Advanced search
Publication Cover
Expert Opinion on Drug Delivery Volume 16, 2019 - Issue 10
Submit an article Journal homepage
458
Views
18
CrossRef citations to date
0
Altmetric
Meta-opinion

A meta-opinion: cannabinoids delivered to oral mucosa by a spray for systemic absorption are rather ingested into gastro-intestinal tract: the influences of fed / fasting states

Constantin ItinSchool of Pharmacy, the Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelView further author information
,
Abraham J DombSchool of Pharmacy, the Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelView further author information
&
Amnon HoffmanSchool of Pharmacy, the Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelCorrespondence[email protected]
View further author information
Pages 1031-1035 | Received 03 Jun 2019, Accepted 06 Aug 2019, Published online: 12 Aug 2019

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Kelly Light & Salwa Karboune. (2022) Emulsion, hydrogel and emulgel systems and novel applications in cannabinoid delivery: a review. Critical Reviews in Food Science and Nutrition 62:29, pages 8199-8229.
Read now
Ayala Bar-Hai, Abraham J. Domb & Amnon Hoffman. (2022) Strategies for enhancing the oral bioavailability of cannabinoids. Expert Opinion on Drug Metabolism & Toxicology 18:5, pages 313-322.
Read now

Articles from other publishers (16)

Md Moniruzzaman, Taskeen Iqbal Janjua, Jennifer H. Martin, Jakob Begun & Amirali Popat. (2024) Cannabidiol - Help and hype in targeting mucosal diseases. Journal of Controlled Release 365, pages 530-543.
Crossref
Olivia Sen, Sreejan Manna, Gouranga Nandi, Subrata Jana & Sougata Jana. (2023) Recent advances in alginate based gastroretentive technologies for drug delivery applications. Medicine in Novel Technology and Devices 18, pages 100236.
Crossref
Grace Tsz Yan Yau, Waiting Tai, Jonathon Carl Arnold, Hak-Kim Chan & Philip Chi Lip Kwok. (2023) Cannabidiol for the Treatment of Brain Disorders: Therapeutic Potential and Routes of Administration. Pharmaceutical Research 40:5, pages 1087-1114.
Crossref
Christopher M. Melén, Magali MerrienAgata M. WasikBirgitta SanderBjörn Engelbrekt WahlinGeorgios PanagiotisOlof Beck. (2023) Δ 9 -THC and CBD in Plasma, Oral Fluid, Exhaled Breath, and Urine from 23 Patients Administered Sativex . Cannabis and Cannabinoid Research.
Crossref
Giorgia della Rocca, Fabiola Paoletti, Maria Beatrice Conti, Roberta Galarini, Elisabetta Chiaradia, Monica Sforna, Cecilia Dall'Aglio, Angela Polisca & Alessandra Di Salvo. (2023) Pharmacokinetics of cannabidiol following single oral and oral transmucosal administration in dogs. Frontiers in Veterinary Science 9.
Crossref
Guillermo Moreno-Sanz, Alvaro Madiedo, Michael Lynskey & Matthew R. D. Brown. (2022) “Flower Power”: Controlled Inhalation of THC-Predominant Cannabis Flos Improves Health-Related Quality of Life and Symptoms of Chronic Pain and Anxiety in Eligible UK Patients. Biomedicines 10:10, pages 2576.
Crossref
Peera Tabboon, Thaned Pongjanyakul, Ekapol Limpongsa & Napaphak Jaipakdee. (2022) Mucosal Delivery of Cannabidiol: Influence of Vehicles and Enhancers. Pharmaceutics 14:8, pages 1687.
Crossref
Dakir Polidoro, Robin Temmerman, Mathias Devreese, Marios Charalambous, Luc Van Ham, Ine Cornelis, Bart J. G. Broeckx, Paul J. J. Mandigers, Andrea Fischer, Jan Storch & Sofie F. M. Bhatti. (2022) Pharmacokinetics of Cannabidiol Following Intranasal, Intrarectal, and Oral Administration in Healthy Dogs. Frontiers in Veterinary Science 9.
Crossref
Thope Moqejwa, Thashree Marimuthu, Pierre P. D. Kondiah & Yahya E. Choonara. (2022) Development of Stable Nano-Sized Transfersomes as a Rectal Colloid for Enhanced Delivery of Cannabidiol. Pharmaceutics 14:4, pages 703.
Crossref
Supratim Das, Sukhbir Kaur & Vineet Kumar Rai. (2021) Gastro-retentive drug delivery systems: a recent update on clinical pertinence and drug delivery. Drug Delivery and Translational Research 11:5, pages 1849-1877.
Crossref
Chiung-Wei Huang, Pi-Chen Lin, Jian-Lin Chen & Ming-Jen Lee. (2021) Cannabidiol Selectively Binds to the Voltage-Gated Sodium Channel Nav1.4 in Its Slow-Inactivated State and Inhibits Sodium Current. Biomedicines 9:9, pages 1141.
Crossref
Constantin Itin, Rinat Komargodski, Dinorah Barasch, Abraham J. Domb & Amnon Hoffman. (2021) Prolonged Delivery of Apomorphine Through the Buccal Mucosa, Towards a Noninvasive Sustained Administration Method in Parkinson's Disease: In Vivo Investigations in Pigs. Journal of Pharmaceutical Sciences 110:4, pages 1824-1833.
Crossref
Joseph J. Wakshlag, Wayne S. Schwark, Kelly A. Deabold, Bryce N. Talsma, Stephen Cital, Alex Lyubimov, Asif Iqbal & Alexander Zakharov. (2020) Pharmacokinetics of Cannabidiol, Cannabidiolic Acid, Δ9-Tetrahydrocannabinol, Tetrahydrocannabinolic Acid and Related Metabolites in Canine Serum After Dosing With Three Oral Forms of Hemp Extract. Frontiers in Veterinary Science 7.
Crossref
Constantin Itin, Rinat Komargodski, Abraham J. Domb & Amnon Hoffman. (2020) Controlled Delivery of Apomorphine Through Buccal Mucosa, Towards a Noninvasive Administration Method in Parkinson's Disease: A Preclinical Mechanistic Study. Journal of Pharmaceutical Sciences 109:9, pages 2729-2734.
Crossref
Sophie Anne Millar, Ryan Francis Maguire, Andrew Stephen Yates & Saoirse Elizabeth O’Sullivan. (2020) Towards Better Delivery of Cannabidiol (CBD). Pharmaceuticals 13:9, pages 219.
Crossref
Constantin Itin, Dinorah Barasch, Abraham J. Domb & Amnon Hoffman. (2020) Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol. International Journal of Pharmaceutics 581, pages 119276.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.