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Expert Opinion on Drug Metabolism & Toxicology Volume 18, 2022 - Issue 2
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Review

An Update on the Use of Allometric and Other Scaling Methods to Scale Drug Clearance in Children: Towards Decision Tables

Anne van Rongena Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The NetherlandsView further author information
,
Elke HJ Krekelsa Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The NetherlandsView further author information
,
Elisa AM Calvierb Sanofi Pharmacokinetics-Dynamics and Metabolism (PKDM), Translational Medicine and Early Development, Sanofi R&d, Montpellier, FranceView further author information
,
Saskia N de Wildtc Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands;d Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The NetherlandsView further author information
,
An Vermeulene Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium;f Janssen R&D, a Division of Janssen Pharmaceutica Nv, Beerse, BelgiumView further author information
&
Catherijne AJ Knibbea Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands;g Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The NetherlandsCorrespondence[email protected]
View further author information
Pages 99-113 | Received 06 Oct 2021, Accepted 07 Jan 2022, Published online: 25 Feb 2022

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Tan Zhang, Elke H.J. Krekels, Cornelis Smit & Catherijne A.J. Knibbe. (2022) Drug pharmacokinetics in the obese population: challenging common assumptions on predictors of obesity-related parameter changes. Expert Opinion on Drug Metabolism & Toxicology 18:10, pages 657-674.
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Karel Allegaert, Mohammad Yaseen Abbasi, Pieter Annaert & Olusola Olafuyi. (2022) Current and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates. Expert Opinion on Drug Metabolism & Toxicology 18:5, pages 301-312.
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Articles from other publishers (2)

Abdelbaset Elzagallaai, Charlotte Barker, Tamorah Lewis, Ronald Cohn & Michael Rieder. (2023) Advancing Precision Medicine in Paediatrics: Past, present and future. Cambridge Prisms: Precision Medicine 1.
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Hirsh Elhence, Kanokporn Mongkolrattanothai, Sindhu Mohandas & Michael N. Neely. (2022) Isavuconazole Pharmacokinetics and Pharmacodynamics in Children. Pharmaceutics 15:1, pages 75.
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