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Review

Pathogenesis of adult onset still’s disease: current understanding and new insights

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Pages 965-976 | Received 03 Sep 2018, Accepted 04 Oct 2018, Published online: 12 Oct 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ilenia Di Cola, Paola Cipriani & Piero Ruscitti. (2022) Perspectives on the use of non-biological pharmacotherapy for adult-onset Still’s disease. Expert Opinion on Pharmacotherapy 23:14, pages 1577-1587.
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Piero Ruscitti, Alessandro Conforti, Viktoriya Pavlych & Roberto Giacomelli. (2019) Inhibiting inflammatory cytokines in adult onset Still’s disease. Current trends and new therapeutic perspectives. Expert Opinion on Orphan Drugs 7:12, pages 547-554.
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Ju-Yang Jung, Chang-Hee Suh & Hyoun-Ah Kim. (2019) The role of damage-associated molecular pattern for pathogenesis and biomarkers in adult-onset Still’s disease. Expert Review of Molecular Diagnostics 19:6, pages 459-468.
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Articles from other publishers (15)

Yudong Liu, Shulan Zhang, Chang-sheng Xia, Jiali Chen & Chunhong Fan. (2021) Elevated Granulocyte Colony-stimulating Factor Levels in Patients With Active Phase of Adult-onset Still Disease. The Journal of Rheumatology 48:5, pages 664-668.
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Yudong Liu, Changsheng Xia, Jiali Chen, Chunhong Fan & Jing He. (2021) Elevated circulating pro-inflammatory low-density granulocytes in adult-onset Still’s disease. Rheumatology 60:1, pages 297-303.
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Yuya Fujita, Tomoyuki Asano, Haruki Matsumoto, Naoki Matsuoka, Jumpei Temmoku, Shuzo Sato, Makiko Yashiro Furuya, Eiji Suzuki, Hiroshi Watanabe, Tomohiro Koga, Atsushi Kawakami & Kiyoshi Migita. (2020) Elevated serum levels of checkpoint molecules in patients with adult Still’s disease. Arthritis Research & Therapy 22:1.
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Piero Ruscitti, Onorina Berardicurti, Daniela Iacono, Ilenia Pantano, Vasiliki Liakouli, Francesco Caso, Giacomo Emmi, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Fabiola Atzeni, Federico Perosa, Raffaele Scarpa, Giuliana Guggino, Francesco Ciccia, Antonio Barile, Paola Cipriani & Roberto Giacomelli. (2020) Parenchymal lung disease in adult onset Still’s disease: an emergent marker of disease severity—characterisation and predictive factors from Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort of patients. Arthritis Research & Therapy 22:1.
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Huihui Chi, Haiyan Jin, Zhihong Wang, Tienan Feng, Ting Zeng, Hui Shi, Xinyao Wu, Liyan Wan, Jialin Teng, Yue Sun, Honglei Liu, Xiaobing Cheng, Junna Ye, Qiongyi Hu, Zhuochao Zhou, Jieyu Gu, Jinchao Jia, Tingting Liu, Xin Qiao, Chengde Yang & Yutong Su. (2020) Anxiety and depression in adult-onset Still’s disease patients and associations with health-related quality of life. Clinical Rheumatology 39:12, pages 3723-3732.
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Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Anna Rita Lizzi, Paola Cipriani, Yehuda Shoenfeld & Roberto Giacomelli. (2020) Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations. Scientific Reports 10:1.
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Paola Di Benedetto, Paola Cipriani, Daniela Iacono, Ilenia Pantano, Francesco Caso, Giacomo Emmi, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Fabiola Atzeni, Federico Perosa, Raffaele Scarpa, Giuliana Guggino, Francesco Ciccia, Roberto Giacomelli & Piero Ruscitti. (2020) Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still’s disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort. PLOS ONE 15:7, pages e0235326.
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Andrés Eduardo Prieto-Torres, Wilson Suárez-Molina & Jaime Iván Pantoja-Agreda. (2020) Adult Onset Still´s Disease (AOSD): A rare condition with a classic presentation. Case Report. Case reports 6:2, pages 100-108.
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Yi-Ming Chen, Wei-Ting Hung, Wan-Chun Chang, Chia-Wei Hsieh, Wen-Hung Chung, Joung-Liang Lan, Ning-Rong Gung, Yun-Shien Lee, Der-Yuan Chen & Shuen-Iu Hung. (2020) Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still’s Disease. Journal of Immunology Research 2020, pages 1-11.
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Piero Ruscitti, Francesco Ursini, Jurgen Sota, Roberto De Giorgio, Luca Cantarini & Roberto Giacomelli. (2020) The reduction of concomitant glucocorticoids dosage following treatment with IL-1 receptor antagonist in adult onset Still’s disease. A systematic review and meta-analysis of observational studies. Therapeutic Advances in Musculoskeletal Disease 12, pages 1759720X2093313.
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Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Daniela Iacono, Ilenia Pantano, Francesco Caso, Federico Perosa, Fabiola Atzeni, Francesco Paolo Cantatore, Raffaele Scarpa, Francesco Ciccia & Roberto Giacomelli. (2019) Prescribing motivations and patients’ characteristics related to the use of biologic drugs in adult-onset Still’s disease: analysis of a multicentre “real-life” cohort. Rheumatology International 40:1, pages 107-113.
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JU-YANG JUNG & HYOUN-AH KIM. (2019) The Role of Natural Killer Cells in Inflammation in Active Adult-onset Still Disease. The Journal of Rheumatology 46:10, pages 1253-1255.
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Bartlomiej Wawrzycki, Dorota Krasowska, Aldona Pietrzak, Ewa Wielosz, Maria Majdan & Torello Lotti. (2019) Urticarial rash, fever, and arthritis: A case of refractory Adult‐onset Still's disease with good response to tocilizumab. Dermatologic Therapy 32:5.
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Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Giuliana Guggino, Francesco Carubbi, Onorina Berardicurti, Francesco Ciccia & Roberto Giacomelli. (2019) Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study. Medicine 98:15, pages e15123.
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S. Chandrashekara, Vineeta Shobha, Vijay Rao, Anu Desai, Ramesh Jois, B. G. Dharmanand, Sharath Kumar, Pradeep Kumar, Chethana Dharmapalaiah, Kurugodu Mathada Mahendranath, Shiva Prasad, Manisha Ashwin Daware, Yogesh Singh, Uma Karjigi, S. Nagaraj & K. R. Anupama. (2019) Incidence of infection other than tuberculosis in patients with autoimmune rheumatic diseases treated with bDMARDs: a real-time clinical experience from India. Rheumatology International 39:3, pages 497-507.
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