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Expert Opinion on Drug Delivery Volume 16, 2019 - Issue 6
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Original Research

Population pharmacokinetics of oxycodone in plasma and cerebrospinal fluid after epidural and intravenous administration

M. LamminsaloSchool of Pharmacy, University of Eastern Finland, Kuopio, FinlandView further author information
,
P. PiirainenSchool of Medicine, University of Eastern Finland, Kuopio, FinlandView further author information
,
H. KokkiSchool of Medicine, University of Eastern Finland, Kuopio, FinlandView further author information
,
C. A. J. KnibbeDivision of Pharmacology, Leiden University, Leiden, The NetherlandsView further author information
,
V.-P. RantaSchool of Pharmacy, University of Eastern Finland, Kuopio, FinlandView further author information
,
P. VälitaloSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland;Finnish Medicines Agency, Assessment of Medicinal Products Department, Pharmacobiological Unit, Kuopio, FinlandView further author information
&
Merja KokkiSchool of Medicine, University of Eastern Finland, Kuopio, Finland;Department of Anesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, FinlandCorrespondence[email protected]
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Pages 649-656 | Received 20 Feb 2019, Accepted 09 May 2019, Published online: 22 May 2019

Citations (5)

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Antti Valtola, James D. Morse, Pawel Florkiewicz, Heidi Hautajärvi, Pasi Lahtinen, Tadeusz Musialowicz, Brian J. Anderson, Veli-Pekka Ranta & Hannu Kokki. (2020) Bioavailability of oxycodone by mouth in coronary artery bypass surgery patients – a randomized trial. Journal of Drug Assessment 9:1, pages 117-128.
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Articles from other publishers (4)

Panu Piirainen, Hannu Kokki & Merja Kokki. (2022) Epidural Oxycodone for Acute Pain. Pharmaceuticals 15:5, pages 643.
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Bram C. Agema, Astrid W. Oosten, Sebastiaan D.T. Sassen, Wim J.R. Rietdijk, Carin C.D. van der Rijt, Birgit C.P. Koch, Ron H.J. Mathijssen & Stijn L.W. Koolen. (2021) Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain. Cancers 13:11, pages 2768.
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Yuqin Yu, Dapeng Li, Ji’an Duan, Hongshuang Xu, Li Li, Dengwu Tan & Hong Yan. (2020) The pro- and anti-cancer effects of oxycodone are associated with epithelial growth factor receptor level in cancer cells. Bioscience Reports 40:2.
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Mari Kinnunen, Hannu Kokki, Heidi Hautajärvi, Juulia Lantto, Juha Räsänen, Hanna‐Marja Voipio & Merja Kokki. (2019) Oxycodone concentrations in the central nervous system and cerebrospinal fluid after epidural administration to the pregnant ewe. Basic & Clinical Pharmacology & Toxicology 125:5, pages 430-438.
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