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Expert Opinion on Drug Delivery Volume 16, 2019 - Issue 10
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Original Research

Preparation of sterile long-acting injectable medroxyprogesterone acetate microcrystals based on anti-solvent precipitation and crystal habit control

Rong SunDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
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Yuting GuoDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China; Technical support department, Livzon Group Livzon Pharmaceutical Factory, Zhuhai, Guangdong, PR ChinaView further author information
,
Na YinDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
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Jiaojiao YinDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
,
Tian YinSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
,
Haibing HeDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
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Jingxin GouDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
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Yu ZhangDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0978-2363View further author information
ORCID Icon &
Xing TangDepartment of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaView further author information
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Pages 1133-1144 | Received 03 May 2019, Accepted 28 Aug 2019, Published online: 16 Sep 2019

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Yue Wang, Xinyi Tan, Xinyu Fan, Linxuan Zhao, Shuhang Wang, Haibing He, Tian Yin, Yu Zhang, Xing Tang, Lingyan Jian, Jian Jin & Jingxin Gou. (2021) Current strategies for oral delivery of BCS IV drug nanocrystals: challenges, solutions and future trends. Expert Opinion on Drug Delivery 18:9, pages 1211-1228.
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Articles from other publishers (6)

Siyu Pu & Kunn Hadinoto. (2024) Habit modification in pharmaceutical crystallization: A review. Chemical Engineering Research and Design 201, pages 45-66.
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Vy Thi Thanh Nguyen, Nicolas Darville & An Vermeulen. (2022) Pharmacokinetics of Long-Acting Aqueous Nano-/Microsuspensions After Intramuscular Administration in Different Animal Species and Humans—a Review. The AAPS Journal 25:1.
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Jingxin Gou, Silin Wang, Xu Li, Tian Yin, Haibing He, Yu Zhang, Xing Tang, Wei Xiao & Zhenzhong Wang. (2022) Reduced In vivo burst release of ginkgolide B microcrystals achieved by polymeric H+ depot. Journal of Drug Delivery Science and Technology 67, pages 102963.
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Myoung Jin Ho, Min Young Jeong, Hoe Taek Jeong, Min Seob Kim, Hyun Jin Park, Dong Yoon Kim, Hyo Chun Lee, Woo Heon Song, Chang Hyun Kim, Choong Hyun Lee, Young Wook Choi, Yong Seok Choi, Young Taek Han & Myung Joo Kang. (2022) Effect of particle size on in vivo performances of long-acting injectable drug suspension. Journal of Controlled Release 341, pages 533-547.
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Xueting Guo, Maolian Zhang, Yibin Guo, Hao Liu, Bing Yang, Jingxin Gou, Tian Yin, Yu Zhang, Haibing He, Dongchun Liu & Xing Tang. (2022) Impact of jet pulverization and wet milling techniques on properties of aripiprazole long-acting injection and absorption mechanism research in vivo. International Journal of Pharmaceutics 612, pages 121300.
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Junxiong Zhu, Chenggui Zhang, Jialin Jia, Hong Wang, Huijie Leng, Yingsheng Xu, Cuishuan Wu, Qiang Zhang & Chunli Song. (2020) Osteogenic effects in a rat osteoporosis model and femur defect model by simvastatin microcrystals. Annals of the New York Academy of Sciences 1487:1, pages 31-42.
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