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Expert Review of Respiratory Medicine Volume 10, 2016 - Issue 6
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Review

Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches

Helena Lund-PalauDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UKView further author information
,
Andrew R. TurnbullDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK;Department of Respiratory Paediatrics, Royal Brompton and Harefield NHS Foundation Trust, London, UKCorrespondence[email protected]
View further author information
,
Andrew BushDepartment of Respiratory Paediatrics, Royal Brompton and Harefield NHS Foundation Trust, London, UK;National Heart and Lung Institute, Imperial College, London, UKView further author information
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Emmanuelle BardinBiomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, London, UKView further author information
,
Loren CameronDepartment of Medicine, Imperial College, London, UKView further author information
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Odel SorenBiological Sciences, Institute for Life Sciences, University of Southampton, Southampton, UKView further author information
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Natasha Wierre-GoreNational Heart and Lung Institute, Imperial College, London, UKView further author information
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Eric W. F. W. AltonDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UKView further author information
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Jacob G. BundyNational Heart and Lung Institute, Imperial College, London, UKView further author information
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Gary ConnettNIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, UKView further author information
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Saul N. FaustNIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, UKView further author information
,
Alain FillouxDepartment of Life Sciences, Imperial College, London, UKView further author information
,
Paul FreemontDepartment of Medicine, Imperial College, London, UKView further author information
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Andy JonesDepartment of Respiratory Medicine, Royal Brompton Hospital, London, UKView further author information
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Valerie KhooNational Heart and Lung Institute, Imperial College, London, UKView further author information
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Sandra MoralesAmpliPhi Australia, Sydney, AustraliaView further author information
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Ronan MurphyDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UKView further author information
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Rishi PabaryDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UKView further author information
,
Ameze SimboDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UKView further author information
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Silke SchelenzDepartment of Microbiology, Royal Brompton Hospital, LondonUKView further author information
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Zoltan TakatsBiomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, London, UKView further author information
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Jeremy WebbDepartment of Microbiology, Royal Brompton Hospital, LondonUKView further author information
,
Huw D. WilliamsNIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, UKView further author information
&
Jane C. DaviesDepartment of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK;Department of Respiratory Paediatrics, Royal Brompton and Harefield NHS Foundation Trust, London, UKView further author information
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Pages 685-697 | Received 13 Jan 2016, Accepted 08 Apr 2016, Published online: 13 May 2016

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Odete R. Mendes. 2023. Viral, Parasitic, Bacterial, and Fungal Infections. Viral, Parasitic, Bacterial, and Fungal Infections 591 608 .
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Crossref
Yuncheng Wang, Rachel Yoon Kyung Chang, Warwick J. Britton & Hak-Kim Chan. (2022) Advances in the development of antimicrobial peptides and proteins for inhaled therapy. Advanced Drug Delivery Reviews 180, pages 114066.
Crossref
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Pranita D Tamma, Stephan Beisken, Yehudit Bergman, Andreas E Posch, Edina Avdic, Sima L Sharara, Sara E Cosgrove & Patricia J Simner. (2021) Modifiable Risk Factors for the Emergence of Ceftolozane-tazobactam Resistance. Clinical Infectious Diseases 73:11, pages e4599-e4606.
Crossref
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Crossref
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Crossref
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Crossref
Catherine Enochs, Amy G. FilbrunCourtney IwanickiHaley MoraniecJulie LehrmannJourdan StifflerSharyn DagherChris TapleyHanna PhanRebekah RainesSamya Z. Nasr. (2021) Development of an Interdisciplinary Telehealth Care Model in a Pediatric Cystic Fibrosis Center. Telemedicine Reports 2:1, pages 224-232.
Crossref
Francois Lebreton, Erik Snesrud, Lindsey Hall, Emma Mills, Madeline Galac, Jason Stam, Ana Ong, Rosslyn Maybank, Yoon I Kwak, Sheila Johnson, Michael Julius, Melissa Ly, Brett Swierczewski, Paige E Waterman, Mary Hinkle, Anthony Jones, Emil Lesho, Jason W Bennett & Patrick McGann. (2021) A panel of diverse Pseudomonas aeruginosa clinical isolates for research and development . JAC-Antimicrobial Resistance 3:4.
Crossref
Bashudev Rudra & Radhey S. Gupta. (2021) Phylogenomic and comparative genomic analyses of species of the family Pseudomonadaceae: Proposals for the genera Halopseudomonas gen. nov. and Atopomonas gen. nov., merger of the genus Oblitimonas with the genus Thiopseudomonas, and transfer of some misclassified species of the genus Pseudomonas into other genera. International Journal of Systematic and Evolutionary Microbiology 71:9.
Crossref
Haitao Yang, Yan Wang, Qiankun Yang, Hui Fan, Lei Wang, Tianmeng Zhang, Zhixing Li, Gang Liu, Panpan Zhao, Huahua Wu, Jingquan Dong & Wei Liang. (2021) A Rapid and Sensitive Detection Method for Pseudomonas aeruginosa Using Visualized Recombinase Polymerase Amplification and Lateral Flow Strip Technology. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Myles B. Poulin & Laura L. Kuperman. (2021) Regulation of Biofilm Exopolysaccharide Production by Cyclic Di-Guanosine Monophosphate. Frontiers in Microbiology 12.
Crossref
J Stuart Elborn, Patrick A Flume, Donald R Van Devanter & Claudio Procaccianti. (2021) Management of chronic Pseudomonas aeruginosa infection with inhaled levofloxacin in people with cystic fibrosis . Future Microbiology 16:14, pages 1087-1104.
Crossref
Kumar Karki, Santosh Sigdel & Sunam Kafle. (2021) Is it Worth Adding Systemic Antibiotics to Inhalational Tobramycin Therapy to Treat Pseudomonas Infections in Cystic Fibrosis?. Cureus.
Crossref
Michal Shteinberg, Iram J Haq, Deepika Polineni & Jane C Davies. (2021) Cystic fibrosis. The Lancet 397:10290, pages 2195-2211.
Crossref
Gertrudis Horna & Joaquim Ruiz. (2021) Type 3 secretion system of Pseudomonas aeruginosa. Microbiological Research 246, pages 126719.
Crossref
Felix Behrens, Teresa C. Funk-Hilsdorf, Wolfgang M. Kuebler & Szandor Simmons. (2021) Bacterial Membrane Vesicles in Pneumonia: From Mediators of Virulence to Innovative Vaccine Candidates. International Journal of Molecular Sciences 22:8, pages 3858.
Crossref
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Crossref
Juliette L. Oakley, Rebecca Weiser, Lydia C. Powell, Julian Forton, Eshwar Mahenthiralingam, Philip D. Rye, Katja E. Hill, David W. Thomas & Manon F. Pritchard. (2021) Phenotypic and Genotypic Adaptations in Pseudomonas aeruginosa Biofilms following Long-Term Exposure to an Alginate Oligomer Therapy. mSphere 6:1.
Crossref
Sayantani Chatterjee, Rebeca Kawahara, Harry C. Tjondro, David R. Shaw, Marni A. Nenke, David J. Torpy & Morten Thaysen-Andersen. (2021) Serum N-Glycomics Stratifies Bacteremic Patients Infected with Different Pathogens. Journal of Clinical Medicine 10:3, pages 516.
Crossref
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Crossref
Alexander Seupt, Monika Schniederjans, Jürgen Tomasch & Susanne Häussler. (2020) Expression of the MexXY Aminoglycoside Efflux Pump and Presence of an Aminoglycoside-Modifying Enzyme in Clinical Pseudomonas aeruginosa Isolates Are Highly Correlated. Antimicrobial Agents and Chemotherapy 65:1.
Crossref
Michael Sörensen, Bakhodur Khakimov, Dennis Nurjadi, Sébastien Boutin, Buqing Yi, Alexander H. Dalpke & Tatjana Eigenbrod. (2020) Comparative evaluation of the effect of different growth media on in vitro sensitivity to azithromycin in multi-drug resistant Pseudomonas aeruginosa isolated from cystic fibrosis patients. Antimicrobial Resistance & Infection Control 9:1.
Crossref
Nashrawan Lababidi, Carlos Victor Montefusco-Pereira, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr & Marc Schneider. (2020) Spray-dried multidrug particles for pulmonary co-delivery of antibiotics with N-acetylcysteine and curcumin-loaded PLGA-nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 157, pages 200-210.
Crossref
Niamh E. Harrington, Esther Sweeney & Freya Harrison. (2020) Building a better biofilm - Formation of in vivo-like biofilm structures by Pseudomonas aeruginosa in a porcine model of cystic fibrosis lung infection. Biofilm 2, pages 100024.
Crossref
André M. Cantin, Cristine Ouellet, Alexandre Cloutier & Patrick P. McDonald. (2020) Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils. Frontiers in Pharmacology 11.
Crossref
Roser Ayats Vidal, Montserrat Bosque García, Miguel García González & Óscar Asensio de la Cruz. (2020) Infección bronquial por Pseudomonas aeruginosa en los pacientes con fibrosis quística diagnosticados por cribado neonatal. Archivos de Bronconeumología 56:8, pages 532-534.
Crossref
Roser Ayats Vidal, Montserrat Bosque García, Miguel García González & Óscar Asensio de la Cruz. (2020) Bronchial Infection due to Pseudomonas Aeruginosa in Patients with Cystic Fibrosis Diagnosed in Neonatal Screening. Archivos de Bronconeumología (English Edition) 56:8, pages 532-534.
Crossref
Tobias Depke, Janne Gesine Thöming, Adrian Kordes, Susanne Häussler & Mark Brönstrup. (2020) Untargeted LC-MS Metabolomics Differentiates Between Virulent and Avirulent Clinical Strains of Pseudomonas aeruginosa. Biomolecules 10:7, pages 1041.
Crossref
Nina Cramer, Sebastian Fischer, Silke Hedtfeld, Marie Dorda & Burkhard Tümmler. (2020) Intraclonal competitive fitness of longitudinal cystic fibrosis Pseudomonas aeruginosa airway isolates in liquid cultures . Environmental Microbiology 22:7, pages 2536-2549.
Crossref
David M. P. De Oliveira, Brian M. Forde, Timothy J. Kidd, Patrick N. A. Harris, Mark A. Schembri, Scott A. Beatson, David L. Paterson & Mark J. Walker. (2020) Antimicrobial Resistance in ESKAPE Pathogens. Clinical Microbiology Reviews 33:3.
Crossref
Ryan Thompson, Dominic Stephenson, Hannah E. Sykes, John D. Perry, Stephen P. Stanforth & John R. Dean. (2020) Detection of β-alanyl aminopeptidase as a biomarker for Pseudomonas aeruginosa in the sputum of patients with cystic fibrosis using exogenous volatile organic compound evolution . RSC Advances 10:18, pages 10634-10645.
Crossref
Onofrio Laselva, Tracy A. Stone, Christine E. Bear & Charles M. Deber. (2020) Anti-Infectives Restore ORKAMBI® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa. Biomolecules 10:2, pages 334.
Crossref
Ana F. Ramos, David F. Woods, Rachel Shanahan, Rafael Cano, Gerard P. McGlacken, Claudia Serra, Fergal O'Gara & F. Jerry Reen. (2020) A structure-function analysis of interspecies antagonism by the 2-heptyl-4-alkyl-quinolone signal molecule from Pseudomonas aeruginosa. Microbiology 166:2, pages 169-179.
Crossref
Odel Soren, Ardeshir Rineh, Diogo G Silva, Yuming Cai, Robert P Howlin, Raymond N Allan, Martin Feelisch, Jane C Davies, Gary J Connett, Saul N Faust, Michael J Kelso & Jeremy S Webb. (2020) Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 75:1, pages 117-125.
Crossref
Kosaku Komiya & Jun-Ichi Kadota. 2020. Aspiration Pneumonia. Aspiration Pneumonia 35 47 .
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R. Epaud, C. Delestrain, T.E. Weaver & H.T. Akinbi. (2019) Bacterial killing is enhanced by exogenous administration of lysozyme in the lungs. Respiratory Medicine and Research 76, pages 22-27.
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Crossref
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Crossref
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Crossref
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Tianhu Zhao, Jian Zhang, Maomao Tang, Luyan Z. Ma & Xiaoguang Lei. (2019) Development of an effective fluorescence probe for discovery of aminopeptidase inhibitors to suppress biofilm formation. The Journal of Antibiotics 72:6, pages 461-468.
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Crossref
Tiago Pita, Joana Feliciano & Jorge Leitão. (2018) Small Noncoding Regulatory RNAs from Pseudomonas aeruginosa and Burkholderia cepacia Complex. International Journal of Molecular Sciences 19:12, pages 3759.
Crossref
Francesca D'Angelo, Valerio Baldelli, Nigel Halliday, Paolo Pantalone, Fabio Polticelli, Ersilia Fiscarelli, Paul Williams, Paolo Visca, Livia Leoni & Giordano Rampioni. (2018) Identification of FDA-Approved Drugs as Antivirulence Agents Targeting the pqs Quorum-Sensing System of Pseudomonas aeruginosa . Antimicrobial Agents and Chemotherapy 62:11.
Crossref
Thibaud Boulant, Yves-Marie Boudehen, Alain Filloux, Patrick Plesiat, Thierry Naas & Laurent Dortet. (2018) Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains. Frontiers in Microbiology 9.
Crossref
Milton Aguilera, Laura Delgui, Patricia Romano & María Colombo. (2018) Chronic Infections: A Possible Scenario for Autophagy and Senescence Cross-Talk. Cells 7:10, pages 162.
Crossref
Trevor Beaudoin, Tracy A. Stone, Miroslawa Glibowicka, Christina Adams, Yvonne Yau, Saumel Ahmadi, Christine E. Bear, Hartmut Grasemann, Valerie Waters & Charles M. Deber. (2018) Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms. Scientific Reports 8:1.
Crossref
Jens Klockgether, Nina Cramer, Sebastian Fischer, Lutz Wiehlmann & Burkhard Tümmler. (2018) Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis Lungs . American Journal of Respiratory Cell and Molecular Biology 59:2, pages 246-256.
Crossref
Emmanuelle E. Bardin, Simon J. S. Cameron, Alvaro Perdones-Montero, Kate Hardiman, Frances Bolt, Eric W. F. W. Alton, Andrew Bush, Jane C. Davies & Zoltan Takáts. (2018) Metabolic Phenotyping and Strain Characterisation of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients Using Rapid Evaporative Ionisation Mass Spectrometry. Scientific Reports 8:1.
Crossref
S. Caskey, J. Stirling, J.E. Moore & J.C. Rendall. (2018) Occurrence of Pseudomonas aeruginosa in waters: implications for patients with cystic fibrosis (CF) . Letters in Applied Microbiology 66:6, pages 537-541.
Crossref
Laurent Dortet, Charlotte Lombardi, François Cretin, Andréa Dessen & Alain Filloux. (2018) Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome. Nature Microbiology 3:3, pages 378-386.
Crossref
Martina Valentini, Diego Gonzalez, Despoina AI Mavridou & Alain Filloux. (2018) Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa. Current Opinion in Microbiology 41, pages 15-20.
Crossref
Hunter J. Sismaet, Ameet J. Pinto & Edgar D. Goluch. (2017) Electrochemical sensors for identifying pyocyanin production in clinical Pseudomonas aeruginosa isolates. Biosensors and Bioelectronics 97, pages 65-69.
Crossref
Anna P. Soavelomandroso, Françoise Gaudin, Sandra Hoys, Valérie Nicolas, Gayatri Vedantam, Claire Janoir & Sylvie Bouttier. (2017) Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection. Frontiers in Microbiology 8.
Crossref
S. Stefani, S. Campana, L. Cariani, V. Carnovale, C. Colombo, M.M. Lleo, V.D. Iula, L. Minicucci, P. Morelli, G. Pizzamiglio & G. Taccetti. (2017) Relevance of multidrug-resistant Pseudomonas aeruginosa infections in cystic fibrosis. International Journal of Medical Microbiology 307:6, pages 353-362.
Crossref
N. A. Mikhaylova, E. O. Kalinichenko, A. V. Soldatenkova & N. K. Akhmatova. (2017) RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA: EFFECT ON IMMUNE RESPONSE IN MICE. Journal of microbiology, epidemiology and immunobiology 94:3, pages 52-58.
Crossref
Sebastian Fischer, Leonie Greipel, Jens Klockgether, Marie Dorda, Lutz Wiehlmann, Nina Cramer & Burkhard Tümmler. (2017) Multilocus amplicon sequencing of Pseudomonas aeruginosa cystic fibrosis airways isolates collected prior to and after early antipseudomonal chemotherapy. Journal of Cystic Fibrosis 16:3, pages 346-352.
Crossref
Nyakaat Ninyio Nathaniel, Bashir Gidado Hadiza, O. Yahaya Mariama, Tayaza, A. Bamanga Raji & M. Yaki Lucy. (2017) Ethanolic Allium sativum extract down-regulates the pelF gene involved in Pseudomonas aeruginosa biofilm formation. African Journal of Biotechnology 16:12, pages 585-593.
Crossref
Isabelle Fajac & Kris De Boeck. (2017) New horizons for cystic fibrosis treatment. Pharmacology & Therapeutics 170, pages 205-211.
Crossref

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