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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 4
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Review

Current understanding of pharmacogenetic implications of DNA damaging drugs used in osteosarcoma treatment

Claudia Maria HattingerPharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyView further author information
,
Maria Pia PatrizioPharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyView further author information
,
Silvia LuppiPharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyView further author information
,
Federica MagagnoliPharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyView further author information
,
Piero PicciLaboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyView further author information
&
Massimo SerraPharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, ItalyCorrespondence[email protected]
View further author information
Pages 299-311 | Received 19 Dec 2018, Accepted 26 Feb 2019, Published online: 18 Mar 2019

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Meng-Dan Zhao, Jun-Qin Li, Feng-Ying Chen, Wei Dong, Li-Juan Wen, Wei-Dong Fei, Xiao Zhang, Pei-Lei Yang, Xin-Mei Zhang & Cai-Hong Zheng. (2019) Co-Delivery of Curcumin and Paclitaxel by “Core-Shell” Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer. International Journal of Nanomedicine 14, pages 9453-9467.
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Claudia Maria Hattinger, Maria Pia Patrizio, Federica Magagnoli, Silvia Luppi & Massimo Serra. (2019) An update on emerging drugs in osteosarcoma: towards tailored therapies?. Expert Opinion on Emerging Drugs 24:3, pages 153-171.
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Articles from other publishers (8)

Roelof van Ewijk, Nikolas Herold, Fredrik Baecklund, Daniel Baumhoer, Kjetil Boye, Nathalie Gaspar, Semi B. Harrabi, Lianne M. Haveman, Stefanie Hecker-Nolting, Laura Hiemcke-Jiwa, Valentine Martin, Cristina Mata Fernández, Emanuela Palmerini, Michiel A.J. van de Sande, Sandra J. Strauss, Stefan S. Bielack & Leo Kager. (2023) European standard clinical practice recommendations for children and adolescents with primary and recurrent osteosarcoma. EJC Paediatric Oncology 2, pages 100029.
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Sara R. Martins-Neves, Gabriela Sampaio-Ribeiro & Célia M. F. Gomes. (2022) Chemoresistance-Related Stem Cell Signaling in Osteosarcoma and Its Plausible Contribution to Poor Therapeutic Response: A Discussion That Still Matters. International Journal of Molecular Sciences 23:19, pages 11416.
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Claudia Maria Hattinger, Maria Pia Patrizio, Leonardo Fantoni, Chiara Casotti, Chiara Riganti & Massimo Serra. (2021) Drug Resistance in Osteosarcoma: Emerging Biomarkers, Therapeutic Targets and Treatment Strategies. Cancers 13:12, pages 2878.
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Yu-Bao Gong, Shao-Jie Fu, Zheng-Ren Wei & Jian-Guo Liu. (2021) Predictive Study of the Active Ingredients and Potential Targets of Codonopsis pilosula for the Treatment of Osteosarcoma via Network Pharmacology. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-16.
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Anita K. Luu & Alicia M. Viloria-Petit. (2020) Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective. International Journal of Molecular Sciences 21:20, pages 7595.
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Ingrid Lilienthal & Nikolas Herold. (2020) Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies. International Journal of Molecular Sciences 21:18, pages 6885.
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Shailer B. MartinWilliam S. ReicheNicholas A. FifelskiAlexander J. SchultzSpencer J. StanfordAlexander A. MartinDanielle L. NackBernhard Radlwimmer, Michael P. BoyerElitsa A. Ananieva. (2020) Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling. Biochemical Journal 477:9, pages 1579-1599.
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Marilù Fanelli, Elisa Tavanti, Maria Pia Patrizio, Serena Vella, Amira Fernandez-Ramos, Federica Magagnoli, Silvia Luppi, Claudia Maria Hattinger & Massimo Serra. (2020) Cisplatin Resistance in Osteosarcoma: In vitro Validation of Candidate DNA Repair-Related Therapeutic Targets and Drugs for Tailored Treatments. Frontiers in Oncology 10.
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