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Expert Opinion on Drug Discovery Volume 12, 2017 - Issue 7
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Review

The impact of genetics on future drug discovery in schizophrenia

Mitsuyuki MatsumotoUnit 2, Candidate Discovery Science Labs., Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Ibaraki, JapanCorrespondence[email protected]
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,
Noah M. WaltonLa Jolla Laboratory, Astellas Research Institute of America LLC, San Diego, CA, USAView further author information
,
Hiroshi YamadaLa Jolla Laboratory, Astellas Research Institute of America LLC, San Diego, CA, USAView further author information
,
Yuji KondoUnit 2, Candidate Discovery Science Labs., Drug Discovery Research, Astellas Pharma Inc., Tsukuba, Ibaraki, JapanView further author information
,
Gerard J. MarekDevelopment Medical Sciences, Astellas Pharma Global Development, Northbrook, IL, USAView further author information
&
Katsunori TajindaLa Jolla Laboratory, Astellas Research Institute of America LLC, San Diego, CA, USAView further author information
Pages 673-686 | Received 24 Jan 2017, Accepted 25 Apr 2017, Published online: 18 May 2017

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Marinos G. Sotiropoulos, Eleni Poulogiannopoulou, Foteini Delis, Christina Dalla, Katerina Antoniou & Nikolaos Kokras. (2021) Innovative screening models for the discovery of new schizophrenia drug therapies: an integrated approach. Expert Opinion on Drug Discovery 16:7, pages 791-806.
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Giulio Piluso, Palmiero Monteleone, Silvana Galderisi, Teresa Giugliano, Alessandro Bertolino, Paola Rocca, Alessandro Rossi, Armida Mucci, Eugenio Aguglia, Ileana Andriola, Antonello Bellomo, Anna Comparelli, Francesco Gambi, Andrea Fagiolini, Carlo Marchesi, Rita Roncone, Emilio Sacchetti, Paolo Santonastaso, Alberto Siracusano, Paolo Stratta, Alfonso Tortorella, Luca Steardo$suffix/text()$suffix/text(), Paola Bucci, Vincenzo Nigro & Mario Maj. (2019) Assessment of de novo copy-number variations in Italian patients with schizophrenia: Detection of putative mutations involving regulatory enhancer elements. The World Journal of Biological Psychiatry 20:2, pages 126-136.
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Articles from other publishers (9)

Robert E Featherstone, Takeshi Shimada, Lindsey M Crown, Olya Melnychenko, Janice Yi, Mitsuyuki Matsumoto, Katsunori Tajinda, Takuma Mihara, Megumi Adachi & Steven J Siegel. (2022) Calcium/calmodulin-dependent protein kinase IIα heterozygous knockout mice show electroencephalogram and behavioral changes characteristic of a subpopulation of schizophrenia and intellectual impairment. Neuroscience 499, pages 104-117.
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Mitsuteru Nakamura, Kenny Ye, Mariel Barbachan e Silva, Takahira Yamauchi, Daniel J. Hoeppner, Amir Fayyazuddin, Gina Kang, Emi A. Yuda, Masako Nagashima, Shingo Enomoto, Takeshi Hiramoto, Richard Sharp, Itaru Kaneko, Katsunori Tajinda, Megumi Adachi, Takuma Mihara, Shinichi Tokuno, Mark A. Geyer, Pilib Ó Broin, Mitsuyuki Matsumoto & Noboru Hiroi. (2021) Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion. Molecular Psychiatry 26:11, pages 6578-6588.
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Saurav Seshadri, Daniel J. Hoeppner & Katsunori Tajinda. (2020) Calcium Imaging in Drug Discovery for Psychiatric Disorders. Frontiers in Psychiatry 11.
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Sokichi Honda, Mitsuyuki Matsumoto, Katsunori Tajinda & Takuma Mihara. (2020) Enhancing Clinical Trials Through Synergistic Gamma Power Analysis. Frontiers in Psychiatry 11.
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Luis A. Williams, Vaibhav Joshi, Michael Murphy, John Ferrante, Christopher A. Werley, Theodore Brookings, Owen McManus, Johannes Grosse, Ceri H. Davies & Graham T. Dempsey. (2019) Scalable Measurements of Intrinsic Excitability in Human iPS Cell-Derived Excitatory Neurons Using All-Optical Electrophysiology. Neurochemical Research 44:3, pages 714-725.
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Corona Solana, Diana Pereira & Raquel Tarazona. (2018) Early Senescence and Leukocyte Telomere Shortening in SCHIZOPHRENIA: A Role for Cytomegalovirus Infection?. Brain Sciences 8:10, pages 188.
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Esmaeil Shahsavand Ananloo. 2018. Psychotic Disorders - An Update. Psychotic Disorders - An Update.
Pronab Ganguly, Abdrabo Soliman & Ahmed A. Moustafa. (2018) Holistic Management of Schizophrenia Symptoms Using Pharmacological and Non-pharmacological Treatment. Frontiers in Public Health 6.
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Haitao Wang, Jiangping Xu, Philip Lazarovici & Wenhua Zheng. (2017) Dysbindin-1 Involvement in the Etiology of Schizophrenia. International Journal of Molecular Sciences 18:10, pages 2044.
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