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Nanotoxicology Volume 15, 2021 - Issue 6
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Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death

Longbin Zhanga Institute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Liyong Zoua Institute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Xuejun Jiangb Center of Experimental Teaching for Public Health, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Shuqun Chengc Department of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Jun Zhanga Institute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Xia Qind Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaView further author information
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Zhexue Qine Institute of Cardiovascular Diseases of PLA, the Second Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing, People’s Republic of ChinaView further author information
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Chengzhi Chenc Department of Occupational and Environmental Health, School of Public Health and Management, Chongqing Medical University, Chongqing, People’s Republic of China;f Dongsheng Lung-Brain Disease Joint Lab, Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1087-4911View further author information
ORCID Icon &
Zhen Zoua Institute of Life Sciences, Chongqing Medical University, Chongqing, People’s Republic of China;f Dongsheng Lung-Brain Disease Joint Lab, Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1651-591XView further author information
ORCID Icon show all
Pages 779-797 | Received 10 Jan 2021, Accepted 15 Apr 2021, Published online: 10 May 2021

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Cantao Yang, Zhaohong Lu, Yinyin Xia, Jun Zhang, Zhen Zou, Chengzhi Chen, Xiaoliang Wang, Xin Tian, Shuqun Cheng & Xuejun Jiang. (2023) Alterations of Gut-Derived Melatonin in Neurobehavioral Impairments Caused by Zinc Oxide Nanoparticles. International Journal of Nanomedicine 18, pages 1899-1914.
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Articles from other publishers (8)

Ziqi Jiang, Yu Jiang, Jingchuan Fan, Jun Zhang, Ge Xu, Yinzhen Fan, Liyu Zhang, Xia Qin, Xuejun Jiang, Lejiao Mao, Gang Liu, Chengzhi Chen & Zhen Zou. (2023) Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles. Toxicology Letters 373, pages 62-75.
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Niloufar A. Boghdeh, Kenneth H. Risner, Michael D. Barrera, Clayton M. Britt, David K. Schaffer, Farhang Alem, Jacquelyn A. Brown, John P. Wikswo & Aarthi Narayanan. (2022) Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus. Viruses 14:12, pages 2799.
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Na Li, Hang Du, Lejiao Mao, Ge Xu, Mengling Zhang, Yinzhen Fan, Xiaomei Dong, Lijun Zheng, Bin Wang, Xia Qin, Xuejun Jiang, Chengzhi Chen, Zhen Zou & Jun Zhang. (2022) Reciprocal regulation of NRF2 by autophagy and ubiquitin–proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles. Journal of Nanobiotechnology 20:1.
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Yandan ZhangLingbing ZhangLejiao MaoJingchuan FanXuejun Jiang, Na LiYinzhen FanZiqi JiangXia QinFeng QiuYu Jiang, Gang Liu, Jun Zhang, Chengzhi Chen & Zhen Zou. (2022) Intestinal Microbiota-derived Propionic Acid Protects against Zinc Oxide Nanoparticle–induced Lung Injury. American Journal of Respiratory Cell and Molecular Biology 67:6, pages 680-694.
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Hejun Zhang, Yalong Gao, Tuo Li, Fanjian Li, Ruilong Peng, Cong Wang, Shu Zhang & Jianning Zhang. (2022) Recombinant Human Annexin A5 Alleviated Traumatic-Brain-Injury Induced Intestinal Injury by Regulating the Nrf2/HO-1/HMGB1 Pathway. Molecules 27:18, pages 5755.
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Sebastin Martin, Laura de Haan, Ignacio Miro Estruch, Kai Moritz Eder, Anne Marzi, Jürgen Schnekenburger, Magda Blosi, Anna Costa, Giulia Antonello, Enrico Bergamaschi, Chiara Riganti, David Beal, Marie Carrière, Olivier Taché, Gary Hutchison, Eva Malone, Lesley Young, Luisa Campagnolo, Fabio La Civita, Antonio Pietroiusti, Stéphanie Devineau, Armelle Baeza, Sonja Boland, Cai Zong, Gaku Ichihara, Bengt Fadeel & Hans Bouwmeester. (2022) Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials. Frontiers in Toxicology 4.
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Ning Li, Yali Zhao, Fangyu Wang, Lianjun Song, Mingwu Qiao, Tianlin Wang & Xianqing Huang. (2022) Folic acid alleviates lead acetate-mediated cardiotoxicity by down-regulating the expression levels of Nrf2, HO-1, GRP78, and CHOP proteins. Environmental Science and Pollution Research 29:37, pages 55916-55927.
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Peizheng Xiong, Xiangming Huang, Naijing Ye, Qunwen Lu, Gang Zhang, Shunlin Peng, Hongbo Wang & Yiyao Liu. (2022) Cytotoxicity of Metal‐Based Nanoparticles: From Mechanisms and Methods of Evaluation to Pathological Manifestations. Advanced Science 9:16.
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