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Expert Opinion on Drug Metabolism & Toxicology Volume 14, 2018 - Issue 12
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Review

Pharmacogenetics of treatments for inflammatory bowel disease

Marianna LucafòExperimental and Clinical Pharmacology Unit, National Cancer Institute – Centro di Riferimento Oncologico, Aviano, Italy;Institute for Maternal and Child Health IRCCS Burlo Garofolo, Diagnostics Department Trieste, ItalyView further author information
,
Raffaella FrancaInstitute for Maternal and Child Health IRCCS Burlo Garofolo, Diagnostics Department Trieste, Italy;Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, ItalyView further author information
,
Davide SelvestrelPhD School in Science of Reproduction and Development, University of Trieste, Trieste, ItalyView further author information
,
Debora CurciPhD School in Science of Reproduction and Development, University of Trieste, Trieste, ItalyView further author information
,
Letizia PugnettiPhD School in Science of Reproduction and Development, University of Trieste, Trieste, ItalyView further author information
,
Giuliana DecortiInstitute for Maternal and Child Health IRCCS Burlo Garofolo, Diagnostics Department Trieste, Italy;Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, ItalyView further author information
&
Gabriele StoccoDepartment of Life Sciences, University of Trieste, Trieste, ItalyCorrespondence[email protected]
View further author information
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Pages 1209-1223 | Received 27 Aug 2018, Accepted 20 Nov 2018, Published online: 03 Dec 2018

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R Franca, S Braidotti, G Stocco & G Decorti. (2021) Understanding thiopurine methyltransferase polymorphisms for the targeted treatment of hematologic malignancies. Expert Opinion on Drug Metabolism & Toxicology 17:10, pages 1187-1198.
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Raffaella Franca, Debora Curci, Marianna Lucafò, Giuliana Decorti & Gabriele Stocco. (2019) Therapeutic drug monitoring to improve outcome of anti-TNF drugs in pediatric inflammatory bowel disease. Expert Opinion on Drug Metabolism & Toxicology 15:7, pages 527-539.
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Articles from other publishers (21)

Letizia Pugnetti, Debora Curci, Carlotta Bidoli, Marco Gerdol, Fulvio Celsi, Sara Renzo, Monica Paci, Sara Lega, Martina Nonnis, Alessandra Maestro, Liza Vecchi Brumatti, Paolo Lionetti, Alberto Pallavicini, Danilo Licastro, Paolo Edomi, Giuliana Decorti, Gabriele Stocco, Marianna Lucafò & Matteo Bramuzzo. (2023) Gene expression profiling in white blood cells reveals new insights into the molecular mechanisms of thalidomide in children with inflammatory bowel disease. Biomedicine & Pharmacotherapy 164, pages 114927.
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Stefania Cheli, Diego Savino, Annalisa De Silvestri, Lorenzo Norsa, Naire Sansotta, Francesca Penagini, Dario Dilillo, Roberto Panceri, Dario Cattaneo, Emilio Clementi & Giovanna Zuin. (2023) One year of experience with combined pharmacokinetic/pharmacogenetic monitoring of anti-TNF alpha agents: a retrospective study. The Pharmacogenomics Journal.
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Konstantinos Papamichael, Gabriele Stocco & Ainhoa Ruiz del Agua. (2023) Challenges in Therapeutic Drug Monitoring: Optimizing Biological Treatments in Patients With Inflammatory Bowel Disease and Other Immune-Mediated Inflammatory Diseases. Therapeutic Drug Monitoring Publish Ahead of Print.
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Giulia Zudeh, Raffaella Franca, Marianna Lucafò, Erik J Bonten, Matteo Bramuzzo, Riccardo Sgarra, Cristina Lagatolla, Martina Franzin, William E Evans, Giuliana Decorti & Gabriele Stocco. (2023) PACSIN2 as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells . Life Science Alliance 6:3, pages e202201610.
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Davide Selvestrel, Gabriele Stocco, Marina Aloi, Serena Arrigo, Sabrina Cardile, Erika Cecchin, Mauro Congia, Debora Curci, Simona Gatti, Francesco Graziano, Carl D. Langefeld, Marianna Lucafò, Stefano Martelossi, Massimo Martinelli, Sofia Pagarin, Luca Scarallo, Elisabetta Francesca Stacul, Caterina Strisciuglio, Susan Thompson, Giovanna Zuin, Giuliana Decorti & Matteo Bramuzzo. (2023) DNA methylation of the TPMT gene and azathioprine pharmacokinetics in children with very early onset inflammatory bowel disease. Biomedicine & Pharmacotherapy 157, pages 113901.
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Mansour A. Alghamdi, Laith N. AL-Eitan, Hanan A. Aljamal, Ayed A. Shati & Mohammed A. Alshehri. (2022) Genetic association of IL2RA, IL17RA, IL23R, and IL31RA single nucleotide polymorphisms with alopecia areata. Saudi Journal of Biological Sciences 29:11, pages 103460.
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Marjolein Drent, Naomi T. Jessurun, Petal A. Wijnen, Otto Bekers & Aalt Bast. (2022) Drug-induced comorbidities in patients with sarcoidosis. Current Opinion in Pulmonary Medicine 28:5, pages 468-477.
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Jerko Štambuk, Frano Vučković, Siniša Habazin, Maja Hanić, Mislav Novokmet, Susanna Nikolaus, Florian Tran, Stefan Schreiber, Andre Franke, Philip Rosenstiel, Gordan Lauc, Konrad Aden & Marija Pezer. (2022) Distinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases. International Journal of Molecular Sciences 23:15, pages 8473.
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Marianna Lucafò, Antonella Muzzo, Martina Marcuzzi, Lorenzo Giorio, Giuliana Decorti & Gabriele Stocco. (2022) Patient-derived organoids for therapy personalization in inflammatory bowel diseases. World Journal of Gastroenterology 28:24, pages 2636-2653.
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Brian D. Friend & Gary J. Schiller. (2022) Beyond steroids: A systematic review and proposed solutions to managing acute graft-versus-host disease in adolescents and young adults. Blood Reviews 52, pages 100886.
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Ji Young Chang & Jae Hee Cheon. (2021) Pharmacogenetics-based personalized treatment in patients with inflammatory bowel disease: A review. Precision and Future Medicine 5:4, pages 151-163.
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Debora Curci, Marianna Lucafò, Adriana Cifù, Martina Fabris, Matteo Bramuzzo, Stefano Martelossi, Raffaella Franca, Giuliana Decorti & Gabriele Stocco. (2021) Pharmacogenetic variants of infliximab response in young patients with inflammatory bowel disease. Clinical and Translational Science 14:6, pages 2184-2192.
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Marianna Lucafò, Matteo Bramuzzo, Davide Selvestrel, Prisca Da Lozzo, Giuliana Decorti & Gabriele Stocco. (2021) Gender May Influence the Immunosuppressive Actions of Prednisone in Young Patients With Inflammatory Bowel Disease. Frontiers in Immunology 12.
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Daniel J. MulderSam KhaloueiNeil WarnerClaudia Gonzaga-Jauregui, Peter C. ChurchThomas D. WaltersArun K. RamaniAnne M. GriffithsIris CohnAleixo M. Muise. (2020) Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease. Clinical and Translational Gastroenterology 11:12, pages e00263.
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Meng-meng Ning, Wen-ji Yang, Wen-bo Guan, Yi-pei Gu, Ying Feng & Ying Leng. (2020) Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2. Acta Pharmacologica Sinica 41:11, pages 1446-1456.
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Marianna Lucafò, Martina Franzin, Cristina Lagatolla, Raffaella Franca, Matteo Bramuzzo, Gabriele Stocco & Giuliana Decorti. (2019) Emerging Insights on the Interaction Between Anticancer and Immunosuppressant Drugs and Intestinal Microbiota in Pediatric Patients. Clinical and Translational Science 13:2, pages 238-259.
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Reed E. Pyeritz. 2020. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics 485 505 .
Clément Anfray, Francesco Mainini & Fernando Torres Andón. 2020. Colloids for Nanobiotechnology - Synthesis, Characterization and Potential Applications. Colloids for Nanobiotechnology - Synthesis, Characterization and Potential Applications 265 306 .
Zhen Zeng, Arjudeb Mukherjee & Hu Zhang. (2019) From Genetics to Epigenetics, Roles of Epigenetics in Inflammatory Bowel Disease. Frontiers in Genetics 10.
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Marianna Lucafò, Gabriele Stocco, Stefano Martelossi, Diego Favretto, Raffaella Franca, Noelia Malusà, Angela Lora, Matteo Bramuzzo, Samuele Naviglio, Erika Cecchin, Giuseppe Toffoli, Alessandro Ventura & Giuliana Decorti. (2019) Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants. Genes 10:4, pages 277.
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Gian Tenore, Ester Pagano, Stefania Lama, Daniela Vanacore, Salvatore Di Maro, Maria Maisto, Raffaele Capasso, Francesco Merlino, Francesca Borrelli, Paola Stiuso & Ettore Novellino. (2019) Intestinal Anti-Inflammatory Effect of a Peptide Derived from Gastrointestinal Digestion of Buffalo (Bubalus bubalis) Mozzarella Cheese. Nutrients 11:3, pages 610.
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