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Expert Review of Hematology Volume 11, 2018 - Issue 12
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Drug Profile

Venetoclax for the treatment of multiple myeloma

Iuliana VaxmanDivision of Hematology, Mayo Clinic, Rochester, MN, USA;Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center Petah- Tikva, Israel Sackler Faculty of Medicine Tel-Aviv University, Tel-Aviv, IsraelORCID Iconhttp://orcid.org/0000-0002-8390-064XView further author information
ORCID Icon,
M Hasib SidiqiDivision of Hematology, Mayo Clinic, Rochester, MN, USAORCID Iconhttp://orcid.org/0000-0003-1089-3853View further author information
ORCID Icon &
Morie GertzDivision of Hematology, Mayo Clinic, Rochester, MN, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-3853-5196View further author information
ORCID Icon
Pages 915-920 | Received 09 Sep 2018, Accepted 13 Nov 2018, Published online: 06 Dec 2018

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Xavier Leleu, Ajai Chari, Shambavi Richard, Monica Khurana, Akeem Yusuf & Saad Z. Usmani. (2021) A combination of carfilzomib, dexamethasone, and daratumumab for treatment of adult patients with relapsed/refractory multiple myeloma in two dosing regimens: once-weekly and twice-weekly. Expert Review of Hematology 14:12, pages 1049-1058.
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Albert Oriol, Laura Abril, Gladys Ibarra & Alicia Senin. (2020) Limited treatment options in refractory multiple myeloma: promising therapeutic developments. Expert Review of Anticancer Therapy 20:1, pages 31-44.
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Pellegrino Musto, Teodora Statuto, Luciana Valvano, Vitina Grieco, Filomena Nozza, Gabriella Vona, Giovanni Battista Bochicchio, Francesco La Rocca & Fiorella D’Auria. (2019) An update on biology, diagnosis and treatment of primary plasma cell leukemia. Expert Review of Hematology 12:4, pages 245-253.
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Articles from other publishers (21)

Behnam Noorani, Rajeev M. Menon, Xin Chen, Kennan C. Marsh, Weize Huang, Shelly Gupta, Edyta Dobkowska, Thomas Marbury & Ahmed Hamed Salem. (2023) Venetoclax pharmacokinetics in participants with end‐stage renal disease undergoing haemodialysis. British Journal of Clinical Pharmacology.
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Danai Dima, Fauzia Ullah, Sandra Mazzoni, Louis Williams, Beth Faiman, Austin Kurkowski, Chakra Chaulagain, Shahzad Raza, Christy Samaras, Jason Valent, Jack Khouri & Faiz Anwer. (2023) Management of Relapsed–Refractory Multiple Myeloma in the Era of Advanced Therapies: Evidence-Based Recommendations for Routine Clinical Practice. Cancers 15:7, pages 2160.
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Eyal Lebel, Efstathios Kastritis, Giovanni Palladini, Paolo Milani, Foteini Theodorakakou, Shlomzion Aumann, Noa Lavi, Liat Shargian, Hila Magen, Yael Cohen, Moshe E. Gatt & Iuliana Vaxman. (2023) Venetoclax in Relapse/Refractory AL Amyloidosis—A Multicenter International Retrospective Real-World Study. Cancers 15:6, pages 1710.
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Liqin Cao, Qingxiao Chen, Huiyao Gu, Yi Li, Wen Cao, Yang Liu, Jianwei Qu, Yifan Hou, Jing Chen, Enfan Zhang, Jingsong He & Zhen Cai. (2022) Chidamide and venetoclax synergistically exert cytotoxicity on multiple myeloma by upregulating BIM expression. Clinical Epigenetics 14:1.
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Loes M. Stevers, Madita Wolter, Graeme W. Carlile, Dwight Macdonald, Luc Richard, Frank Gielkens, John W. Hanrahan, David Y. Thomas, Sai Kumar Chakka, Mark L. Peterson, Helmut Thomas, Luc Brunsveld & Christian Ottmann. (2022) Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR. Nature Communications 13:1.
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Michael D. Diamantidis, Sofia Papadaki & Evdoxia Hatjiharissi. (2022) Exploring the current molecular landscape and management of multiple myeloma patients with the t(11;14) translocation. Frontiers in Oncology 12.
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Mario Morales-Martínez & Mario I. Vega. (2022) Roles and Regulation of BCL-xL in Hematological Malignancies. International Journal of Molecular Sciences 23:4, pages 2193.
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Sachi Singhal & Shaji Kumar. (2022) Oral Therapies for Multiple Myeloma. Oncology & Haematology 18:2, pages 139.
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Ahmed Hamed Salem, Zhi-Fu Tao, Orlando F. Bueno, Jie Chen, Shuang Chen, Rohinton Edalji, Steven W. Elmore, Keith M. Fournier, Kaid C. Harper, Richard Hong, Gary J. Jenkins, Jianguo Ji, Russell A. Judge, John C. Kalvass, Russell C. Klix, Yi-Yin Ku, Joel D. Leverson, Richard A. Marks, Kennan C. Marsh, Rajeev M. Menon, Chang H. Park, Darren C. Phillips, Yu-Ming Pu, Saul H. Rosenberg, Yeshwant D. Sanzgiri, Ahmad Y. Sheikh, Yi Shi, Deanne Stolarik, Ahmed A. Suleiman, Xilu Wang, Geoff G.Z. Zhang, Nathaniel D. Catron & Andrew J. Souers. (2021) Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Molecular Cancer Therapeutics 20:6, pages 999-1008.
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M. Hasib Sidiqi & Morie A. Gertz. (2021) Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2021. Blood Cancer Journal 11:5.
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Jan M. GriffinHannah RosenblumMathew S. Maurer. (2021) Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis. Circulation Research 128:10, pages 1554-1575.
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Anastazja Poczta, Aneta Rogalska & Agnieszka Marczak. (2021) Treatment of Multiple Myeloma and the Role of Melphalan in the Era of Modern Therapies—Current Research and Clinical Approaches. Journal of Clinical Medicine 10:9, pages 1841.
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Grace Lassiter, Cole Bergeron, Ryan Guedry, Julia Cucarola, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye, Giustino Varrassi, Omar Viswanath & Ivan Urits. (2021) Belantamab Mafodotin to Treat Multiple Myeloma: A Comprehensive Review of Disease, Drug Efficacy and Side Effects. Current Oncology 28:1, pages 640-660.
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Mohammed Isaac Abu Zaanona & Priyank Patel. (2021) Plasma cell leukaemia with t(11;14) not responsive to venetoclax. BMJ Case Reports 14:1, pages e238641.
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Tizhi Wu, Zhen Qin, Yucheng Tian, Jubo Wang, Chenxi Xu, Zhiyu Li & Jinlei Bian. (2020) Recent Developments in the Biology and Medicinal Chemistry of CDK9 Inhibitors: An Update. Journal of Medicinal Chemistry 63:22, pages 13228-13257.
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Youngil Koh. (2020) AL amyloidosis: advances in diagnosis and management. BLOOD RESEARCH 55:S1, pages S54-S57.
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Andreas Strasser & David L. Vaux. (2020) Cell Death in the Origin and Treatment of Cancer. Molecular Cell 78:6, pages 1045-1054.
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Heba F. Ashour, Laila A. Abou-zeid, Magda A. -A. El-Sayed & Khalid B. Selim. (2020) 1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226. European Journal of Medicinal Chemistry 189, pages 112062.
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M. A. Baertsch, R. Lutz, M. S. Raab, N. Weinhold & H. Goldschmidt. (2019) Meeting report of the 7th Heidelberg Myeloma Workshop: today and tomorrow. Journal of Cancer Research and Clinical Oncology 145:10, pages 2445-2455.
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Elena Follini, Matteo Marchesini & Giovanni Roti. (2019) Strategies to Overcome Resistance Mechanisms in T-Cell Acute Lymphoblastic Leukemia. International Journal of Molecular Sciences 20:12, pages 3021.
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Corrado Girmenia. (2019) New hematologic populations at risk of invasive aspergillosis: focus on new targeted, biological, and cellular therapies. F1000Research 8, pages 1202.
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