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Review

New frontiers in precision medicine for sepsis-induced immunoparalysis

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Pages 251-263 | Received 30 Oct 2018, Accepted 19 Dec 2018, Published online: 07 Jan 2019

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Emily da Silva Córneo, Monique Michels & Felipe Dal-Pizzol. (2021) Sepsis, immunosuppression and the role of epigenetic mechanisms. Expert Review of Clinical Immunology 17:2, pages 169-176.
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Min Wang, Jun Feng, Daixing Zhou & Junshuai Wang. (2023) Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis. European Journal of Medical Research 28:1.
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Alexander Jerman, Jakob Gubenšek, Jernej Berden & Vanja Peršič. (2023) A matched case-control study on the effectiveness of extracorporeal cytokine adsorption in critically ill patients. Scientific Reports 13:1.
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David P. Schrijver, Rutger J. Röring, Jeroen Deckers, Anne de Dreu, Yohana C. Toner, Geoffrey Prevot, Bram Priem, Jazz Munitz, Eveline G. Nugraha, Yuri van Elsas, Anthony Azzun, Tom Anbergen, Laszlo A. Groh, Anouk M. D. Becker, Carlos Pérez-Medina, Roderick S. Oosterwijk, Boris Novakovic, Simone J. C. F. M. Moorlag, Aron Jansen, Peter Pickkers, Matthijs Kox, Thijs J. Beldman, Ewelina Kluza, Mandy M. T. van Leent, Abraham J. P. Teunissen, Roy van der Meel, Zahi A. Fayad, Leo A. B. Joosten, Edward A. Fisher, Maarten Merkx, Mihai G. Netea & Willem J. M. Mulder. (2023) Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells. Nature Biomedical Engineering 7:9, pages 1097-1112.
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C. Scorcella, R. Domizi, S. Amoroso, A. Carsetti, E. Casarotta, P. Castaldo, C. D’angelo, E. Damiani, F. Gasparri, A. Donati & E. Adrario. (2023) Pharmacogenetics in critical care: association between CYP3A5 rs776746 A/G genotype and acetaminophen response in sepsis and septic shock. BMC Anesthesiology 23:1.
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Jiale Yang, Fanghe Gong, Xuezhi Shi, Fanfan Wang, Jing Qian, Lulu Wan, Yi Chen, Huaisheng Chen & Huasheng Tong. (2023) A nomogram based on lymphocyte percentage for predicting hospital mortality in exertional heatstroke patients: a 13-year retrospective study. World Journal of Emergency Medicine 14:6, pages 434.
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Shanshan Liu, Changli Wang, Zhengyu Jiang, Xiaoming Deng & Lulong Bo. (2022) Tim-3 Blockade Decreases the Apoptosis of CD8+ T Cells and Reduces the Severity of Sepsis in Mice. Journal of Surgical Research 279, pages 8-16.
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Anne M. Drewry, Nicholas M. Mohr, Enyo A. Ablordeppey, Catherine M. Dalton, Rebecca J. Doctor, Brian M. Fuller, Marin H. Kollef & Richard S. Hotchkiss. (2022) Therapeutic Hyperthermia Is Associated With Improved Survival in Afebrile Critically Ill Patients With Sepsis: A Pilot Randomized Trial. Critical Care Medicine 50:6, pages 924-934.
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Nienke N. Hagedoorn, Pinar Kolukirik, Nicole M. A. Nagtzaam, Daan Nieboer, Sascha Verbruggen, Koen F. Joosten, Henriette Moll, Gertjan Driessen, Willem A. Dik & Clementien Vermont. (2021) Association of monocyte HLA-DR expression over time with secondary infection in critically ill children: a prospective observational study. European Journal of Pediatrics 181:3, pages 1133-1142.
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Tiffanie K. Jones, John P. Reilly, Brian J. Anderson, Todd A. Miano, Thomas G. Dunn, Ariel R. Weisman, Roseline Agyekum, Rui Feng, Caroline A.G. Ittner, Michael G.S. Shashaty & Nuala J. Meyer. (2022) Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis. Shock 57:1, pages 41-47.
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Steven J. Moioffer, Derek B. Danahy, Stephanie van de Wall, Isaac J. Jensen, Frances V. Sjaastad, Scott M. Anthony, John T. Harty, Thomas S. Griffith & Vladimir P. Badovinac. (2021) Severity of Sepsis Determines the Degree of Impairment Observed in Circulatory and Tissue-Resident Memory CD8 T Cell Populations. The Journal of Immunology 207:7, pages 1871-1881.
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Melanie A. Kimm, Christopher Klenk, Marianna Alunni-Fabbroni, Sophia Kästle, Matthias Stechele, Jens Ricke, Michel Eisenblätter & Moritz Wildgruber. (2021) Tumor-Associated Macrophages—Implications for Molecular Oncology and Imaging. Biomedicines 9:4, pages 374.
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Guus P. Leijte, Thomas Rimmelé, Matthijs Kox, Niklas Bruse, Céline Monard, Morgane Gossez, Guillaume Monneret, Peter Pickkers & Fabienne Venet. (2020) Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes. Critical Care 24:1.
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Chloé Albert Vega, Guy Oriol, François Bartolo, Jonathan Lopez, Alexandre Pachot, Thomas Rimmelé, Fabienne Venet, Véronique Leray, Guillaume Monneret, Benjamin Delwarde, Karen Brengel-Pesce, Julien Textoris, François Mallet & Sophie Trouillet-Assant. (2020) Deciphering heterogeneity of septic shock patients using immune functional assays: a proof of concept study. Scientific Reports 10:1.
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Manasi Nandi, Simon K. JacksonDuncan MacraeManu Shankar-HariJordi L. TremoledaElliot Lilley. (2020) Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs. Clinical Science 134:13, pages 1715-1734.
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Massimiliano Bonafè, Francesco Prattichizzo, Angelica Giuliani, Gianluca Storci, Jacopo Sabbatinelli & Fabiola Olivieri. (2020) Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. Cytokine & Growth Factor Reviews 53, pages 33-37.
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Jesús Beltrán-García, Rebeca Osca-Verdegal, Carlos Romá-Mateo, Nieves Carbonell, José Ferreres, María Rodríguez, Sandra Mulet, Eva García-López, Federico V Pallardó & José Luis García-Giménez. (2020) Epigenetic biomarkers for human sepsis and septic shock: insights from immunosuppression. Epigenomics 12:7, pages 617-646.
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Laure F. Pittet, Mohamed Abbas, Claire-Anne Siegrist & Didier Pittet. (2019) Missed vaccinations and critical care admission: all you may wish to know or rediscover—a narrative review. Intensive Care Medicine 46:2, pages 202-214.
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