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Expert Opinion on Drug Metabolism & Toxicology Volume 12, 2016 - Issue 9
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Drug Evaluation

Pharmacodynamic assessment of apremilast for the treatment of moderate-to-severe plaque psoriasis

Luca BianchiDepartment of Systems Medicine, Division of Dermatology, University of Rome Tor Vergata, Rome, ItalyView further author information
,
Ester Del DucaDepartment of Systems Medicine, Division of Dermatology, University of Rome Tor Vergata, Rome, ItalyCorrespondence[email protected]
View further author information
,
Marco RomanelliDivision of Dermatology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, ItalyView further author information
,
Rosita SaracenoDepartment of Systems Medicine, Division of Dermatology, University of Rome Tor Vergata, Rome, ItalyView further author information
,
Sergio ChimentiDepartment of Systems Medicine, Division of Dermatology, University of Rome Tor Vergata, Rome, ItalyView further author information
&
Andrea ChiricozziDivision of Dermatology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, ItalyView further author information
Pages 1121-1128 | Received 17 Mar 2016, Accepted 22 Jun 2016, Published online: 14 Jul 2016

Citations (14)

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Celina Dubin, Ester Del Duca & Emma Guttman-Yassky. (2020) Drugs for the Treatment of Chronic Hand Eczema: Successes and Key Challenges. Therapeutics and Clinical Risk Management 16, pages 1319-1332.
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Masutaka Furue, Takafumi Kadono, Gaku Tsuji & Takeshi Nakahara. (2017) Topical E6005/RVT-501, a novel phosphodiesterase 4 inhibitor, for the treatment of atopic dermatitis. Expert Opinion on Investigational Drugs 26:12, pages 1403-1408.
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A. Dattola, E. Del Duca, R. Saraceno, T. Gramiccia & L. Bianchi. (2017) Safety evaluation of apremilast for the treatment of psoriasis. Expert Opinion on Drug Safety 16:3, pages 381-385.
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Articles from other publishers (11)

Zoltán-István Szabó, Beáta-Mária Benkő, Ágnes Bartalis-Fábián, Róbert Iványi, Erzsébet Varga, Levente Szőcs & Gergő Tóth. (2023) Chiral Separation of Apremilast by Capillary Electrophoresis Using Succinyl-β-Cyclodextrin—Reversal of Enantiomer Elution Order by Cationic Capillary Coating. Molecules 28:8, pages 3310.
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Yashika Tomar, Srividya Gorantla & Gautam Singhvi. (2023) Insight into the pivotal role of signaling pathways in psoriasis pathogenesis, potential therapeutic molecules and drug delivery approaches. Drug Discovery Today 28:2, pages 103465.
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Kazuki Yatsuzuka, Masamoto Murakami, Satoshi Yoshida, Ryo Utsunomiya, Takao Watanabe & Koji Sayama. (2021) Successful treatment of psoriasis vulgaris with apremilast in a patient with decompensated cirrhosis. The Journal of Dermatology 49:4.
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Hee J. Kim, Ester Del Duca, Ana B. Pavel, Giselle K. Singer, Brian J. Abittan, Margot A. Chima, Grace Kimmel, Jennifer Bares, Danielle Baum, Matthew Gagliotti, Jordan Genece, Justin Chu, Mark G. Lebwohl & Emma Guttman-Yassky. (2022) Apremilast and narrowband ultraviolet B combination therapy suppresses Th17 axis and promotes melanogenesis in vitiligo skin: a randomized, split-body, pilot study in skin types IV–VI. Archives of Dermatological Research 315:2, pages 215-221.
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Heng Li, Yao Zhang, Moting Liu, Chen Fan, Chunlan Feng, Qiukai Lu, Caigui Xiang, Huimin Lu, Xiaoqian Yang, Bing Wu, Duowu Zou & Wei Tang. (2022) Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis. Acta Pharmaceutica Sinica B 12:1, pages 228-245.
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Paulo Sarango-Granda, Marcelle Silva-Abreu, Ana Calpena, Lyda Halbaut, María-José Fábrega, María Rodríguez-Lagunas, Natalia Díaz-Garrido, Josefa Badia & Lupe Espinoza. (2020) Apremilast Microemulsion as Topical Therapy for Local Inflammation: Design, Characterization and Efficacy Evaluation. Pharmaceuticals 13:12, pages 484.
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Ester Del Duca, Paola Morelli, Luigi Bennardo, Cosimo Di Raimondo & Steven Paul Nisticò. (2020) Cytokine Pathways and Investigational Target Therapies in Hidradenitis Suppurativa. International Journal of Molecular Sciences 21:22, pages 8436.
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Christos Tziotzios, Timothy Brier, John Y.W. Lee, Ryo Saito, Chao-Kai Hsu, Kapil Bhargava, Catherine M. Stefanato, David A. Fenton & John A. McGrath. (2018) Lichen planus and lichenoid dermatoses. Journal of the American Academy of Dermatology 79:5, pages 807-818.
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Heng Li, Jianping Zuo & Wei Tang. (2018) Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases. Frontiers in Pharmacology 9.
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Tiago Torres & Luis Puig. (2017) Apremilast: A Novel Oral Treatment for Psoriasis and Psoriatic Arthritis. American Journal of Clinical Dermatology 19:1, pages 23-32.
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Maria Relvas & Tiago Torres. (2017) Pediatric Psoriasis. American Journal of Clinical Dermatology 18:6, pages 797-811.
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