https://orcid.org/0000-0002-7444-9359
Citations (24)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Kathryn E. Oliver, Marianne S. Carlon, Nicoletta Pedemonte & Miquéias Lopes-Pacheco. (2023) The revolution of personalized pharmacotherapies for cystic fibrosis: what does the future hold?. Expert Opinion on Pharmacotherapy 24:14, pages 1545-1565.
Read now
Read now
Madalena C Pinto, Iris A L Silva, Miriam F Figueira, Margarida D Amaral & Miquéias Lopes-Pacheco. (2021) Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis. Journal of Experimental Pharmacology 13, pages 693-723.
Read now
Read now
Articles from other publishers (22)
Maryam M.J. Fallatah, Fiona V. Law, Warren A. Chow & Peter Kaiser. (2023) Small-molecule correctors and stabilizers to target p53. Trends in Pharmacological Sciences 44:5, pages 274-289.
Crossref
Crossref
Miquéias Lopes-Pacheco & Patricia R. M. Rocco. (2023) Functional enhancement strategies to potentiate the therapeutic properties of mesenchymal stromal cells for respiratory diseases. Frontiers in Pharmacology 14.
Crossref
Crossref
Mafalda Bacalhau, Mariana Camargo, Grace A. V. Magalhães-Ghiotto, Sybelle Drumond, Carlos Henrique M. Castelletti & Miquéias Lopes-Pacheco. (2023) Elexacaftor-Tezacaftor-Ivacaftor: A Life-Changing Triple Combination of CFTR Modulator Drugs for Cystic Fibrosis. Pharmaceuticals 16:3, pages 410.
Crossref
Crossref
Anabela S. Ramalho, Felice Amato & Martina Gentzsch. (2023) Patient-derived cell models for personalized medicine approaches in cystic fibrosis. Journal of Cystic Fibrosis 22, pages S32-S38.
Crossref
Crossref
Patricia Scott, Shuo Wang, Guillaume Onyeaghala, Nathan Pankratz, Timothy Starr & Anna E. Prizment. (2023) Lower Expression of CFTR Is Associated with Higher Mortality in a Meta-Analysis of Individuals with Colorectal Cancer. Cancers 15:3, pages 989.
Crossref
Crossref
Jesús M. Meléndez-Montañez & Wilfredo De Jesús-Rojas. (2023) CFTR-Related Metabolic Syndrome: Genetic Variants Increasing Pancreatitis Risk in the Pediatric Puerto Rican Population. Children 10:2, pages 280.
Crossref
Crossref
Mafalda Bacalhau, Filipa C. Ferreira, Iris A. L. Silva, Camilla D. Buarque, Margarida D. Amaral & Miquéias Lopes-Pacheco. (2023) Additive Potentiation of R334W-CFTR Function by Novel Small Molecules. Journal of Personalized Medicine 13:1, pages 102.
Crossref
Crossref
Sacha Spelier, Eyleen de Poel, Georgia N. Ithakisiou, Sylvia W.F. Suen, Marne C. Hagemeijer, Danya Muilwijk, Annelotte M. Vonk, Jesse E. Brunsveld, Evelien Kruisselbrink, Cornelis K. van der Ent & Jeffrey M. Beekman. (2023) High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing. ERJ Open Research 9:1, pages 00495-2022.
Crossref
Crossref
Mafalda Bacalhau, Filipa C. Ferreira, Arthur Kmit, Felipe R. Souza, Verônica D. da Silva, André S. Pimentel, Margarida D. Amaral, Camilla D. Buarque & Miquéias Lopes-Pacheco. (2023) Identification of novel F508del-CFTR traffic correctors among triazole derivatives. European Journal of Pharmacology 938, pages 175396.
Crossref
Crossref
Anya T. Joynt, Garry R. Cutting & Neeraj Sharma. (2022) Genetics of Cystic Fibrosis. Clinics in Chest Medicine 43:4, pages 591-602.
Crossref
Crossref
Katelin M. Allan, Miro A. Astore, Laura K. Fawcett, Sharon L. Wong, Po-Chia Chen, Renate Griffith, Adam Jaffe, Serdar Kuyucak & Shafagh A. Waters. (2022) S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy in vivo and in vitro in matched pediatric patient-derived cell models. Frontiers in Pediatrics 10.
Crossref
Crossref
Alyssa Bowling, Alice Eastman, Christian Merlo, Gabrielle Lin, Natalie West, Shivani Patel, Garry Cutting & Neeraj Sharma. (2022) Downstream Alternate Start Site Allows N-Terminal Nonsense Variants to Escape NMD and Results in Functional Recovery by Readthrough and Modulator Combination. Journal of Personalized Medicine 12:9, pages 1448.
Crossref
Crossref
Chiara Papi, Jessica Gasparello, Matteo Zurlo, Alex Manicardi, Roberto Corradini, Giulio Cabrini, Roberto Gambari & Alessia Finotti. (2022) Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene. International Journal of Molecular Sciences 23:16, pages 9348.
Crossref
Crossref
Iris A. L. Silva, Onofrio Laselva & Miquéias Lopes-Pacheco. (2022) Advances in Preclinical In Vitro Models for the Translation of Precision Medicine for Cystic Fibrosis. Journal of Personalized Medicine 12:8, pages 1321.
Crossref
Crossref
John A. King, Anna-Louise Nichols, Sian Bentley, Siobhan B. Carr & Jane C. Davies. (2022) An Update on CFTR Modulators as New Therapies for Cystic Fibrosis. Pediatric Drugs 24:4, pages 321-333.
Crossref
Crossref
Tamorah Lewis, Kelly C. Wade & Jonathan M. Davis. (2022) Challenges and opportunities for improving access to approved neonatal drugs and devices. Journal of Perinatology 42:6, pages 825-828.
Crossref
Crossref
Amanda Centorame, Daciana Catalina Dumut, Mina Youssef, Martin Ondra, Irenej Kianicka, Juhi Shah, Radu Alexandru Paun, Tomas Ozdian, John W. Hanrahan, Ekaterina Gusev, Basil Petrof, Marian Hajduch, Radu Pislariu, Juan Bautista De Sanctis & Danuta Radzioch. (2022) Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease. Frontiers in Pharmacology 13.
Crossref
Crossref
Fabiana Ciciriello, Marcel J. C. Bijvelds, Federico Alghisi, Kelly F. Meijsen, Luca Cristiani, Claudio Sorio, Paola Melotti, Alessandro G. Fiocchi, Vincenzina Lucidi & Hugo R. De Jonge. (2022) Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers. Journal of Personalized Medicine 12:4, pages 632.
Crossref
Crossref
Miquéias Lopes-Pacheco, Mafalda Bacalhau, Sofia S. Ramalho, Iris A. L. Silva, Filipa C. Ferreira, Graeme W. Carlile, David Y. Thomas, Carlos M. Farinha, John W. Hanrahan & Margarida D. Amaral. (2022) Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A. Cells 11:1, pages 136.
Crossref
Crossref
Ana M. Matos, Peter Jordan & Paulo Matos. (2021) Treatment of Polarized Cystic Fibrosis Airway Cells With HGF Prevents VX-661-Rescued F508del-CFTR Destabilization Caused by Prolonged Co-exposure to VX-770. Frontiers in Molecular Biosciences 8.
Crossref
Crossref
Carla M. P. Ribeiro & Martina Gentzsch. (2021) Impact of Airway Inflammation on the Efficacy of CFTR Modulators. Cells 10:11, pages 3260.
Crossref
Crossref
Guido Veit, Tony Velkov, Haijin Xu, Nathalie Vadeboncoeur, Lara Bilodeau, Elias Matouk & Gergely Lukacs. (2021) A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants. Journal of Personalized Medicine 11:7, pages 643.
Crossref
Crossref