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Expert Review of Hematology Volume 12, 2019 - Issue 3
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Review

Management of cytokine release syndrome and neurotoxicity in chimeric antigen receptor (CAR) T cell therapy

Utkarsh H. AcharyaDivision of Medical Oncology, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA, USA;Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA;Divisions of Hematologic Malignancies & Immune Effector Cell Therapy, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-5920-2796View further author information
ORCID Icon,
Tejaswini DhawaleDivision of Hematology, Department of Medicine, University of Washington, Seattle, WA, USAView further author information
,
Seongseok YunDepartment of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USAView further author information
,
Caron A. JacobsonDivisions of Hematologic Malignancies & Immune Effector Cell Therapy, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USAView further author information
,
Julio C. ChavezDepartment of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USAView further author information
,
Jorge D. RamosDivision of Medical Oncology, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA, USA;Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USAView further author information
,
Jacob AppelbaumDivision of Medical Oncology, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA, USA;Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USAView further author information
&
David G. MaloneyDivision of Medical Oncology, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA, USA;Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USAORCID Iconhttp://orcid.org/0000-0002-8477-6919View further author information
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Pages 195-205 | Received 08 Dec 2018, Accepted 18 Feb 2019, Published online: 18 Mar 2019

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Chengyuan Gu, Qian Wu, Jingren Zhang, Liqing Kang, Lei Yu, Huiying Qiu, Depei Wu, Suning Chen & Xiaofei Yang. (2023) Successful treatment of severe cytokine release syndrome after CAR-T therapy by ruxolitinib without compromising CAR-T efficacy. Leukemia & Lymphoma 64:2, pages 495-498.
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Omar Castaneda-Puglianini & Julio C Chavez. (2021) Assessing and Management of Neurotoxicity After CAR-T Therapy in Diffuse Large B-Cell Lymphoma. Journal of Blood Medicine 12, pages 775-783.
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Andrew Schaefer, Ying Huang, Adam Kittai, Joseph E Maakaron, Caner Saygin, Jonathan Brammer, Sam Penza, Ayman Saad, Samantha M Jaglowski & Basem M William. (2021) Cytopenias After CD19 Chimeric Antigen Receptor T-Cells (CAR-T) Therapy for Diffuse Large B-Cell Lymphomas or Transformed Follicular Lymphoma: A Single Institution Experience. Cancer Management and Research 13, pages 8901-8906.
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