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Tomoya Yamada, Samuel M. Cohen & Brian G. Lake. (2021) Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Critical Reviews in Toxicology 51:5, pages 373-394.
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Takumi Sato, Ryota Shizu, Yoshie Miura, Takuomi Hosaka, Yuichiro Kanno, Takamitsu Sasaki & Kouichi Yoshinari. (2022) Development of a strategy to identify and evaluate direct and indirect activators of constitutive androstane receptor in rats. Food and Chemical Toxicology 170, pages 113510.
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Kouichi Yoshinari & Ryota Shizu. (2022) Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development. Drug Metabolism and Disposition 50:7, pages 1019-1026.
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Zhicheng Duan, Tingting Yang, Lin Li, Xue Wang, Chujing Wei, Ziyin Xia, Yuanyuan Chai, Xin Huang, Luyong Zhang & Zhenzhou Jiang. (2022) Comparison of bile acids profiles in the enterohepatic circulation system of mice and rats. The Journal of Steroid Biochemistry and Molecular Biology 220, pages 106100.
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Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang & Huichang Bi. (2022) Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update. Drug Metabolism and Disposition 50:5, pages 636-645.
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Mark E. Mazin, Andrei A. Yarushkin, Yuliya A. Pustylnyak, Elena A. Prokopyeva & Vladimir O. Pustylnyak. (2022) Promotion of NR1I3-mediated liver growth is accompanied by STAT3 activation. Molecular Biology Reports 49:5, pages 4089-4093.
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Michela Cantiello, Monica Carletti, Mery Giantin, Giulia Gardini, Francesca Capolongo, Paolo Cascio, Marianna Pauletto, Flavia Girolami, Mauro Dacasto & Carlo Nebbia. (2022) Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization. International Journal of Molecular Sciences 23:7, pages 3564.
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Ryota Shizu, Mai Ishimura, Sumihito Nobusawa, Takuomi Hosaka, Takamitsu Sasaki, Satoru Kakizaki & Kouichi Yoshinari. (2021) The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice. Archives of Toxicology 95:3, pages 1089-1102.
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Albert Braeuning & Petr Pavek. (2020) β-catenin signaling, the constitutive androstane receptor and their mutual interactions. Archives of Toxicology 94:12, pages 3983-3991.
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Ryota Shizu, Yuta Otsuka, Kanako Ezaki, Chizuru Ishii, Shingo Arakawa, Yuto Amaike, Taiki Abe, Takuomi Hosaka, Takamitsu Sasaki, Yuichiro Kanno, Masaaki Miyata, Yasushi Yamazoe & Kouichi Yoshinari. (2020)
Antiepileptic Drug–Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator–Activated Receptor
α
and Peroxisome Proliferator–Activated Receptor
γ
Coactivator 1
α
–Dependent Gene Expression to Increase Blood Triglyceride Levels
. Molecular Pharmacology 98:5, pages 634-647.
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Maya Okamura, Ryota Shizu, Taiki Abe, Susumu Kodama, Takuomi Hosaka, Takamitsu Sasaki & Kouichi Yoshinari. (2020) PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice. Cells 9:10, pages 2296.
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Tomoya Yamada, Ayako Ohara, Naoya Ozawa, Keiko Maeda, Miwa Kondo, Yu Okuda, Jun Abe, Samuel M Cohen & Brian G Lake. (2020) Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice. Toxicological Sciences 177:2, pages 362-376.
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Yuliya A. Pustylnyak, Lyudmila F. Gulyaeva & Vladimir O. Pustylnyak. (2020) Noncanonical Constitutive Androstane Receptor Signaling in Gene Regulation. International Journal of Molecular Sciences 21:18, pages 6735.
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Philip Marx-Stoelting, Constanze Knebel & Albert Braeuning. (2020) The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity. Cells 9:5, pages 1192.
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