897
Views
25
CrossRef citations to date
0
Altmetric
Review

Biologics targeting IL-5, IL-4 or IL-13 for the treatment of asthma – an update

Pages 143-149 | Received 24 May 2016, Accepted 20 Jul 2016, Published online: 02 Aug 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Frauke Pedersen, Frederik Trinkmann, Mustafa Abdo, Anne-Marie Kirsten, Klaus F Rabe, Henrik Watz, Simonetta Baraldo, Marina Saetta, Jens M Hohlfeld & Olaf Holz. (2021) Influence of Cell Quality on Inflammatory Biomarkers in COPD Sputum Supernatant. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 487-493.
Read now
Dave Singh, Arjun Ravi & Thomas Southworth. (2017) CRTH2 antagonists in asthma: current perspectives. Clinical Pharmacology: Advances and Applications 9, pages 165-173.
Read now

Articles from other publishers (23)

Joonki Kim, Sang Heon Lee, Siqi Zhang, Sim-Kyu Bong, Aaron Taehwan Kim, Hara Lee, Xiaoyong Liu, Sang Moo Kim & Su-Nam Kim. (2023) Anti-Allergic Inflammatory Effect of Agarum cribrosum and Its Phlorotannin Component, Trifuhalol A, against the Ovalbumin-Induced Allergic Asthma Model. Current Issues in Molecular Biology 45:11, pages 8882-8893.
Crossref
Liyuan Zhang, Han Xinpeng, Seshadri Vidya Devanathadesikan, Ibrahim Ibrahim Abdel Aziz & Ling Ou. (2022) Tilianin alleviates airway inflammation in ovalbumin-induced allergic asthma in mice through the regulation of Th2 cytokines and TGF-β1/Smad markers. Arabian Journal of Chemistry 15:8, pages 103961.
Crossref
Roland Buhl, Elisabeth Bel, Arnaud Bourdin, Ignacio Dávila, Jo A. Douglass, J. Mark FitzGerald, David J. Jackson, Njira L. Lugogo, Andrea Matucci, Ian D. Pavord, Michael E. Wechsler & Monica Kraft. (2022) Effective Management of Severe Asthma with Biologic Medications in Adult Patients: A Literature Review and International Expert Opinion. The Journal of Allergy and Clinical Immunology: In Practice 10:2, pages 422-432.
Crossref
Dave Singh. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine 741 753 .
Donald T. Gracias, Gurupreet S. Sethi, Amit K. Mehta, Haruka Miki, Rinkesh K. Gupta, Hideo Yagita & Michael Croft. (2021) Combination blockade of OX40L and CD30L inhibits allergen-driven memory TH2 cell reactivity and lung inflammation. Journal of Allergy and Clinical Immunology 147:6, pages 2316-2329.
Crossref
Xiaobo Xuan, Ziyan Sun, Chenhuan Yu, Jian Chen, Mei Chen, Qili Wang & Lan Li. (2020) Network pharmacology-based study of the protective mechanism of conciliatory anti-allergic decoction on asthma. Allergologia et Immunopathologia 48:5, pages 441-449.
Crossref
Chengqiang Wang, Jia Tang, Bo Qian, Zhen Zeng, Yang Gao & Jia‐Le Song. (2020) Rubusoside alleviates the ovalbumin‐induced mice allergic asthma by modulating the NF‐κB activation. Journal of Food Biochemistry 44:5.
Crossref
Oscar Okwudiri Onyema, Yizhan Guo, Atsushi Hata, Daniel Kreisel, Andrew E. Gelman, Elizabeth A. Jacobsen & Alexander Sasha Krupnick. (2020) Deciphering the role of eosinophils in solid organ transplantation. American Journal of Transplantation 20:4, pages 924-930.
Crossref
Dóra Paróczai, Tímea Mosolygó, Dávid Kókai, Valéria Endrész, Dezső P. Virok, Attila Somfay & Katalin Burián. (2020) Chlamydia pneumoniae Influence on Cytokine Production in Steroid-Resistant and Steroid-Sensitive Asthmatics. Pathogens 9:2, pages 112.
Crossref
Koichi Ando, Akihiko Tanaka & Hironori Sagara. (2020) Comparative Efficacy and Safety of Dupilumab and Benralizumab in Patients with Inadequately Controlled Asthma: A Systematic Review. International Journal of Molecular Sciences 21:3, pages 889.
Crossref
Liqun Shang, Li Wang, Xiaolan Shi, Ning Wang, Long Zhao, Jing Wang & Cuicui Liu. (2020) HMGB1 was negatively regulated by HSF1 and mediated the TLR4/MyD88/NF-κB signal pathway in asthma. Life Sciences 241, pages 117120.
Crossref
Andrée-Anne Hudon Thibeault & Catherine Laprise. (2019) Cell-Specific DNA Methylation Signatures in Asthma. Genes 10:11, pages 932.
Crossref
Ying Feng, Cunjing Zheng, Zongpu Zhou, Huihui Xiong, Feng Feng, Fukang Xie & Zhong-dao Wu. (2019) IL-17A neutralizing antibody attenuates eosinophilic meningitis caused by Angiostrongylus cantonensis by involving IL-17RA/Traf6/NF-κB signaling. Experimental Cell Research 384:1, pages 111554.
Crossref
Shaohong Jiang, Qiang Wang, Yuxin Wang, Xicheng Song & Yu Zhang. (2019) Blockade of CCL2/CCR2 signaling pathway prevents inflammatory monocyte recruitment and attenuates OVA-Induced allergic asthma in mice. Immunology Letters 214, pages 30-36.
Crossref
Jia‐Le Song, Bo Qian, Cailing Pan, Fangfang Lv, Haipeng Wang, Yang Gao & Yanyuan Zhou. (2019) Protective activity of mogroside V against ovalbumin‐induced experimental allergic asthma in Kunming mice. Journal of Food Biochemistry 43:9.
Crossref
Pierachille Santus, Marina Saad, Giovanni Damiani, Vincenzo Patella & Dejan Radovanovic. (2019) Current and future targeted therapies for severe asthma: Managing treatment with biologics based on phenotypes and biomarkers. Pharmacological Research 146, pages 104296.
Crossref
Li-chun Tian, Qing-qing Zhu, Jun Li, Ai-jie Liu & Guang-rui Huang. (2019) Aerosol Inhalation-mediated Delivery of an Adeno-associated Virus 5-expressed Antagonistic Interleukin-4 Mutant Ameliorates Experimental Murine Asthma. Archives of Medical Research 50:6, pages 384-392.
Crossref
Ning Jiang, Yao Li, Ting Shu & Jing Wang. (2019) Cytokines and inflammation in adipogenesis: an updated review. Frontiers of Medicine 13:3, pages 314-329.
Crossref
H Huang, J-Y Hong, Y-J Wu, E-Y Wang, Z-Q Liu, B-H Cheng, L Mei, Z-G Liu, P-C Yang & P-Y Zheng. (2018) Vitamin D receptor interacts with NLRP3 to restrict the allergic response. Clinical and Experimental Immunology 194:1, pages 17-26.
Crossref
Yasutaka Mitamura, Satoshi Nunomura, Yasuhiro Nanri, Kazuhiko Arima, Tomohito Yoshihara, Kosaku Komiya, Shogo Fukuda, Hiroaki Takatori, Hiroshi Nakajima, Masutaka Furue & Kenji Izuhara. (2018) Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11. Journal of Biological Chemistry 293:38, pages 14646-14658.
Crossref
Jennifer R. Rainville, Mariya Tsyglakova & Georgia E. Hodes. (2018) Deciphering sex differences in the immune system and depression. Frontiers in Neuroendocrinology 50, pages 67-90.
Crossref
Chuanjun Huang, Zewen Zhang, Liuxin Wang, Ju Liu, Xiaodan Gong & Caiqing Zhang. (2018) ML-7 attenuates airway inflammation and remodeling via inhibiting the secretion of Th2 cytokines in mice model of asthma. Molecular Medicine Reports.
Crossref
Quan M. Nhu & Seema S. Aceves. (2017) Tissue Remodeling in Chronic Eosinophilic Esophageal Inflammation: Parallels in Asthma and Therapeutic Perspectives. Frontiers in Medicine 4.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.