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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 3
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Review

Pharmacokinetic considerations for anti-epileptic drugs in children

Alberto VerrottiDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyCorrespondence[email protected]
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Giulia IapadreDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyView further author information
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Giulia Di DonatoDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyView further author information
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Ludovica Di FrancescoDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyView further author information
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Luca ZagaroliDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyView further author information
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Sara MatricardiChild Neurology and Psychiatry Unit, Children’s Hospital G. Salesi, Ancona, ItalyView further author information
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Vincenzo BelcastroNeurology Unit, S. Anna Hospital, Como, ItalyORCID Iconhttp://orcid.org/0000-0002-3416-2900View further author information
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Maria Laura IezziDepartment of Pediatrics, University of L’Aquila, L’Aquila, ItalyView further author information
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Pages 199-211 | Received 10 Nov 2018, Accepted 24 Jan 2019, Published online: 07 Feb 2019

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Eleonora Tulli, Giuseppe Di Cara, Giulia Iapadre, Pasquale Striano & Alberto Verrotti. (2021) An update on brivaracetam for the treatment of pediatric partial epilepsy. Expert Opinion on Pharmacotherapy 22:11, pages 1387-1395.
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Sara Matricardi, Francesca Felicia Operto, Giovanni Farello, Giangennaro Coppola & Alberto Verrotti. (2020) Withdrawal seizures: possible risk factors. Expert Review of Neurotherapeutics 20:7, pages 667-672.
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Cecilie Johannessen Landmark, Svein I. Johannessen & Philip N. Patsalos. (2020) Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 227-238.
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Shijin Xuan, Aline Oliveira da Silva de Barros, Rogério Chaffin Nunes, Eduardo Ricci-Junior, Ademir Xavier da Silva, Muhammad Sahid, Luciana Magalhaes Rebelo Alencar, Clenilton Costa dos Santos, Veronica Morandi, Frank Alexis, Surtaj H. Iram & Ralph Santos-Oliveira. (2020) Radioactive gold nanocluster (198-AuNCs) showed inhibitory effects on cancer cells lines. Artificial Cells, Nanomedicine, and Biotechnology 48:1, pages 1214-1221.
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Giovanna Cristiano de Gouveia, Bruno Pereira dos Santos, Cleofas Sates, Viviane Cristina Sebben, Sarah Eller, Marcelo Dutra Arbo & Tiago Franco de Oliveira. (2023) A simple approach for determination of plasmatic levels of carbamazepine and phenobarbital in poisoning cases using DLLME and liquid chromatography. Toxicologie Analytique et Clinique 35:4, pages 293-305.
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Shifeng Wei, Xingmeng Li, Han Wu, Qiang Zhang, Yun Wu, Zhigang Zhao, Shenghui Mei & Weixing Feng. (2023) UGT1A polymorphism rs4148324 associated with topiramate plasma concentration to dose ratio in children with epilepsy. Seizure: European Journal of Epilepsy.
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Umme Habeeba A. Pathan, Navapreetha Shetty, Safiya Anhar & Reshma Mayya. (2023) Peripheral visual field defect of vigabatrin in pediatric epilepsy: A review. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 59:1.
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Cecilie Johannessen Landmark, Sara Eyal, Margrete Larsen Burns, Valentina Franco & Svein I. Johannessen. (2023) Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring. Epileptic Disorders.
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Ayesha Safdar & Fatima Ismail. (2023) A comprehensive review on pharmacological applications and drug-induced toxicity of valproic acid. Saudi Pharmaceutical Journal 31:2, pages 265-278.
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Tayla Taynan Romão, Abraão Iuri Medeiros Angelim, Henrique Jannuzzelli Pires do Prado, Fernanda Veiga de Goes, Maria Elisa Paiva Pires, Rosiane da Silva Fontana, Lais de Carvalho Pires, Alexandre Ribeiro Fernandes & Isabella D'Andrea-Meira. (2022) Use of lacosamide in children: experience of a tertiary medical care center in Brazil. Arquivos de Neuro-Psiquiatria 80:11, pages 1090-1096.
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I Gusti Ngurah Made Suwarba, Anak Agung Ratna Purnama Santhi & Dewi Sutriani Mahalini. (2022) Correlation between Level of Serum Transaminases and Duration of Antiepileptic Drugs in Epilepsy Children in Sanglah Hospital. Open Access Macedonian Journal of Medical Sciences 10:B, pages 395-401.
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Gregory Fishberger, Nicole Natarelli, Dao Le, Deborah Liaw, Afrin Naz, Caroline Ward, Michael Young & Charles Preuss. 2022. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology 21 42 .
Brad Bolon, Lori A. Dostal & Robert H. Garman. (2021) Neuropathology Evaluation in Juvenile Toxicity Studies in Rodents: Comparison of Developmental Neurotoxicity Studies for Chemicals With Juvenile Animal Studies for Pediatric Pharmaceuticals. Toxicologic Pathology 49:8, pages 1405-1415.
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Huma Khan, Vaidehi Makwana, Sofia Nascimento dos Santos, Carlos Eduardo Bonacossa de Almeida, Ralph Santos-Oliveira & Sotiris Missailidis. (2021) Development, Characterization, and In Vivo Evaluation of a Novel Aptamer (Anti-MUC1/Y) for Breast Cancer Therapy. Pharmaceutics 13:8, pages 1239.
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Seth Kwabena Amponsah, Simon Yeboah, Kennedy Kwami Edem Kukuia, Benoit Banga N’guessan & Ofosua Adi-Dako. (2021) A Pharmacokinetic Evaluation of a Pectin-Based Oral Multiparticulate Matrix Carrier of Carbamazepine. Advances in Pharmacological and Pharmaceutical Sciences 2021, pages 1-7.
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Cecilie Johannessen Landmark, Katrine Heger, Caroline Lund, Margrete Larsen Burns, Marit Bjørnvold, Erik Sætre & Svein I. Johannessen. (2020) Pharmacokinetic Variability During Long-Term Therapeutic Drug Monitoring of Valproate, Clobazam, and Levetiracetam in Patients With Dravet Syndrome. Therapeutic Drug Monitoring 42:5, pages 744-753.
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Sara Matricardi, Giovanni Farello, Salvatore Savasta & Alberto Verrotti. (2019) Understanding Childhood Neuroimmune Diseases of the Central Nervous System. Frontiers in Pediatrics 7.
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