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Expert Review of Hematology Volume 14, 2021 - Issue 7
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Review

Oral ferroportin inhibitor vamifeport for improving iron homeostasis and erythropoiesis in β-thalassemia: current evidence and future clinical development

John Portera Professor of Haematology, Department of Haematology, University College London, Consultant in Haematology, University College London Hospitals and Head of Joint UCLH and Whittington Hospital Red Cell Unit, London, UKORCID Iconhttps://orcid.org/0000-0003-3000-9359View further author information
ORCID Icon,
Ali Taherb Professor of Medicine, Hematology and Oncology, Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonORCID Iconhttps://orcid.org/0000-0001-8515-2238View further author information
ORCID Icon,
Vip Viprakasitc Professor of Pediatrics, Director, Thalassemia Research Program, Director, SiCORE in Advanced Cell & Gene Therapy Center (SiCORE-ACGT), Division of Hematology and Oncology, Department of Pediatrics & Siriraj Thalassemia Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandORCID Iconhttps://orcid.org/0000-0003-3162-1849View further author information
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Antonis Kattamisd Professor of Pediatric Hematology-Oncology, Division of Pediatric Hematology-Oncology, First Department of Pediatrics, National and Kapodistrian University of Athens, Athens, GreeceORCID Iconhttps://orcid.org/0000-0002-5178-0655View further author information
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Thomas D Coatese Section Head, Hematology, Cancer and Blood Disease Institute, Professor of Pediatrics and Pathology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USAORCID Iconhttps://orcid.org/0000-0001-9878-6029View further author information
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Maciej Garbowskif Clinical Research Fellow, Department of Haematology, University College London Cancer Institute, London, UKORCID Iconhttps://orcid.org/0000-0001-6441-9562View further author information
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Franz Dürrenbergerg Head of Chemical and Preclinical R&D, Vifor (International) AG, Chemical and Preclinical Research and Development, St. Gallen, SwitzerlandView further author information
,
Vania Manolovah Head of Biology R&D, Vifor (International) AG, Chemical and Preclinical Research and Development, St. Gallen, SwitzerlandORCID Iconhttps://orcid.org/0000-0002-2072-8942View further author information
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Frank Richardi Clinical Research Director, Vifor Pharma AG, Glattbrugg, SwitzerlandORCID Iconhttps://orcid.org/0000-0003-1027-3814View further author information
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M. Domenica Cappellinij Professor of Internal Medicine, Department of Clinical Sciences and Community, University of Milan, Milan, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8676-6864View further author information
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Pages 633-644 | Received 06 Jan 2021, Accepted 25 May 2021, Published online: 29 Jul 2021

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François Rodrigues, Tereza Coman, Guillemette Fouquet, Francine Côté, Geneviève Courtois, Thiago Trovati Maciel & Olivier Hermine. (2023) A deep dive into future therapies for microcytic anemias and clinical considerations. Expert Review of Hematology 16:5, pages 349-364.
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Articles from other publishers (8)

Rayan Bou-Fakhredin, Kevin H.M. Kuo & Ali T. Taher. (2023) Emerging Therapies in β-Thalassemia. Hematology/Oncology Clinics of North America 37:2, pages 449-462.
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Tomas Ganz, Elizabeta Nemeth, Stefano Rivella, Paul Goldberg, Andrew R. Dibble, Michael L. McCaleb, Shuling Guo, Brett P. Monia & Terrance D. Barrett. (2023) TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis. Advances in Therapy 40:4, pages 1317-1333.
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Marta Ferraresi, Daniele Lello Panzieri, Simona Leoni, Maria Domenica Cappellini, Antonis Kattamis & Irene Motta. (2023) Therapeutic perspective for children and young adults living with thalassemia and sickle cell disease. European Journal of Pediatrics 182:6, pages 2509-2519.
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Hermann AM Mucke. (2023) Patent Highlights June–July 2022. Pharmaceutical Patent Analyst 12:1, pages 5-11.
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Filomena Longo & Antonio Piga. (2022) Does Hepcidin Tuning Have a Role among Emerging Treatments for Thalassemia?. Journal of Clinical Medicine 11:17, pages 5119.
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Tirthadipa Pradhan-Sundd, Gregory J. Kato & Enrico M. Novelli. (2022) Molecular mechanisms of hepatic dysfunction in sickle cell disease: lessons from Townes mouse model. American Journal of Physiology-Cell Physiology 323:2, pages C494-C504.
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Bo Liu, Tiantian Shi, Shaojiang Tian, Xianrui Luo, Chen Yang & Jing Wen. (2022) Efficacy and Mechanism of Roxadustat plus Oral Iron in the Treatment of Elderly Chronic Kidney Disease with Anemia. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-6.
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Antonis Kattamis, Janet L Kwiatkowski & Yesim Aydinok. (2022) Thalassaemia. The Lancet 399:10343, pages 2310-2324.
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