Advanced search
Publication Cover
Expert Review of Clinical Immunology Volume 12, 2016 - Issue 12
Submit an article Journal homepage
740
Views
59
CrossRef citations to date
0
Altmetric
Review

Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity

Andrea ChiricozziDepartment of Dermatology, University of Pisa, Pisa, Italy
,
Annunziata RaimondoDepartment of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy
,
Serena LemboDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy
,
Francesca FaustiSkin Biology Laboratory, University of Rome Tor Vergata, Rome, Italy
,
Valentina DiniDepartment of Dermatology, University of Pisa, Pisa, Italy
,
Antonio CostanzoDermatology Unit, Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Rome, Italy
,
Giuseppe MonfrecolaDepartment of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy
,
Nicola BalatoDepartment of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy
,
Fabio AyalaDepartment of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy
,
Marco RomanelliDepartment of Dermatology, University of Pisa, Pisa, Italy
&
Anna BalatoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, ItalyCorrespondence[email protected]
 show all
Pages 1299-1308 | Received 25 Mar 2016, Accepted 10 Jun 2016, Published online: 27 Jun 2016

Citations (59)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (10)

Roaa Aljohani. (2022) Metabolic Syndrome and Its Components in Psoriatic Arthritis. Open Access Rheumatology: Research and Reviews 14, pages 7-16.
Read now
M Galluzzo, G Caldarola, C De Simone, N Bernardini, G Moretta, S Pallotta, E Botti, E Campione, F Pirro, C. Potenza, L Bianchi & K Peris. (2021) Use of brodalumab for the treatment of chronic plaque psoriasis: a one-year real-life study in the Lazio region, Italy. Expert Opinion on Biological Therapy 21:9, pages 1299-1310.
Read now
Francesco Caso, Maria Sole Chimenti, Luca Navarini, Piero Ruscitti, Rosario Peluso, Nicolò Girolimetto, Antonio Del Puente, Roberto Giacomelli, Raffaele Scarpa & Luisa Costa. (2020) Metabolic Syndrome and psoriatic arthritis: considerations for the clinician. Expert Review of Clinical Immunology 16:4, pages 409-420.
Read now
Maria Dalamaga & Evangelia Papadavid. (2019) Can we better strategize our choice of pharmacotherapy for patients with co-morbid psoriasis and obesity?. Expert Opinion on Pharmacotherapy 20:11, pages 1303-1308.
Read now
Andrea Chiricozzi, Paolo Gisondi & Giampiero Girolomoni. (2019) The pharmacological management of patients with comorbid psoriasis and obesity. Expert Opinion on Pharmacotherapy 20:7, pages 863-872.
Read now
Tomasz Szkudelski, Iwona Hertig & Katarzyna Szkudelska. (2018) Lack of effects of myo-inositol on metabolism of primary rat adipocytes. Archives of Physiology and Biochemistry 124:4, pages 344-350.
Read now
Annunziata Raimondo, Anna Balato, Matteo Megna & Nicola Balato. (2018) Limitations of current monoclonal antibodies for plaque-type psoriasis and an outlook for the future. Expert Opinion on Biological Therapy 18:6, pages 605-607.
Read now
Jillian Frieder, Dario Kivelevitch, Connie Tran Fiore, Saadeddine Saad & Alan Menter. (2018) The impact of biologic agents on health-related quality of life outcomes in patients with psoriasis. Expert Review of Clinical Immunology 14:1, pages 1-19.
Read now
Anna Balato, Emanuele Scala, Nicola Balato, Giuseppina Caiazzo, Roberta Di Caprio, Giuseppe Monfrecola, Annunziata Raimondo, Serena Lembo & Fabio Ayala. (2017) Biologics that inhibit the Th17 pathway and related cytokines to treat inflammatory disorders. Expert Opinion on Biological Therapy 17:11, pages 1363-1374.
Read now
Anna Baran, Hanna Myśliwiec, Paulina Kiluk, Magdalena Świderska & Iwona Flisiak. (2017) Serum irisin levels in patients with psoriasis. Journal of Dermatological Treatment 28:4, pages 304-308.
Read now

Articles from other publishers (49)

Yifan Zhou, Tianyu Cao, Zhiguo Li, Hongjiang Qiao, Erle Dang, Shuai Shao & Gang Wang. (2024) Fibroblasts in immune-mediated inflammatory diseases: The soil of inflammation. Clinical Immunology 258, pages 109849.
Crossref
Andy W C Man, Yawen Zhou, Gisela Reifenberg, Alica Camp, Thomas Münzel, Andreas Daiber, Ning Xia & Huige Li. (2023) Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin. Cardiovascular Research.
Crossref
Noha M. Dawoud, Marwa M. Dawoud, Sally M. El Hefnawy, Hayam A. Abdellatif, Naglaa H. Abdellatif, Sara S. Gaafar & Iman Seleit. (2023) Circulating and/or cutaneous irisin resistance: A novel link among androgenetic alopecia, comorbid metabolic syndrome and cardiovascular risks. Journal of Cosmetic Dermatology 22:9, pages 2584-2597.
Crossref
Carolina Constantin, Mihaela Surcel, Adriana Munteanu & Monica Neagu. (2023) Insights into Nutritional Strategies in Psoriasis. Nutrients 15:16, pages 3528.
Crossref
Mateusz Matwiejuk, Hanna Mysliwiec, Bartłomiej Lukaszuk, Marta Lewoc, Hend Malla, Piotr Mysliwiec, Jacek Dadan, Adrian Chabowski & Iwona Flisiak. (2023) The Interplay between Bioactive Sphingolipids in the Psoriatic Skin and the Severity of the Disease. International Journal of Molecular Sciences 24:14, pages 11336.
Crossref
Janani A. Palanivel & George W. M. Millington. (2023) Obesity‐induced immunological effects on the skin. Skin Health and Disease 3:3.
Crossref
Shu-min Kong, Xiao-yan Sun, Wen-ya Cui & Yu-chun Cao. (2023) Chemerin Exacerbates Psoriasis by Stimulating Keratinocyte Proliferation and Cytokine Production. Current Medical Science 43:2, pages 399-408.
Crossref
Jie-Fang Gao, Liu Tang, Fei Luo, Lu Chen, Yi-Yuan Zhang & Hong Ding. (2023) Myricetin treatment has ameliorative effects in DNFB-induced atopic dermatitis mice under high-fat conditions. Toxicological Sciences 191:2, pages 308-320.
Crossref
Alejandra Villarreal‐Martinez, Laura Elia Martinez‐de‐Villarreal, Minerva Gomez‐Flores, Sonia Chavez‐Alvarez, Ricardo Cerda‐Flores, Jorge Ocampo‐Candiani, Consuelo Ruiz‐Herrera, Marcelo R. Rodriguez‐Rivera, Jesús Zacarías Villarreal‐Perez, José Gerardo Gonzalez‐Gonzalez & Geovana Calvo‐Anguiano. (2022) Mitochondrial dysfunction: The pathological link between psoriasis and insulin resistance?. Journal of the European Academy of Dermatology and Venereology 37:2, pages 340-347.
Crossref
Stefano Piaserico, Gloria Orlando & Francesco Messina. (2022) Psoriasis and Cardiometabolic Diseases: Shared Genetic and Molecular Pathways. International Journal of Molecular Sciences 23:16, pages 9063.
Crossref
Zuzanna Piętowska, Danuta Nowicka & Jacek Szepietowski. (2022) Can Biological Drugs Diminish the Risk of Sarcopenia in Psoriatic Patients? A Systematic Review. Life 12:3, pages 435.
Crossref
Zhuolin Guo, Yichun Yang, Yanhang Liao, Yulin Shi & Ling-juan Zhang. (2022) Emerging Roles of Adipose Tissue in the Pathogenesis of Psoriasis and Atopic Dermatitis in Obesity. JID Innovations 2:1, pages 100064.
Crossref
Xiaomei Chen, Hongmei Xiang, Lingling Tan, Jie Zhou, Jing Tang, Xiaoyi Hu & Ming Yang. (2021) Psoriasis Is Associated With Myosteatosis but Not Sarcopenia: A Case-Control Study. Frontiers in Medicine 8.
Crossref
Jung Eun Kim, Hye Ran Kim, Jin Cheol Kim, Eun Soo Lee, Choon Hee Chung, Eun Young Lee & Bo Young Chung. (2021) Tetrahydrocurcumin Ameliorates Skin Inflammation by Modulating Autophagy in High-Fat Diet-Induced Obese Mice. BioMed Research International 2021, pages 1-8.
Crossref
Dorota Kozłowska, Hanna Myśliwiec, Ewa Harasim-Symbor, Anna Justyna Milewska, Adrian Chabowski & Iwona Flisiak. (2021) Serum fatty acid binding protein 5 (FABP5) as a potential biomarker of inflammation in psoriasis. Molecular Biology Reports 48:5, pages 4421-4429.
Crossref
Hideki Nakajima, Kimiko Nakajima, Mikiro Takaishi, Kentaro Ohko, Satoshi Serada, Minoru Fujimoto, Tetsuji Naka & Shigetoshi Sano. (2021) The Skin–Liver Axis Modulates the Psoriasiform Phenotype and Involves Leucine-Rich α-2 Glycoprotein. The Journal of Immunology 206:7, pages 1469-1477.
Crossref
Sabrina Porta, Matilde Otero-Losada, Rodolfo A. Kölliker Frers, Vanesa Cosentino, Eduardo Kerzberg & Francisco Capani. (2021) Adipokines, Cardiovascular Risk, and Therapeutic Management in Obesity and Psoriatic Arthritis. Frontiers in Immunology 11.
Crossref
Anna BALATO, Giuseppina CAIAZZO, Nicola BALATO & Maddalena NAPOLITANO. (2021) Psoriatic arthritis onset in psoriatic patients receiving UV phototherapy in Italy. Giornale Italiano di Dermatologia e Venereologia 155:6.
Crossref
Pelagia Katsimbri, Emmanouil Korakas, Aikaterini Kountouri, Ignatios Ikonomidis, Elias Tsougos, Dionysios Vlachos, Evangelia Papadavid, Athanasios Raptis & Vaia Lambadiari. (2021) The Effect of Antioxidant and Anti-Inflammatory Capacity of Diet on Psoriasis and Psoriatic Arthritis Phenotype: Nutrition as Therapeutic Tool?. Antioxidants 10:2, pages 157.
Crossref
Kyriaki Paroutoglou, Evangelia Papadavid, Gerasimos Socrates Christodoulatos & Maria Dalamaga. (2020) Deciphering the Association Between Psoriasis and Obesity: Current Evidence and Treatment Considerations. Current Obesity Reports 9:3, pages 165-178.
Crossref
Andrea Chiricozzi, Giulia Giovanardi, Dante R. Caposiena Caro, Michela Iannone, Clara De Simone, Maria V. Cannizzaro, Teresa Oranges, Barbara Fossati, Eleonora Di Matteo, Valentina Dini, Luca Bianchi & Ketty Peris. (2020) Characterization of comorbid conditions burdening hidradenitis suppurativa: a multicentric observational study. Giornale Italiano di Dermatologia e Venereologia 155:3.
Crossref
Jingyi Yang & Yan Gao. (2020) Clinical relevance of serum omentin‐1 levels as a biomarker of prognosis in patients with acute cerebral infarction. Brain and Behavior 10:7.
Crossref
Anna Michalak-Stoma, Joanna Bartosińska, Małgorzata Kowal, Dorota Raczkiewicz, Dorota Krasowska & Grażyna Chodorowska. (2020) IL-17A in the Psoriatic Patients’ Serum and Plaque Scales as Potential Marker of the Diseases Severity and Obesity. Mediators of Inflammation 2020, pages 1-9.
Crossref
Gianluca Iacobellis & Alexandra C. Villasante Fricke. 2020. Epicardial Adipose Tissue. Epicardial Adipose Tissue 155 165 .
Yi Kong, Suhan Zhang, Ruifang Wu, Xin Su, Daoquan Peng, Ming Zhao & Yuwen Su. (2019) New insights into different adipokines in linking the pathophysiology of obesity and psoriasis. Lipids in Health and Disease 18:1.
Crossref
Alexandra C. Villasante Fricke & Gianluca Iacobellis. (2019) Epicardial Adipose Tissue: Clinical Biomarker of Cardio-Metabolic Risk. International Journal of Molecular Sciences 20:23, pages 5989.
Crossref
Masafumi Aoki & Takatoshi Murase. (2019) Obesity-associated insulin resistance adversely affects skin function. PLOS ONE 14:10, pages e0223528.
Crossref
Francesco Caso, Loredana Postiglione, Bianca Covelli, Margherita Ricciardone, Gaetano Di Spigna, Pietro Formisano, Vittoria D’Esposito, Nicolò Girolimetto, Marco Tasso, Rosario Peluso, Luca Navarini, Massimo Ciccozzi, Domenico Paolo Emanuele Margiotta, Francesca Oliviero, Antonella Afeltra, Leonardo Punzi, Antonio Del Puente, Raffaele Scarpa & Luisa Costa. (2019) Pro-inflammatory adipokine profile in psoriatic arthritis: results from a cross-sectional study comparing PsA subset with evident cutaneous involvement and subset “sine psoriasis”. Clinical Rheumatology 38:9, pages 2547-2552.
Crossref
Shelley Gorman, Barbora de Courten & Robyn Lucas. (2019) Systematic Review of the Effects of Ultraviolet Radiation on Markers of Metabolic Dysfunction. Clinical Biochemist Reviews 40:3, pages 147-162.
Crossref
Carmen Rodríguez-Cerdeira, Mónica Cordeiro-Rodríguez, Miguel Carnero-Gregorio, Adriana López-Barcenas, Erick Martínez-Herrera, Gabriella Fabbrocini, Ardiana Sinani, Roberto Arenas-Guzmán & José Luís González-Cespón. (2019) Biomarkers of Inflammation in Obesity-Psoriatic Patients. Mediators of Inflammation 2019, pages 1-14.
Crossref
Alvaro Gonzalez-Cantero, Jorge Gonzalez-Cantero, Ana Isabel Sanchez-Moya, Cristina Perez-Hortet, Salvador Arias-Santiago, Cristina Schoendorff-Ortega & Jorge Luis Gonzalez-Calvin. (2019) Subclinical atherosclerosis in psoriasis. Usefulness of femoral artery ultrasound for the diagnosis, and analysis of its relationship with insulin resistance. PLOS ONE 14:2, pages e0211808.
Crossref
Costas A Constantinou, George E Fragoulis & Elena Nikiphorou. (2019) Hidradenitis suppurativa: infection, autoimmunity, or both?. Therapeutic Advances in Musculoskeletal Disease 11, pages 1759720X1989548.
Crossref
Sunaina Rengarajan & Milan J. Anadkat. (2019) SnapshotDx Quiz: January 2019. Journal of Investigative Dermatology 139:1, pages e1-e4.
Crossref
Silje M. Solberg, Lene F. Sandvik, Marianne Eidsheim, Roland Jonsson, Yenan T. Bryceson & Silke Appel. (2018) Serum cytokine measurements and biological therapy of psoriasis - Prospects for personalized treatment?. Scandinavian Journal of Immunology 88:6, pages e12725.
Crossref
Patricia Moreira GomesRodrigo de Oliveira. (2018) Obesidade e diabetes mellitus no paciente reumatológico. Revista Paulista de Reumatologia:2018 jul-set;17(3), pages 10-14.
Crossref
Diana Herbert, Sandra Franz, Yulia Popkova, Ulf Anderegg, Jürgen Schiller, Katharina Schwede, Axel Lorz, Jan C. Simon & Anja Saalbach. (2018) High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players. Journal of Investigative Dermatology 138:9, pages 1999-2009.
Crossref
Giuseppina Caiazzo, Gabriella Fabbrocini, Roberta Di Caprio, Annunziata Raimondo, Emanuele Scala, Nicola Balato & Anna Balato. (2018) Psoriasis, Cardiovascular Events, and Biologics: Lights and Shadows. Frontiers in Immunology 9.
Crossref
Gisela Helfer & Qing-Feng Wu. (2018) Chemerin: a multifaceted adipokine involved in metabolic disorders. Journal of Endocrinology 238:2, pages R79-R94.
Crossref
A. Balato & A. Raimondo. (2018) Novel interactions among ultraviolet B, skin and adipose tissue. British Journal of Dermatology 178:2, pages 327-328.
Crossref
E.J. Kim, Y.K. Kim, S. Kim, J.E. Kim, Y.D. Tian, E.J. Doh, D.H. Lee & J.H. Chung. (2018) Adipochemokines induced by ultraviolet irradiation contribute to impaired fat metabolism in subcutaneous fat cells. British Journal of Dermatology 178:2, pages 492-501.
Crossref
A. Capo, G. Affaitati, M.A. Giamberardino & P. Amerio. (2017) Psoriasis and migraine. Journal of the European Academy of Dermatology and Venereology 32:1, pages 57-61.
Crossref
Ingrid Snekvik, Catherine H. Smith, Tom I.L. Nilsen, Sinéad M. Langan, Ellen H. Modalsli, Pål R. Romundstad & Marit Saunes. (2017) Obesity, Waist Circumference, Weight Change, and Risk of Incident Psoriasis: Prospective Data from the HUNT Study. Journal of Investigative Dermatology 137:12, pages 2484-2490.
Crossref
R. Sabat, A. Tsaousi, J. Rossbacher, H. Kurzen, T. Fadai, U. Schwichtenberg, S. Schneider-Burrus, G. Kokolakis & K. Wolk. (2017) Acne inversa/Hidradenitis suppurativa: Ein UpdateAcne inversa/hidradenitis suppurativa: An update. Der Hautarzt 68:12, pages 999-1006.
Crossref
Stephen Hu & Cheng-Che E. Lan. (2017) Psoriasis and Cardiovascular Comorbidities: Focusing on Severe Vascular Events, Cardiovascular Risk Factors and Implications for Treatment. International Journal of Molecular Sciences 18:10, pages 2211.
Crossref
Annunziata DattolaSimone AltobelliSalvatore MarsicoDomenico PlastinaSteven P. NisticoArmando CavalloRoberto FlorisLuca BianchiManlio Guazzaroni. (2017) Hypodermal Adipose Tissue Sonoelastography for Monitoring Treatment Response in Patients with Plaque Psoriasis. Photomedicine and Laser Surgery 35:9, pages 484-491.
Crossref
Hanna Myśliwiec, Anna Baran, Ewa Harasim-Symbor, Piotr Myśliwiec, Anna Justyna Milewska, Adrian Chabowski & Iwona Flisiak. (2017) Serum fatty acid profile in psoriasis and its comorbidity. Archives of Dermatological Research 309:5, pages 371-380.
Crossref
Olga K. Afanasiev, Cathryn Z. Zhang & Steven M. Ruhoy. (2017) TNF-inhibitor associated psoriatic alopecia: Diagnostic utility of sebaceous lobule atrophy. Journal of Cutaneous Pathology 44:6, pages 563-569.
Crossref
Hanna Myśliwiec, Anna Baran, Ewa Harasim-Symbor, Barbara Choromańska, Piotr Myśliwiec, Anna Justyna Milewska, Adrian Chabowski & Iwona Flisiak. (2016) Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. Archives of Dermatological Research 309:2, pages 79-86.
Crossref
Simona Vachatova, Ctirad Andrys, Jan Krejsek, Miloslav Salavec, Karel Ettler, Vit Rehacek, Eva Cermakova, Andrea Malkova, Zdenek Fiala & Lenka Borska. (2016) Metabolic Syndrome and Selective Inflammatory Markers in Psoriatic Patients. Journal of Immunology Research 2016, pages 1-8.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.