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Pharmacodynamics, efficacy, safety and administration of intra-articular therapies for knee osteoarthritis

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Pages 1021-1032 | Received 18 Sep 2019, Accepted 08 Nov 2019, Published online: 13 Nov 2019

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Win Min Oo, Christopher Little, Vicky Duong & David J Hunter. (2021) The Development of Disease-Modifying Therapies for Osteoarthritis (DMOADs): The Evidence to Date. Drug Design, Development and Therapy 15, pages 2921-2945.
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Yin Zhang, Xinji Chen, Yu Tong, Junchao Luo & Qing Bi. (2020) Development and Prospect of Intra-Articular Injection in the Treatment of Osteoarthritis: A Review. Journal of Pain Research 13, pages 1941-1955.
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Alberto Migliore, Marco Paoletta, Antimo Moretti, Sara Liguori & Giovanni Iolascon. (2020) The perspectives of intra-articular therapy in the management of osteoarthritis. Expert Opinion on Drug Delivery 17:9, pages 1213-1226.
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Articles from other publishers (27)

Vijay Shetty & Clevio Desouza. (2024) Catastrophic complication after intra-articular injection of platelet-rich plasma – Case report. Journal of Orthopaedic Reports 3:1, pages 100254.
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Biao Tan, Yan Yan, Qiujun Zhou, Qiang Ran, Hong Chen, Shiyi Sun, Weizhong Lu, Weiheng Chen & Jiajun Wang. (2023) Kinesitherapy for Knee Osteoarthritis Patients Physical and Psychological Health Based on “Traditional Chinese Exercise” Management Modalities: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials. Orthopaedic Surgery.
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Md Al Amin Howlader, Ahmad Almigdad, Jannatul Ferdousy Urmi & Hassan Ibrahim. (2023) Efficacy and Safety of Hyaluronic Acid and Platelet-Rich Plasma Combination Therapy Versus Platelet-Rich Plasma Alone in Treating Knee Osteoarthritis: A Systematic Review. Cureus.
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Win Min Oo & J Hunter. (2023) Intra-articular Therapies for Knee Osteoarthritis: Current Update. Current Treatment Options in Rheumatology 9:3, pages 99-119.
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Gulnur Zhakhina, Arnur Gusmanov, Yesbolat Sakko, Sauran Yerdessov, Yuliya Semenova, Dina Saginova, Arman Batpen & Abduzhappar Gaipov. (2023) The Regional Burden and Disability-Adjusted Life Years of Knee Osteoarthritis in Kazakhstan 2014–2020. Biomedicines 11:1, pages 216.
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Shengfa Li, Peihua Cao, Tianyu Chen & Changhai Ding. (2023) Latest insights in disease-modifying osteoarthritis drugs development. Therapeutic Advances in Musculoskeletal Disease 15, pages 1759720X2311698.
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Win Min Oo & David J. Hunter. (2023) Efficacy, Safety, and Accuracy of Intra-articular Therapies for Hand Osteoarthritis: Current Evidence. Drugs & Aging 40:1, pages 1-20.
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Qing Zhang, Tuodong Liu, Yuan Gu, Yongquan Gao & Jiangdong Ni. (2022) Efficacy and safety of platelet-rich plasma combined with hyaluronic acid versus platelet-rich plasma alone for knee osteoarthritis: a systematic review and meta-analysis. Journal of Orthopaedic Surgery and Research 17:1.
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Poupak Rahimzadeh, Farnad Imani, Damon Azad Ehyaei & Seyed Hamid Reza Faiz. (2022) Efficacy of Oxygen-Ozone Therapy and Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Meta-analysis and Systematic Review. Anesthesiology and Pain Medicine 12:4.
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Ichiro Sekiya, Sho Sasaki, Yugo Miura, Hayato Aoki, Hisako Katano, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga & Nobutake Ozeki. (2022) Medial Tibial Osteophyte Width Strongly Reflects Medial Meniscus Extrusion Distance and Medial Joint Space Width Moderately Reflects Cartilage Thickness in Knee Radiographs. Journal of Magnetic Resonance Imaging 56:3, pages 824-834.
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Lixia Jin, Kangli Xu, Yun Liang, Peng Du, Shengcheng Wan & Chang Jiang. (2022) Effect of hyaluronic acid on cytokines and immune cells change in patients of knee osteoarthritis. BMC Musculoskeletal Disorders 23:1.
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Siam-Yee Lee, Pooi-Fong Wong, Juliana Jamal & Margaret M. Roebuck. (2022) Naturally-derived endoplasmic reticulum stress inhibitors for osteoarthritis?. European Journal of Pharmacology 922, pages 174903.
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Win Min Oo. (2022) Prospects of Disease-Modifying Osteoarthritis Drugs. Clinics in Geriatric Medicine 38:2, pages 397-432.
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Win Min Oo & David J. Hunter. (2022) Repurposed and investigational disease-modifying drugs in osteoarthritis (DMOADs). Therapeutic Advances in Musculoskeletal Disease 14, pages 1759720X2210902.
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Win Min Oo & David J Hunter. (2021) Nerve Growth Factor (NGF) Inhibitors and Related Agents for Chronic Musculoskeletal Pain: A Comprehensive Review. BioDrugs 35:6, pages 611-641.
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Peter Hanson, Alan Kivitz, Purvi Mehra, Louis Kwong, Amy Cinar, Joelle Lufkin & Scott D. Kelley. (2021) Safety and Systemic Exposure of Triamcinolone Acetonide Following Ultrasound-Guided Intra-Articular Injection of Triamcinolone Extended-Release or Standard Triamcinolone Acetonide in Patients with Shoulder Osteoarthritis: An Open-Label, Randomized Study. Drugs in R&D 21:3, pages 285-293.
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Di Zhao, Jian-ke Pan, Wei-yi Yang, Yan-hong Han, Ling-feng Zeng, Gui-hong Liang & Jun Liu. (2021) Intra-Articular Injections of Platelet-Rich Plasma, Adipose Mesenchymal Stem Cells, and Bone Marrow Mesenchymal Stem Cells Associated With Better Outcomes Than Hyaluronic Acid and Saline in Knee Osteoarthritis: A Systematic Review and Network Meta-analysis. Arthroscopy: The Journal of Arthroscopic & Related Surgery 37:7, pages 2298-2314.e10.
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Maria-Luisa Pérez-Lozano, Annabelle Cesaro, Marija Mazor, Eric Esteve, Sabine Berteina-Raboin, Thomas M. Best, Eric Lespessailles & Hechmi Toumi. (2021) Emerging Natural-Product-Based Treatments for the Management of Osteoarthritis. Antioxidants 10:2, pages 265.
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Win Min Oo, James M. Linklater, Kim L. Bennell, Danielle Pryke, Shirley Yu, Kai Fu, Xia Wang, Vicky Duong & David J. Hunter. (2021) Are OMERACT Knee Osteoarthritis Ultrasound Scores Associated With Pain Severity, Other Symptoms, and Radiographic and Magnetic Resonance Imaging Findings?. The Journal of Rheumatology 48:2, pages 270-278.
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Seung-Suk Seo, In-Seung Lee & Gi-Hun Lee. 2021. A Strategic Approach to Knee Arthritis Treatment. A Strategic Approach to Knee Arthritis Treatment 171 212 .
Gianfranco Gigliucci, Giovanni Iolascon, Biagio Moretti, Umberto Tarantino, Luca Gallelli, Marco Paoletta, Giovanna Picarelli & Alberto Migliore. (2020) The evidence of surgery delay after viscosupplementation is increasing. Beyond Rheumatology 2:3, pages 79-82.
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Jinlong Zhao, Hetao Huang, Guihong Liang, Ling-feng Zeng, Weiyi Yang & Jun Liu. (2020) Effects and safety of the combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) in the treatment of knee osteoarthritis: a systematic review and meta-analysis. BMC Musculoskeletal Disorders 21:1.
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Tsvetoslav Georgiev. (2020) Multimodal approach to intraarticular drug delivery in knee osteoarthritis. Rheumatology International 40:11, pages 1763-1769.
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Ruojin Li, Hongwei Chen, Jiahao Feng, Ying Xiao, Haoyang Zhang, Christopher Wai-Kei Lam & Hong Xiao. (2020) Effectiveness of Traditional Chinese Exercise for Symptoms of Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. International Journal of Environmental Research and Public Health 17:21, pages 7873.
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E. UYGUR, İ. TÜRKMEN, B. ÖZTURAN & O. POYANLI. (2020) Safety and Efficacy of Intra-Articular 20 mg/2 ml Hyaluronic Acid Injection for the Non-Operative Palliation Treatment of Osteoarthritis of the Knee Joint. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 87:4, pages 273-277.
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Ting Yu, ShiFan Yan, ZhenHai Chi, DaoCheng Zhu, Pan Cheng, HaiYan Li, SiYu Qin, GenPing Zhong, XiLin Ouyang, RiXin Chen & Lin Jiao. (2020) Comparative efficacy and safety of injection therapies for knee osteoarthritis. Medicine 99:47, pages e22943.
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Andrade Carlos Augusto Ferreira de, Isabel Ruguê Genov, Sara Regina Neto Pereira, Joao Mauricio Barreto, Max Rogério Freitas Ramos, Eduardo Costa Freitas da Silva & Liszt Palmeira de Oliveira. (2020) Viscossuplementation for the treatment of osteoarthritis of the knee. Medicine 99:37, pages e21813.
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