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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 7
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Review

What “The Cancer Genome Atlas” database tells us about the role of ATP-binding cassette (ABC) proteins in chemoresistance to anticancer drugs

Oscar BrizExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, Spain;Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid, SpainView further author information
,
Laura Perez-SilvaExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, SpainView further author information
,
Ruba Al-AbdullaExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, SpainView further author information
,
Lorena AbeteDepartment of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Rome, ItalyView further author information
,
Maria ReviejoExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, SpainView further author information
,
Marta R. RomeroExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, Spain;Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid, SpainView further author information
&
Jose J.G. MarinExperimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, Spain;Center for the Study of Liver and Gastrointestinal Diseases (CIBERehd), Carlos III National Institute of Health, Madrid, SpainCorrespondence[email protected]
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Pages 577-593 | Received 14 Feb 2019, Accepted 10 Jun 2019, Published online: 23 Jun 2019

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Fucheng Meng, Yafei Xiao, Longxiang Xie, Qiao Liu & Keli Qian. (2021) Diagnostic and prognostic value of ABC transporter family member ABCG1 gene in clear cell renal cell carcinoma. Channels 15:1, pages 375-385.
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Articles from other publishers (20)

Yichen Tian, Yongrong Lei, Yani Wang, Jiejuan Lai, Jianhua Wang & Feng Xia. (2023) Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review). International Journal of Oncology 63:5.
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Elisabetta Teodori, Laura Braconi, Dina Manetti, Maria Novella Romanelli & Silvia Dei. (2022) The Tetrahydroisoquinoline Scaffold in ABC Transporter Inhibitors that Act as Multidrug Resistance (MDR) Reversers. Current Topics in Medicinal Chemistry 22:31, pages 2535-2569.
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Shuangying Li, Liangliang Wang, Yuanyuan Wang, Changyi Zhang, Zhenya Hong & Zhiqiang Han. (2022) The synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment. Journal of Hematology & Oncology 15:1.
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Bin Xi, Fang-Zhou Luo, Bin He, Fang Wang, Ze-Kuan Li, Ming-Chun Lai & Shu-Sen Zheng. (2022) High nuclear ABCG1 expression is a poor predictor for hepatocellular carcinoma patient survival. Hepatobiliary & Pancreatic Diseases International 21:4, pages 370-377.
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Jose Marin, Maria Monte, Rocio Macias, Marta Romero, Elisa Herraez, Maitane Asensio, Sara Ortiz-Rivero, Candela Cives-Losada, Silvia Di Giacomo, Javier Gonzalez-Gallego, Jose Mauriz, Thomas Efferth & Oscar Briz. (2022) Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers. Cancers 14:14, pages 3524.
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Peilong Bu, Yafei Xiao, Shaowen Hu, Xiaowei Jiang, Cong Tan, Mengyuan Qiu, Wanting Huang, Mengmeng Li, Quanying Li & Changjiang Qin. (2022) Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer. Journal of Oncology 2022, pages 1-14.
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Rui Liu, Yurong Song, Chenxi Li, Zhengjia Zhang, Zeyu Xue, Qingcai Huang, Liuchunyang Yu, Dongjie Zhu, Zhiwen Cao, Aiping Lu, Cheng Lu & Yuanyan Liu. (2022) The naturally occurring flavonoid nobiletin reverses methotrexate resistance via inhibition of P-glycoprotein synthesis. Journal of Biological Chemistry 298:4, pages 101756.
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Daniel T. Infield, Kerry M. Strickland, Amit Gaggar & Nael A. McCarty. (2021) The molecular evolution of function in the CFTR chloride channel. Journal of General Physiology 153:12.
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Michelle McMullen, Ainhoa Madariaga & Stephanie Lheureux. (2021) New approaches for targeting platinum-resistant ovarian cancer. Seminars in Cancer Biology 77, pages 167-181.
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Massimo Serra, Claudia Maria Hattinger, Michela Pasello, Chiara Casotti, Leonardo Fantoni, Chiara Riganti & Maria Cristina Manara. (2021) Impact of ABC Transporters in Osteosarcoma and Ewing’s Sarcoma: Which Are Involved in Chemoresistance and Which Are Not?. Cells 10:9, pages 2461.
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Frédérique Hilliou, Thomas Chertemps, Martine Maïbèche & Gaëlle Le Goff. (2021) Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. Insects 12:6, pages 544.
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Shulong Cao, Jingyi Tang, Yichun Huang, Gaofeng Li, Zhuoya Li, Wenqi Cai, Yuning Yuan, Junlong Liu, Xuqun Huang & Haiyuan Zhang. (2021) The Road of Solid Tumor Survival: From Drug-Induced Endoplasmic Reticulum Stress to Drug Resistance. Frontiers in Molecular Biosciences 8.
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Michela Levi, Luisa Vera Muscatello, Barbara Brunetti, Cinzia Benazzi, Federico Parenti, Francesca Gobbo, Giancarlo Avallone, Barbara Bacci, Elisa Zambon, Paola Valenti & Giuseppe Sarli. (2021) High Intrinsic Expression of P-glycoprotein and Breast Cancer Resistance Protein in Canine Mammary Carcinomas Regardless of Immunophenotype and Outcome. Animals 11:3, pages 658.
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Heinrich Sauer, Henning Kampmann, Farhad Khosravi, Fatemeh Sharifpanah & Maria Wartenberg. (2020) The nicotinamide phosphoribosyltransferase antagonist FK866 inhibits growth of prostate tumour spheroids and increases doxorubicin retention without changes in drug transporter and cancer stem cell protein expression. Clinical and Experimental Pharmacology and Physiology 48:3, pages 422-434.
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Vinaya Phatak, Yannick von Grabowiecki, Justyna Janus, Leah Officer, Caron Behan, Lydia Aschauer, Lucia Pinon, Hannah Mackay, Sara Zanivan, Jim C. Norman, Michael Kelly, John Le Quesne & Patricia A. J. Muller. (2021) Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. Cell Death & Disease 12:2.
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Anna Maria Lucianò, Elisa Perciballi, Mario Fiore, Donatella Del Bufalo & Ada Maria Tata. (2020) The Combination of the M2 Muscarinic Receptor Agonist and Chemotherapy Affects Drug Resistance in Neuroblastoma Cells. International Journal of Molecular Sciences 21:22, pages 8433.
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Michelle McMullen, Katherine Karakasis, Ainhoa Madariaga & Amit M. Oza. (2020) Overcoming Platinum and PARP-Inhibitor Resistance in Ovarian Cancer. Cancers 12:6, pages 1607.
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Jose J. G. Marin, Maria A. Serrano, Maria J. Monte, Anabel Sanchez-Martin, Alvaro G. Temprano, Oscar Briz & Marta R. Romero. (2020) Role of Genetic Variations in the Hepatic Handling of Drugs. International Journal of Molecular Sciences 21:8, pages 2884.
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Petra M. Hermann, Alexander C. Perry, Izen Hamad & Willem C. Wildering. (2020) Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment. Journal of Experimental Biology.
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Ruba Al-Abdulla, Laura Perez-Silva, Elisa Lozano, Rocio I.R. Macias, Elisa Herraez, Mar Abad, Nerea Segues, Luis Bujanda, Oscar Briz & Jose J.G. Marin. (2020) Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters. Biochemical Pharmacology 171, pages 113682.
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