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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 1
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Review

Application of human pluripotent stem cells and pluripotent stem cell-derived cellular models for assessing drug toxicity

Ágota ApátiInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryView further author information
,
Nóra VargaInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryView further author information
,
Tünde BereczInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryView further author information
,
Zsuzsa ErdeiInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryView further author information
,
László HomolyaInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryORCID Iconhttp://orcid.org/0000-0003-1639-8140View further author information
ORCID Icon &
Balázs SarkadiInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, HungaryCorrespondence[email protected]
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Pages 61-75 | Received 03 Sep 2018, Accepted 07 Dec 2018, Published online: 17 Dec 2018

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I Gede Putu Supadmanaba, Annalisa Comandatore, Luca Morelli, Elisa Giovannetti & Tonny Lagerweij. (2021) Organotypic-liver slide culture systems to explore the role of extracellular vesicles in pancreatic cancer metastatic behavior and guide new therapeutic approaches. Expert Opinion on Drug Metabolism & Toxicology 17:8, pages 937-946.
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Sarah D. Burnett, Alexander D Blanchette, Weihsueh A. Chiu & Ivan Rusyn. (2021) Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization. Expert Opinion on Drug Metabolism & Toxicology 17:8, pages 887-902.
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Articles from other publishers (9)

Cátia D. Correia, Anita Ferreira, Mónica T. Fernandes, Bárbara M. Silva, Filipa Esteves, Helena S. Leitão, José Bragança & Sofia M. Calado. (2023) Human Stem Cells for Cardiac Disease Modeling and Preclinical and Clinical Applications—Are We on the Road to Success?. Cells 12:13, pages 1727.
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Jinping Gan, Brad Bolon, Terry Van Vleet & Charles Wood. 2022. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 925 966 .
Sarah D. Burnett, Alexander D. Blanchette, Weihsueh A. Chiu & Ivan Rusyn. (2021) Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors. Chemical Research in Toxicology 34:9, pages 2110-2124.
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Rick Wertenbroek, Yann Thoma, Flavio Maurizio Mor, Sara Grassi, Marc Olivier Heuschkel, Adrien Roux & Luc Stoppini. (2021) SpikeOnChip : A Custom Embedded Platform for Neuronal Activity Recording and Analysis. IEEE Transactions on Biomedical Circuits and Systems 15:4, pages 743-755.
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Uzair Ahmed, Rashid Ahmed, Muhammad Shareef Masoud, Muhammad Tariq, Usman Ali Ashfaq, Robin Augustine & Anwarul Hasan. (2021) Stem cells based in vitro models: trends and prospects in biomaterials cytotoxicity studies. Biomedical Materials 16:4, pages 042003.
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Passley Hargrove-Grimes, Lucie A Low & Danilo A Tagle. (2021) Microphysiological systems: What it takes for community adoption. Experimental Biology and Medicine 246:12, pages 1435-1446.
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Ana Sofia Martins Serras, Madalena Zincke dos Reis Fernandes Cipriano, Pedro Miguel da Graça Silva & Joana Paiva Gomes Miranda. 2021. Novel Perspectives of Stem Cell Manufacturing and Therapies. Novel Perspectives of Stem Cell Manufacturing and Therapies.
Ellen Fritsche, Thomas Haarmann‐Stemmann, Julia Kapr, Saskia Galanjuk, Julia Hartmann, Peter R. Mertens, Angela A. M. Kämpfer, Roel P. F. Schins, Julia Tigges & Katharina Koch. (2020) Stem Cells for Next Level Toxicity Testing in the 21st Century. Small 17:15.
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Jian Jiang, Charlie D. Pieterman, Gökhan Ertaylan, Ralf L. M. Peeters & Theo M. C. M. de Kok. (2019) The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro. Archives of Toxicology 93:11, pages 3067-3098.
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