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Expert Opinion on Drug Discovery Volume 13, 2018 - Issue 10
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Review

Designing safer analgesics: a focus on μ-opioid receptor pathways

Joseph V. Pergolizzi Jr.NEMA Research, Inc, Naples, FL, USAView further author information
,
Jo Ann LeQuangNEMA Research, Inc, Naples, FL, USAView further author information
,
Robert Taylor Jr.NEMA Research, Inc, Naples, FL, USAView further author information
,
Michael H. OssipovDepartment of Pharmacology, University of Arizona College of Medicine, Tucson, AZ, USAView further author information
,
Daniel ColucciDepartment of Bioengineering, Northeastern University, Boston, MA, USAView further author information
&
Robert B. RaffaUniversity of Arizona College of Pharmacy, Tucson, AZ, USA;Temple University School of Pharmacy, Philadelphia, PA, USACorrespondence[email protected]
View further author information
Pages 965-972 | Received 22 May 2018, Accepted 10 Aug 2018, Published online: 03 Sep 2018

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Filippo Caraci, Flaminia Coluzzi, Franco Marinangeli, Sebastiano Mercadante, Giuseppe Rinonapoli, Patrizia Romualdi, Mariaflavia Nicora & Anthony H. Dickenson. (2020) Modulation of sensitization processes in the management of pain and the importance of descending pathways: a role for tapentadol?. Current Medical Research and Opinion 36:6, pages 1015-1024.
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Filippo Caraci, Flaminia Coluzzi, Franco Marinangeli, Sebastiano Mercadante, Giuseppe Rinonapoli, Patrizia Romualdi, Mariaflavia Nicora & Anthony H. Dickenson. (2020) Modulation of sensitization processes in the management of pain and the importance of descending pathways: a role for tapentadol?. Current Medical Research and Opinion 36:5, pages (I)-(XVII).
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Rajiv Balyan, David Hahn, Henry Huang & Vidya Chidambaran. (2020) Pharmacokinetic and pharmacodynamic considerations in developing a response to the opioid epidemic. Expert Opinion on Drug Metabolism & Toxicology 16:2, pages 125-141.
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Hans G Kress & Flaminia Coluzzi. (2019) Tapentadol in the management of cancer pain: current evidence and future perspectives. Journal of Pain Research 12, pages 1553-1560.
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Flaminia Coluzzi, Enrico Polati, Ulderico Freo & Mariagrazia Grilli. (2019) Tapentadol: an effective option for the treatment of back pain. Journal of Pain Research 12, pages 1521-1528.
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Anthony H Dickenson & Hans G Kress. (2019) Tapentadol: a new option for the treatment of cancer and noncancer pains. Journal of Pain Research 12, pages 1509-1511.
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Ulderico Freo, Patrizia Romualdi & Hans G Kress. (2019) Tapentadol for neuropathic pain: a review of clinical studies. Journal of Pain Research 12, pages 1537-1551.
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Lorenzo Panella, Giuseppe Rinonapoli & Stefano Coaccioli. (2019) Where should analgesia lead to? Quality of life and functional recovery with tapentadol. Journal of Pain Research 12, pages 1561-1567.
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Enrico Polati, Pier Luigi Canonico, Vittorio Schweiger & Massimo Collino. (2019) Tapentadol: an overview of the safety profile. Journal of Pain Research 12, pages 1569-1576.
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