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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 2
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Drug Evaluation

Pharmacokinetic drug evaluation of abemaciclib for advanced breast cancer

Marie RobertMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, FranceCorrespondence[email protected]
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,
Jean-Sébastien FrenelMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, FranceView further author information
,
Emmanuelle BourboulouxMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, FranceView further author information
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Dominique Berton RigaudMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, FranceView further author information
,
Anne PatsourisMedical Oncology, Institut de Cancérologie de l’Ouest, Paul Papin, Angers, FranceView further author information
,
Paule AugereauMedical Oncology, Institut de Cancérologie de l’Ouest, Paul Papin, Angers, FranceView further author information
,
Carole GourmelonMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, FranceView further author information
&
Mario CamponeMedical Oncology, Institut de Cancérologie de l’Ouest, René Gauducheau, St Herblain, France;Medical Oncology, Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), FranceView further author information
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Pages 85-91 | Received 20 Aug 2018, Accepted 13 Dec 2018, Published online: 05 Jan 2019

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Vittorio Gebbia, Maria Rosaria Valerio, Alberto Firenze & Paolo Vigneri. (2020) Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor. Expert Opinion on Drug Safety 19:8, pages 945-954.
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Articles from other publishers (3)

Ariana Soledad Poetto, Bianca Posocco, Martina Zanchetta, Sara Gagno, Marco Orleni, Giovanni Canil, Martina Alberti, Fabio Puglisi & Giuseppe Toffoli. (2022) “A new LC-MS/MS method for the simultaneous quantification of abemaciclib, its main active metabolites M2 and M20, and letrozole for therapeutic drug monitoring”. Journal of Chromatography B 1207, pages 123403.
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Disha Thakkar & Abhijeet S. Kate. (2020) Update on metabolism of abemaciclib: In silico , in vitro , and in vivo metabolite identification and characterization using high resolution mass spectrometry . Drug Testing and Analysis 12:3, pages 331-342.
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Emanuel Raschi & Fabrizio De Ponti. (2019) Strategies for Early Prediction and Timely Recognition of Drug-Induced Liver Injury: The Case of Cyclin-Dependent Kinase 4/6 Inhibitors. Frontiers in Pharmacology 10.
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