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Expert Opinion on Drug Discovery Volume 17, 2022 - Issue 4

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Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues

Sebastian C. Cosgrovea Lennard-Jones Laboratory, School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire, UK;b Centre for Glycoscience Research, Keele University, Keele, Staffordshire, UKCorrespondence[email protected]

https://orcid.org/0000-0001-9541-7201 View further author information

Gavin J. Millera Lennard-Jones Laboratory, School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire, UK;b Centre for Glycoscience Research, Keele University, Keele, Staffordshire, UKCorrespondence[email protected]

https://orcid.org/0000-0001-6533-3306 View further author information

Pages 355-364 | Received 14 Dec 2021, Accepted 04 Feb 2022, Published online: 17 Feb 2022

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https://doi.org/10.1080/17460441.2022.2039620
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Felix Kaspar, Felix Brandt, Sarah Westarp, Lea Eilert, Sebastian Kemper, Anke Kurreck, Peter Neubauer, Christoph R. Jacob & Anett Schallmey. (2023) Biased Borate Esterification during Nucleoside Phosphorylase‐Catalyzed Reactions: Apparent Equilibrium Shifts and Kinetic Implications**. Angewandte Chemie International Edition 62:20.
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Felix Kaspar, Felix Brandt, Sarah Westarp, Lea Eilert, Sebastian Kemper, Anke Kurreck, Peter Neubauer, Christoph R. Jacob & Anett Schallmey. (2023) Einseitige Borat‐Veresterung während enzymatischer Nukleosid‐phosphorolyse: Scheinbare Gleichgewichtsverschiebungen und kinetische Auswirkungen**. Angewandte Chemie 135:20.
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Michele Crotti, Marina S. Robescu, Juan M. Bolivar, Daniela Ubiali, Lorena Wilson & Martina L. Contente. (2023) What’s new in flow biocatalysis? A snapshot of 2020–2022. Frontiers in Catalysis 3.
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Jonathan P. Dolan, Sebastian C. Cosgrove & Gavin J. Miller. (2022) Biocatalytic Approaches to Building Blocks for Enzymatic and Chemical Glycan Synthesis. JACS Au 3:1, pages 47-61.
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Caecilie M. M. Benckendorff, Valentyna D. Slyusarchuk, Ningwu Huang, Marcelo A. Lima, Mark Smith & Gavin J. Miller. (2022) Synthesis of fluorinated carbocyclic pyrimidine nucleoside analogues. Organic & Biomolecular Chemistry 20:47, pages 9469-9489.
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Olga S. Smirnova, Maria Ya. Berzina, Ilya V. Fateev, Barbara Z. Eletskaya, Maria A. Kostromina, Alexey L. Kaushin, Alexander S. Paramonov, Alexander N. Prutkov, Andrey V. Matveev, Lyubov E. Grebenkina, Mikhail V. Chudinov, Valeria L. Andronova, Georgiy A. Galegov, Petr G. Deryabin, Anatoly I. Miroshnikov, Roman S. Esipov & Irina D. Konstantinova. (2022) Chemo-enzymatic synthesis of 5-substituted ribavirin analogs: Unexpected cooperative effect in the interaction of 5-alkyloxymethyl 1,2,4-triazol-3-carboxamides with E. coli purine nucleoside phosphorylase active site. Sustainable Chemistry and Pharmacy 30, pages 100881.
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Sarah Westarp, Felix Kaspar, Peter Neubauer & Anke Kurreck. (2022) Industrial potential of the enzymatic synthesis of nucleoside analogs: existing challenges and perspectives. Current Opinion in Biotechnology 78, pages 102829.
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Ana I. Benítez-Mateos, Calvin Klein, David Roura Padrosa & Francesca Paradisi. (2022) A novel thymidine phosphorylase to synthesize (halogenated) anticancer and antiviral nucleoside drugs in continuous flow. Catalysis Science & Technology 12:20, pages 6231-6238.
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Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues

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Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues

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