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Expert Opinion on Drug Delivery Volume 18, 2021 - Issue 6
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Review

Topical preservative-free ophthalmic treatments: an unmet clinical need

Michele Figusa Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2243-9033
ORCID Icon,
Luca Agnifilib Ophthalmology Clinic, Department of Medicine and Aging Science, University G. D’Annunzio of Chieti-Pescara, Chieti, Italy
,
Manuela Lanzinib Ophthalmology Clinic, Department of Medicine and Aging Science, University G. D’Annunzio of Chieti-Pescara, Chieti, Italy
,
Lorenza Bresciab Ophthalmology Clinic, Department of Medicine and Aging Science, University G. D’Annunzio of Chieti-Pescara, Chieti, ItalyORCID Iconhttps://orcid.org/0000-0001-7874-7794
ORCID Icon,
Francesco Sartinia Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy
,
Leonardo Mastropasquab Ophthalmology Clinic, Department of Medicine and Aging Science, University G. D’Annunzio of Chieti-Pescara, Chieti, Italy
&
Chiara Posarellia Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, ItalyORCID Iconhttps://orcid.org/0000-0003-0222-5177
ORCID Icon show all
Pages 655-672 | Received 19 Jul 2020, Accepted 02 Dec 2020, Published online: 16 Dec 2020

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Christina Scelfo, Reem H. ElSheikh, Muhammad M. Shamim, Javaneh Abbasian, Alireza Ghaffarieh & Abdelrahman M. Elhusseiny. (2023) Ocular Surface Disease in Glaucoma Patients. Current Eye Research 48:3, pages 219-230.
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Francesco Oddone, Vincenzo Scorcia, Michele Iester, Dario Sisto, Stefano De Cilla, Paolo Bettin, Carlo Cagini, Michele Figus, Giorgio Marchini, Luca Rossetti, Gemma Rossi, Tommaso Salgarello, Gian Luca Scuderi & Giovanni Staurenghi. (2022) Treatment of Open-Angle Glaucoma and Ocular Hypertension with the Fixed-Dose Combination of Preservative-Free Tafluprost/Timolol: Clinical Outcomes from Ophthalmology Clinics in Italy. Clinical Ophthalmology 16, pages 1707-1719.
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Gábor Holló, Andreas Katsanos, Konstadinos G. Boboridis, Murat Irkec & Anastasios G. Konstas. (2021) Letter to the editor: ‘topical preservative-free ophthalmic treatments an unmet clinical need’. Expert Opinion on Drug Delivery 18:4, pages 527-529.
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Anastasios G. Konstas, Antoine Labbé, Andreas Katsanos, Frances Meier-Gibbons, Murat Irkec, Konstadinos G. Boboridis, Gábor Holló, Julián García-Feijoo, Gordon N. Dutton & Christophe Baudouin. (2021) The treatment of glaucoma using topical preservative-free agents: an evaluation of safety and tolerability. Expert Opinion on Drug Safety 20:4, pages 453-466.
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Articles from other publishers (8)

Anastasios-Georgios Konstas, Konstadinos G. Boboridis, Georgios P. Athanasopoulos, Anna-Bettina Haidich, Irini C. Voudouragkaki, Eirini Pagkalidou, Andreas Katsanos & L. Jay Katz. (2023) Changing from preserved, to preservative-free cyclosporine 0.1% enhanced triple glaucoma therapy: impact on ocular surface disease—a randomized controlled trial. Eye 37:17, pages 3666-3674.
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Michele Figus, Matteo Sacchi, Gemma Caterina Rossi, Silvia Babighian, José Manuel Benitez Del Castillo, Laura de Polo, Eugenio Melchionda & Chiara Posarelli. (2023) Ocular surface and glaucoma, a mutual relationship. Practical suggestions for classification and management. European Journal of Ophthalmology.
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Christoph Tappeiner, Arnd Heiligenhaus, Joerg P. Halter, Elisabetta Miserocchi, Francesco Bandello & David Goldblum. (2023) Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease. Frontiers in Medicine 10.
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Nupur Vasdev, Nakshatra Chaudhari, Suryanarayana Polaka, Kuldeep Rajpoot, Piyush Gondaliya, Adil Ali Sayyed, Pinaki Sengupta & Rakesh Kumar Tekade. (2023) Current progress in preservative-free topical ophthalmic formulations. Journal of Drug Delivery Science and Technology 79, pages 103996.
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Kassahun Alula Akulo, Terin Adali, Mthabisi Talent George Moyo & Tulin Bodamyali. (2022) Intravitreal Injectable Hydrogels for Sustained Drug Delivery in Glaucoma Treatment and Therapy. Polymers 14:12, pages 2359.
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Marion Barrieu, Philip Chennell, Mouloud Yessaad, Yassine Bouattour, Mathieu Wasiak, Mireille Jouannet, Yoann Le Basle & Valérie Sautou. (2022) Physicochemical Stability of a Novel Tacrolimus Ophthalmic Formulation for the Treatment of Ophthalmic Inflammatory Diseases. Pharmaceutics 14:1, pages 118.
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Bharti Gupta, Varsha Mishra, Sankalp Gharat, Munira Momin & Abdelwahab Omri. (2021) Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems. Pharmaceuticals 14:11, pages 1201.
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Francesco Sartini, Martina Menchini, Chiara Posarelli, Giamberto Casini & Michele Figus. (2021) In Vivo Efficacy of Contact Lens Drug-Delivery Systems in Glaucoma Management. A Systematic Review. Applied Sciences 11:2, pages 724.
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