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Expert Opinion on Drug Metabolism & Toxicology Volume 17, 2021 - Issue 11
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Review

Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review

Edmond Atallaha School of Medicine, Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK;b National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals Nhs Trust and the University of Nottingham, Nottingham, UKORCID Iconhttps://orcid.org/0000-0002-7341-9174View further author information
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Cristiana Freixoc Cintesis, Center for Health Technology and Services Research, Faculdade De Medicina Da Universidade Do Porto, Porto, PortugalView further author information
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Ismael Alvarez-Alvarezd Servicio De Farmacología Clínica and Ugc Aparato Digestivo, Hospital Universitario Virgen De La Victoria, Instituto De Investigación Biomédica De Málaga-IBIMA, Universidad De Málaga, Málaga, Spain;e Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd), Madrid, SpainORCID Iconhttps://orcid.org/0000-0001-6271-0604View further author information
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F.J Cuberoe Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd), Madrid, Spain;f Department of Immunology, Ophthalmology, and ENT, Complutense University School of Medicine, Madrid, SpainORCID Iconhttps://orcid.org/0000-0003-1499-650XView further author information
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Alexander L. Gerbesg Department of Medicine, Liver Centre Munich, University Hospital Munich, Munich, GermanyView further author information
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Gerd A. Kullak-Ublickh Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zurich, Switzerland;i Mechanistic Safety, CMO & Patient Safety, Global Drug Development, Novartis Pharma, Basel, SwitzerlandORCID Iconhttps://orcid.org/0000-0002-0757-4408View further author information
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Guruprasad P. Aithala School of Medicine, Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK;b National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals Nhs Trust and the University of Nottingham, Nottingham, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3924-4830View further author information
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Pages 1327-1343 | Received 20 Jul 2021, Accepted 21 Oct 2021, Published online: 15 Nov 2021

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MN Liu, M. Au, M. Bishara, T. Worland, D. Con, S. Chew, A. McNiece, H. Gronbaek, P. Sluka & AJ Nicoll. (2023) Serum interleukin-4 is elevated in clinical drug-induced liver injury. Scandinavian Journal of Gastroenterology 58:12, pages 1499-1504.
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Articles from other publishers (4)

Ji Eon Park, Chi-Hoon AhnHyo-Jung LeeDeok Yong SimSu Yeon ParkBonglee KimBum Sang ShimDae Young Lee & Sung-Hoon Kim. (2023) Antioxidant-Based Preventive Effect of Phytochemicals on Anticancer Drug-Induced Hepatotoxicity. Antioxidants & Redox Signaling.
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Kodihalli C. Ravindra, Vishal S. Vaidya, Zhenyu Wang, Joel D. Federspiel, Richard Virgen-Slane, Robert A. Everley, Jane I. Grove, Camilla Stephens, Mireia F. Ocana, Mercedes Robles-Díaz, M. Isabel Lucena, Raul J. Andrade, Edmond Atallah, Alexander L. Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J. Fowell, Hyder Hussaini, Einar S. Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M. Elsharkawy, William J. H. Griffiths, Craig Hyde, James W. Dear, Guruprasad P. Aithal & Shashi K. Ramaiah. (2023) Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans. Nature Communications 14:1.
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BJ Olsen. (2022) A masterclass in gastroenterology practice. Gastrointestinal Nursing 20:6, pages 18-20.
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Sabine Weber & Alexander L. Gerbes. (2022) Challenges and Future of Drug-Induced Liver Injury Research—Laboratory Tests. International Journal of Molecular Sciences 23:11, pages 6049.
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