Enzymes. Biomolecules 12:12, pages 1841.
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Shanshan Zhang, Lin Gan, Fengye Cao, Hao Wang, Peng Gong, Congcong Ma, Li Ren, Yubo Lin & Xianming Lin. (2022) The barrier and interface mechanisms of the brain barrier, and brain drug delivery. Brain Research Bulletin 190, pages 69-83.
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Hira Choudhury, Manisha Pandey, Raxshanaa Mohgan, Jim Sii Jack Jong, Roshini Nicole David, Wan Yi Ngan, Tze Liang Chin, Shereen Ting, Prashant Kesharwani & Bapi Gorain. (2022) Dendrimer-based delivery of macromolecules for the treatment of brain tumor. Biomaterials Advances 141, pages 213118.
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Sarabjit Kaur, Satish K. Pandey, Deepika Sharma, Rohit K. Sharma & Nishima Wangoo. (2022) Enkephalin loaded and RGD decorated PLGA–poloxamer nanoparticles for effective targeting in cancer cells. Journal of Materials Science 57:36, pages 17416-17432.
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Xihui Gao, Jinliang Xu, Tingting Yao, Xiaoxiao Liu, Hanchang Zhang & Changyou Zhan. (2022) Peptide-decorated nanocarriers penetrating the blood-brain barrier for imaging and therapy of brain diseases. Advanced Drug Delivery Reviews 187, pages 114362.
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Meiqi Chang, Caihong Dong, Hui Huang, Li Ding, Wei Feng & Yu Chen. (2022) Nanobiomimetic Medicine. Advanced Functional Materials 32:32.
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Namrata Chakravarty, Anshu Mathur & R. P. Singh. 2022. Engineered Nanomaterials for Innovative Therapies and Biomedicine. Engineered Nanomaterials for Innovative Therapies and Biomedicine 67 98 .
Baichen Xiong, Yuanyuan Wang, Ying Chen, Shuaishuai Xing, Qinghong Liao, Yao Chen, Qi Li, Wei Li & Haopeng Sun. (2021) Strategies for Structural Modification of Small Molecules to Improve Blood–Brain Barrier Penetration: A Recent Perspective. Journal of Medicinal Chemistry 64:18, pages 13152-13173.
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Haiyang Wu, Yan Zhou, Yulin Wang, Linjian Tong, Fanchen Wang, Sirong Song, Lixia Xu, Baolong Liu, Hua Yan & Zhiming Sun. (2021) Current State and Future Directions of Intranasal Delivery Route for Central Nervous System Disorders: A Scientometric and Visualization Analysis. Frontiers in Pharmacology 12.
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Xue Zhou, Quentin R. Smith & Xinli Liu. (2021) Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases . WIREs Nanomedicine and Nanobiotechnology 13:4.
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Sofia Parrasia, Andrea Rossa, Tatiana Varanita, Vanessa Checchetto, Riccardo De Lorenzi, Mario Zoratti, Cristina Paradisi, Paolo Ruzza, Andrea Mattarei, Ildikò Szabò & Lucia Biasutto. (2021) An Angiopep2-PAPTP Construct Overcomes the Blood-Brain Barrier. New Perspectives against Brain Tumors. Pharmaceuticals 14:2, pages 129.
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Rizwana Khatoon, Md Aftab Alam & Pramod Kumar Sharma. (2021) Current approaches and prospective drug targeting to brain. Journal of Drug Delivery Science and Technology 61, pages 102098.
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M. Masmudi-Martín, L. Zhu, M. Sanchez-Navarro, N. Priego, M. Casanova-Acebes, V. Ruiz-Rodado, E. Giralt & M. Valiente. (2021) Brain metastasis models: What should we aim to achieve better treatments?. Advanced Drug Delivery Reviews 169, pages 79-99.
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Pengbo Guo, Mengjie Si, Di Wu, Hui Yi Xue, Wenhui Hu & Ho Lun Wong. (2020) Incorporation of docosahexaenoic acid (DHA) enhances nanodelivery of antiretroviral across the blood-brain barrier for treatment of HIV reservoir in brain. Journal of Controlled Release 328, pages 696-709.
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Kishu Ranjan, Bhargav N Waghela, Foram U Vaidya & Chandramani Pathak. (2020) Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells. International Journal of Molecular Sciences 21:18, pages 6890.
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Mitra Dolatkhah, Nastaran Hashemzadeh, Jaleh Barar, Khosro Adibkia, Ayuob Aghanejad, Mohammad Barzegar-Jalali & Yadollah Omidi. (2020) Graphene-based multifunctional nanosystems for simultaneous detection and treatment of breast cancer. Colloids and Surfaces B: Biointerfaces 193, pages 111104.
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Azita Moradi, Mohammad M. Pourseif, Behzad Jafari, Sepideh Parvizpour & Yadollah Omidi. (2020) Nanobody-based therapeutics against colorectal cancer: Precision therapies based on the personal mutanome profile and tumor neoantigens. Pharmacological Research 156, pages 104790.
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Amy J. Tibbo & George S. Baillie. (2020) Phosphodiesterase 4B: Master Regulator of Brain Signaling. Cells 9:5, pages 1254.
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Sunil Kumar Dubey, K.K. Lakshmi, Kowthavarapu Venkata Krishna, Mukta Agrawal, Gautam Singhvi, Ranendra Narayana Saha, Swarnlata Saraf, Shailendra Saraf, Rahul Shukla & Amit Alexander. (2020) Insulin mediated novel therapies for the treatment of Alzheimer's disease. Life Sciences 249, pages 117540.
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Somayeh Vandghanooni, Jaleh Barar, Morteza Eskandani & Yadollah Omidi. (2020) Aptamer-conjugated mesoporous silica nanoparticles for simultaneous imaging and therapy of cancer. TrAC Trends in Analytical Chemistry 123, pages 115759.
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Luiza Steffens, Ana Moira Morás, Pablo Ricardo Arantes, Kevin Masterson, Zhi Cao, Michael Nugent & Dinara Jaqueline Moura. (2020) Electrospun PVA-Dacarbazine nanofibers as a novel nano brain-implant for treatment of glioblastoma: in silico and in vitro characterization. European Journal of Pharmaceutical Sciences 143, pages 105183.
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John JE Mulvihill, Eoghan M Cunnane, Aisling M Ross, Jason T Duskey, Giovanni Tosi & Andreas M Grabrucker. (2020) Drug delivery across the blood–brain barrier: recent advances in the use of nanocarriers. Nanomedicine 15:2, pages 205-214.
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Marziyeh Fathi, Azam Safary & Jaleh Barar. (2019) Therapeutic impacts of enzyme-responsive smart nanobiosystems. BioImpacts 10:1, pages 1-4.
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