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Expert Review of Hematology Volume 10, 2017 - Issue 8
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Review

Bendamustine hydrochloride in patients with B-cell malignancies who have comorbidities – is there an optimal dose?

Max J. GordonDepartment of Internal Medicine, Oregon Health & Science University, Portland, OR, USAView further author information
,
Lionel D. LewisSection of Clinical Pharmacology, Department of Medicine, The Geisel School of Medicine at Dartmouth and The Norris Cotton Cancer Center, Lebanon, NH, USAView further author information
,
Jennifer R. BrownDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USACorrespondence[email protected]
View further author information
&
Alexey V. DanilovDepartment of Internal Medicine, Oregon Health & Science University, Portland, OR, USA;Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USACorrespondence[email protected]
View further author information
Pages 707-718 | Received 12 Jan 2017, Accepted 29 Jun 2017, Published online: 10 Jul 2017

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Graeme A.M. Fraser, Asher Chanan-Khan, Fatih Demirkan, Rodrigo Santucci Silva, Sebastian Grosicki, Ann Janssens, Jiri Mayer, Nancy L. Bartlett, Marie-Sarah Dilhuydy, Javier Loscertales, Abraham Avigdor, Simon Rule, Olga Samoilova, Miguel A. Pavlovsky, Andre Goy, Anthony Mato, Michael Hallek, Mariya Salman, Monelle Tamegnon, Steven Sun, Anne Connor, Kerri Nottage, Natasha Schuier, Sriram Balasubramanian, Angela Howes & Paula Cramer. (2020) Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma. Leukemia & Lymphoma 61:13, pages 3188-3197.
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Articles from other publishers (7)

Manabu SuzukiDaisuke KoyamaShohei IkedaMasumi SukegawaMayumi TeshirogiKyohei Misawa & Saburo Tsunoda. (2022) Serum IgG and lymphocyte counts are useful for the early detection of infection in patients receiving bendamustine-rituximab therapy. Journal of Clinical and Experimental Hematopathology 62:2, pages 91-98.
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Natalia Timofeeva & Varsha Gandhi. (2021) Ibrutinib combinations in CLL therapy: scientific rationale and clinical results. Blood Cancer Journal 11:4.
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Irene Dogliotti, Simone Ragaini, Francesco Vassallo, Elia Boccellato, Gabriele De Luca, Francesca Perutelli, Carola Boccomini, Michele Clerico, Barbara Botto, Daniele Grimaldi, Lorella Orsucci, Simone Ferrero, Candida Vitale, Dario Ferrero, Marta Coscia & Federica Cavallo. (2021) Real Life Use of Bendamustine in Elderly Patients with Lymphoid Neoplasia. Journal of Personalized Medicine 11:4, pages 249.
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Eriong Lee‐Vergés, Bola S. Hanna, Haniyeh Yazdanparast, Vanina Rodríguez, Marta Leonor Rodríguez, Ariadna Giró, Anna Vidal‐Crespo, Laia Rosich, Virginia Amador, Marta Aymerich, Neus Villamor, Julio Delgado, Peter Lichter, Patricia Pérez‐Galán, Mònica López‐Guerra, Elías Campo, Martina Seiffert & Dolors Colomer. (2019) Selective BTK inhibition improves bendamustine therapy response and normalizes immune effector functions in chronic lymphocytic leukemia. International Journal of Cancer 144:11, pages 2762-2773.
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G. Fraser, P. Cramer, F. Demirkan, R. Santucci Silva, S. Grosicki, A. Pristupa, A. Janssens, J. Mayer, N. L. Bartlett, M.-S. Dilhuydy, H. Pylypenko, J. Loscertales, A. Avigdor, S. Rule, D. Villa, O. Samoilova, P. Panagiotidis, A. Goy, M. A. Pavlovsky, C. Karlsson, M. Hallek, M. Mahler, M. Salman, S. Sun, C. Phelps, S. Balasubramanian, A. Howes & A. Chanan-Khan. (2018) Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine, and rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma. Leukemia 33:4, pages 969-980.
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Max J. Gordon, Michael Churnetski, Hamood Alqahtani, Xavier Rivera, Adam Kittai, Stephen M. Amrock, Spencer James, Sheila Hoff, Sudhir Manda, Stephen E. Spurgeon, Michael Choi, Jonathon B. Cohen, Daniel Persky & Alexey V. Danilov. (2018) Comorbidities predict inferior outcomes in chronic lymphocytic leukemia treated with ibrutinib. Cancer 124:15, pages 3192-3200.
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Jennifer A. Woyach. (2018) What is the optimal management of older CLL patients?. Best Practice & Research Clinical Haematology 31:1, pages 83-89.
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