Advanced search
Publication Cover
Expert Review of Gastroenterology & Hepatology Volume 10, 2016 - Issue 9
Submit an article Journal homepage
921
Views
30
CrossRef citations to date
0
Altmetric
Review

Targeting endoplasmic reticulum stress in liver disease

Fa-Ling WuDepartment of Hepatology, Liver Research Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China;Institute of Hepatology, Wenzhou Medical University, Wenzhou, China
,
Wen-Yue LiuDepartment of Endocrinology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
,
Sven Van PouckeDepartment of Anesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, Ziekenhuis Oost-Limburg, Genk, Belgium
,
Martin BraddockGlobal Medicines Development, AstraZeneca R&D, Alderley Park, UK
,
Wei-Min JinDepartment of Infection Diseases, People Hospital of Wencheng County, Wenzhou, China
,
Jian XiaoInstitute of Biology Science, Wenzhou University, Wenzhou, China;School of Pharmacy, Wenzhou Medical University, Wenzhou, China
,
Xiao-Kun LiInstitute of Biology Science, Wenzhou University, Wenzhou, China;School of Pharmacy, Wenzhou Medical University, Wenzhou, ChinaCorrespondence[email protected]
&
Ming-Hua ZhengDepartment of Hepatology, Liver Research Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China;Institute of Hepatology, Wenzhou Medical University, Wenzhou, ChinaCorrespondence[email protected]
 show all
Pages 1041-1052 | Received 08 Jan 2016, Accepted 13 Apr 2016, Published online: 03 May 2016

Citations (30)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Liyue Zhou, Yifan Li, Qiangwei Liang, Jinxia Liu & Yanhua Liu. (2022) Combination therapy based on targeted nano drug co-delivery systems for liver fibrosis treatment: a review. Journal of Drug Targeting 30:6, pages 577-588.
Read now
Zhao-Qing Shen, Yi-Long Huang & Ting-Fen Tsai. (2018) Cisd2 haploinsufficiency: A driving force for hepatocellular carcinoma. Molecular & Cellular Oncology 5:3.
Read now

Articles from other publishers (28)

Xin Zhou, Yiwei Zeng, Runchen Zheng, Yuemei Wang, Tao Li, Shanshan Song, Su Zhang, Jinzhu Huang & Yulan Ren. (2023) Natural products modulate cell apoptosis: a promising way for treating endometrial cancer. Frontiers in Pharmacology 14.
Crossref
Jiaxin Li, Hengju Ge, Yang Xu, Jiahong Xie, Naymul Karim, Fujie Yan, Jianling Mo & Wei Chen. (2023) Chlorogenic acid alleviates oxidative damage in hepatocytes by regulating miR-199a-5p/GRP78 axis. Food Bioscience 53, pages 102595.
Crossref
Ling-Li Wang, Ya-Ru Zhang, Ming-Hua Zheng, Xuan Wang, Xue Wu & Jing-Yi Jin. (2023) A single fluorescent probe reveals changes in endoplasmic reticulum–mitochondria contact in hepatocytes during ferroptosis. Chemical Engineering Journal 466, pages 143104.
Crossref
Zhijie Yang, Chun Wang, Xia Zhang, Jing Li, Ziqi Zhang, Zhao Tan, Junyi Wang, Junyang Zhang & Xiaofeng Bai. (2022) Stem cells from human exfoliated deciduous teeth attenuate trigeminal neuralgia in rats by inhibiting endoplasmic reticulum stress. The Korean Journal of Pain 35:4, pages 383-390.
Crossref
Syamala Soumyakrishnan, Cheemachanahalli Muninanjappa Mohan Gowda, Shivanna Uma, Meghavarnam Anil Kumar, Sujatha Peela & Meenakshisundaram Sreepriya. 2022. Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma. Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma 219 242 .
Yichao Du, Furui Zhong, Huanli Cheng, Tongxi Li, Yifan Chen, Peng Tan, Meizhou Huang, Tiancheng Liang, Yu Liu, Xianming Xia & Wenguang Fu. (2021) The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome. Oxidative Medicine and Cellular Longevity 2021, pages 1-12.
Crossref
Lingjin Kong, Huiping Huang, Shaohua Luan, Hui Liu, Manping Ye & Fanrong Wu. (2021) Inhibition of ASIC1a-Mediated ERS Improves the Activation of HSCs and Copper Transport Under Copper Load. Frontiers in Pharmacology 12.
Crossref
Yazhou Guo, Chen Yang, Rong Guo, Ruijie Huang, Yongxia Su, Shuai Wang, Yezi Kong, Jianguo Wang, Chengjian Tan, Chonghui Mo, Chenchen Wu & Baoyu Zhao. (2021) CHOP Regulates Endoplasmic Reticulum Stress-Mediated Hepatoxicity Induced by Monocrotaline. Frontiers in Pharmacology 12.
Crossref
Huan Chen, Maoyuan Mu, Qichuan Liu, Han Hu, Caiyun Tian, Guoyuan Zhang, Ying Li, Fangwan Yang & Shide Lin. (2021) Hepatocyte Endoplasmic Reticulum Stress Inhibits Hepatitis B Virus Secretion and Delays Intracellular Hepatitis B Virus Clearance After Entecavir Treatment. Frontiers in Medicine 7.
Crossref
Ying Yang, Guiming Guo, Wei Zhou, Yunxuan Ge, Zheng Fan, Qingquan Liu & Yue Gao. (2021) Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells. Journal of Pharmacological Sciences 145:2, pages 175-186.
Crossref
Yaming Liu, Jessica L. Maiers, Yajuan Rui, Xiaoming Jiang, Bayasi Guleng & Jianlin Ren. (2021) Apolipoprotein H drives hepatitis B surface antigen retention and endoplasmic reticulum stress during hepatitis B virus infection. The International Journal of Biochemistry & Cell Biology 131, pages 105906.
Crossref
Anna Bogdańska, Patryk Lipiński, Paulina Szymańska-Rożek, Irena Jankowska, Piotr Socha & Anna Tylki-Szymańska. (2021) Pediatric Liver Disease Patients and Secondary Glycosylation Abnormalities. Frontiers in Pediatrics 8.
Crossref
Nur Banu Bal, Sevtap Han, Saba Kiremitci, Mecit Orhan Uludag & Emine Demirel-Yilmaz. (2020) Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress. Molecular Biology Reports 47:3, pages 2243-2252.
Crossref
Ningxun Cui, Mingling Cui, Jie Li, Xueping Zhu & Xiaoli Zhu. (2020) Suppression of IRE1 α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model . Gastroenterology Research and Practice 2020, pages 1-7.
Crossref
Sreelekshmi Mohan, Preetha Rani M. R, Lindsay Brown, Prathapan Ayyappan & Raghu K. G. (2019) Endoplasmic reticulum stress: A master regulator of metabolic syndrome. European Journal of Pharmacology 860, pages 172553.
Crossref
Congwen Wei, Xiaoli Yang, Ning Liu, Jin Geng, Yanhong Tai, Zhenyu Sun, Gangwu Mei, Pengyu Zhou, Yumeng Peng, Chenbin Wang, Xiaoli Zhang, Pingping Zhang, Yunqi Geng, Yujie Wang, Xiaotong Zhang, Xin Liu, Yanhong Zhang, Feixiang Wu, Xiang He & Hui Zhong. (2019) Tumor Microenvironment Regulation by the Endoplasmic Reticulum Stress Transmission Mediator Golgi Protein 73 in Mice. Hepatology 70:3, pages 851-870.
Crossref
Gaiping Wang, Liya Cheng, Meng Chen, Congcong Zhao, Mingxin Gao, Tiantian Huang, Peipei Chu & Cunshuan Xu. (2019) Comparative Analysis of Expression Profiles of Reg Signaling Pathways-Related Genes Between AHF and HCC. Biochemical Genetics 57:3, pages 382-402.
Crossref
Da Hyun Lee, Buhyun Lee, Jeong Su Park, Yu Seol Lee, Jin Hee Kim, Yejin Cho, Yoonjung Jo, Hyun-Seok Kim, Yong-ho Lee, Ki Taek Nam & Soo Han Bae. (2019) Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation. BMB Reports 52:3, pages 190-195.
Crossref
Inge Mannaerts, Lien F. R. Thoen, Nathalie Eysackers, Francisco Javier Cubero, Sofia Batista Leite, Iain Coldham, Isabelle Colle, Christian Trautwein & Leo A. van Grunsven. (2019) Unfolded protein response is an early, non-critical event during hepatic stellate cell activation. Cell Death & Disease 10:2.
Crossref
Tian-lu Shi, Lei Zhang, Qi-yao Cheng, Ji-shuang Yu, Jun Liu, Yu-jun Shen, Xiao-jun Feng & Yu-xian Shen. (2019) Xanthatin induces apoptosis by activating endoplasmic reticulum stress in hepatoma cells. European Journal of Pharmacology 843, pages 1-11.
Crossref
M Aslan, E Kıraç, Ö Yılmaz, B Ünal, EK Konuk, F Özcan & H Tuzcu. (2017) Effect of tauroursodeoxycholic acid on PUFA levels and inflammation in an animal and cell model of hepatic endoplasmic reticulum stress. Human & Experimental Toxicology 37:8, pages 803-816.
Crossref
Paul Lebeau, Khrystyna Platko, Ali A. Al-Hashimi, Jae Hyun Byun, Šárka Lhoták, Nicholas Holzapfel, Gabriel Gyulay, Suleiman A. Igdoura, David R. Cool, Bernardo Trigatti, Nabil G. Seidah & Richard C. Austin. (2018) Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. Journal of Biological Chemistry 293:19, pages 7329-7343.
Crossref
Ying Yang, Xianglin Tang, Feiran Hao, Zengchun Ma, Yuguang Wang, Lili Wang & Yue Gao. (2018) Bavachin Induces Apoptosis through Mitochondrial Regulated ER Stress Pathway in HepG2 Cells. Biological and Pharmaceutical Bulletin 41:2, pages 198-207.
Crossref
Romain Barnault, Thomas Lahlali, Marie-Laure Plissonnier, Cristina Romero-López, Noémie Laverdure, Benjamin Ducarouge, Michel Rivoire, Patrick Mehlen, Fabien Zoulim & Romain Parent. (2018) Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes. Biochemical and Biophysical Research Communications 495:4, pages 2425-2431.
Crossref
Theerut Luangmonkong, Su Suriguga, Henricus A. M. Mutsaers, Geny M. M. Groothuis, Peter Olinga & Miriam Boersema. 2018. Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175. Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175 71 102 .
Bin Feng, Xiaohua Huang, Dandan Jiang, Lun Hua, Yong Zhuo & De Wu. (2017) Endoplasmic Reticulum Stress Inducer Tunicamycin Alters Hepatic Energy Homeostasis in Mice. International Journal of Molecular Sciences 18:8, pages 1710.
Crossref
Michael Hinton, Yunzhou Li, Eric Kwong & Huiping Zhou. 2017. Cellular Injury in Liver Diseases. Cellular Injury in Liver Diseases 37 53 .
Suzanna HuppelschotenBob van de Water. (2016) Drug-Induced Liver Injury and TNFα Signaling: From In Vivo Understanding to In Vitro Testing Approaches . Applied In Vitro Toxicology 2:4, pages 197-206.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.