3,652
Views
31
CrossRef citations to date
0
Altmetric
Review

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

, , &
Pages 301-324 | Received 31 Aug 2020, Accepted 05 Nov 2020, Published online: 26 Nov 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Mohammad A. Uddin, Mohammad S. Akhter, Khadeja-Tul Kubra & Nektarios Barabutis. (2021) Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis. Tissue Barriers 9:4.
Read now

Articles from other publishers (30)

Shi Ying, Yu Chaoping, Yu Zhuoyang, Shang Jin, Yang Qinyan, Liang Yuxin, Lai Chunyou, Feng Tianhang, Yao Yutong, Zeng Fan, Huang Xiaolun, Liu Tianhu, Liu Xiaowei, Xinchen Zhao & Luoyi Chen. 2024. Recent Update on Mesenchymal Stem Cells [Working Title]. Recent Update on Mesenchymal Stem Cells [Working Title].
Christian Bode, Sebastian Weis, Andrea Sauer, Pedro Wendel-Garcia & Sascha David. (2023) Targeting the host response in sepsis: current approaches and future evidence. Critical Care 27:1.
Crossref
Mehrdad Moosazadeh Moghaddam, Parvindokht Fazel, Arezoo Fallah, Hamid Sedighian, Reza Kachuei, Elham Behzadi & Abbas Ali Imani Fooladi. (2023) Host and Pathogen-Directed Therapies against Microbial Infections Using Exosome- and Antimicrobial Peptide-derived Stem Cells with a Special look at Pulmonary Infections and Sepsis. Stem Cell Reviews and Reports 19:7, pages 2166-2191.
Crossref
Cécile Pochon, Caroline Laroye, Antoine Kimmoun, Loic Reppel, Adéle Dhuyser, Hélène Rousseau, Mélanie Gauthier, Nadine Petitpain, Jean-François Chabot, Simon Valentin, Marcelo de Carvalho Bittencourt, Michael Peres, Alice Aarnink, Véronique Decot, Danièle Bensoussan & Sébastien Gibot. (2023) Efficacy of Wharton Jelly Mesenchymal Stromal Cells infusions in moderate to severe SARS-Cov-2 related acute respiratory distress syndrome: a phase 2a double-blind randomized controlled trial. Frontiers in Medicine 10.
Crossref
Xiaoli Zhuang, Yu Jiang, Xiaofang Yang, Lin Fu, Lan Luo, Ziyuan Dong, Ju Zhao & Feilong Hei. (2023) Advances of mesenchymal stem cells and their derived extracellular vesicles as a promising therapy for acute respiratory distress syndrome: from bench to clinic. Frontiers in Immunology 14.
Crossref
Ellen A. Gorman, Jennifer Rynne, Hannah J. GardinerAnthony J. Rostron, Jonathan Bannard-Smith, Andrew M. Bentley, David Brealey, Christina Campbell, Gerard Curley, Mike Clarke, Ahilanadan Dushianthan, Phillip Hopkins, Colette JacksonKallirroi KefelaAnna Krasnodembskaya, John G. Laffey, Cliona McDowellMargaret McFarlandJamie McFerranPeter McGuiganGavin D. Perkins, Jonathan Silversides, Jon SmytheJacqui ThompsonWilliam S. TunnicliffeIngeborg D.M. Welters, Laura Amado-Rodríguez, Guillermo Albaiceta, Barry Williams, Manu Shankar-Hari, Daniel F. McAuley & Cecilia M. O’Kane. (2023) Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicenter, Randomized, Controlled Clinical Trial. American Journal of Respiratory and Critical Care Medicine 208:3, pages 256-269.
Crossref
Declan Byrnes, Claire Masterson, Jack Brady, Shahd Horie, Sean D. McCarthy, Hector Gonzalez, Daniel O’Toole & John Laffey. (2023) Delayed MSC therapy enhances resolution of organized pneumonia induced by antibiotic resistant Klebsiella pneumoniae infection. Frontiers in Medicine 10.
Crossref
Yue Su, Johnatas Dutra Silva, Declan Doherty, David A Simpson, Daniel J Weiss, Sara Rolandsson-Enes, Daniel F McAuley, Cecilia M O'Kane, Derek P Brazil & Anna D Krasnodembskaya. (2023) Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis. Thorax 78:6, pages 617-630.
Crossref
Sabrina Mattoli & Matthias Schmidt. (2023) Investigational Use of Mesenchymal Stem/Stromal Cells and Their Secretome as Add-On Therapy in Severe Respiratory Virus Infections: Challenges and Perspectives. Advances in Therapy 40:6, pages 2626-2692.
Crossref
Tian-Yu Liang, Li-Hai Lu, Si-Yu Tang, Zi-Hao Zheng, Kai Shi & Jing-Quan Liu. (2023) Current status and prospects of basic research and clinical application of mesenchymal stem cells in acute respiratory distress syndrome. World Journal of Stem Cells 15:4, pages 150-164.
Crossref
Chih-Wei Zeng. (2023) Multipotent Mesenchymal Stem Cell-Based Therapies for Spinal Cord Injury: Current Progress and Future Prospects. Biology 12:5, pages 653.
Crossref
Tomasz Wojciech Rutkowski, Jerzy Jaroszewicz, Damian Piotrowski, Krzysztof Ślosarek, Barbara Sobala-Szczygieł, Dorota Słonina, Bożena Włostowska, Dawid Bodusz, Maciej Piasecki, Michał Nachlik, Barbara Oczko-Grzesik, Adam Gądek, Dorota Kowal, Roman Rutkowski, Elżbieta Wojarska-Tręda & Krzysztof Składowski. (2023) Low-Dose Radiotherapy for Patients with Pneumonia Due to COVID-19: A Single-Institution Prospective Study. Biomedicines 11:3, pages 858.
Crossref
Yaxin Li, Ziyang Wei, Xinyu Ma, Jing Xu, Xia Zhao, Qilong Cao & Guohu Di. (2023) Efficacy and Safety of Mesenchymal Stromal Cells Therapy for COVID-19 Infection: A Systematic Review and Meta-analysis. Current Stem Cell Research & Therapy 18:1, pages 143-152.
Crossref
Elliott T. Worku, Katrina Ki & Kiran Shekar. 2023. Cardiopulmonary Bypass. Cardiopulmonary Bypass 1003 1020 .
Maziar Malekzadeh Kebria, Peiman Brouki Milan, Noshad Peyravian, Jafar Kiani, Soheil Khatibi & Masoud Mozafari. (2022) Stem cell therapy for COVID-19 pneumonia. Molecular Biomedicine 3:1.
Crossref
Ellen Gorman, Manu Shankar-Hari, Phil Hopkins, William S. Tunnicliffe, Gavin D. Perkins, Jonathan Silversides, Peter McGuigan, Colette Jackson, Roisin Boyle, Jamie McFerran, Cliona McDowell, Christina Campbell, Margaret McFarland, Jon Smythe, Jacqui Thompson, Barry Williams, Gerard Curley, John G. Laffey, Mike Clarke, Daniel F. McAuley & Cecilia O’Kane. (2022) Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a randomised, triple-blind, allocation concealed, placebo-controlled phase 2 trial. Trials 23:1.
Crossref
Francesca Paris, Valeria Pizzuti, Pasquale Marrazzo, Andrea Pession, Francesco Alviano & Laura Bonsi. (2022) Perinatal Stem Cell Therapy to Treat Type 1 Diabetes Mellitus: A Never-Say-Die Story of Differentiation and Immunomodulation. International Journal of Molecular Sciences 23:23, pages 14597.
Crossref
Ellen A Gorman, Cecilia M O’Kane & Daniel F McAuley. (2022) Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management. The Lancet 400:10358, pages 1157-1170.
Crossref
Xiaoran Zhang, Xuxia Wei, Yiwen Deng, Xiaofeng Yuan, Jiahao Shi, Weijun Huang, Jing Huang, Xiaoyong Chen, Shuwei Zheng, Jieying Chen, Keyu Chen, Ruiming Xu, Hongmiao Wang, Weiqiang Li, Shiyue Li, Huimin Yi & Andy Peng Xiang. (2022) Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway. Signal Transduction and Targeted Therapy 7:1.
Crossref
Chao Cao, Lin Zhang, Fuli Liu & Jie Shen. (2022) Therapeutic Benefits of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome: Potential Mechanisms and Challenges. Journal of Inflammation Research Volume 15, pages 5235-5246.
Crossref
Marselina Irasonia Tan, Nayla Majeda Alfarafisa, Popi Septiani, Anggraini Barlian, Mochamad Firmansyah, Ahmad Faizal, Lili Melani & Husna Nugrahapraja. (2022) Potential Cell-Based and Cell-Free Therapy for Patients with COVID-19. Cells 11:15, pages 2319.
Crossref
Aidan M Kirkham, Adrian J M Bailey, Madeline Monaghan, Risa Shorr, Manoj M Lalu, Dean A Fergusson & David S Allan. (2022) Updated Living Systematic Review and Meta-analysis of Controlled Trials of Mesenchymal Stromal Cells to Treat COVID-19: A Framework for Accelerated Synthesis of Trial Evidence for Rapid Approval—FASTER Approval. Stem Cells Translational Medicine 11:7, pages 675-687.
Crossref
Nihal Karakaş, Süleyman Üçüncüoğlu, Damla Uludağ, Birnur Sinem Karaoğlan, Khalid Shah & Gürkan Öztürk. (2022) Mesenchymal Stem Cell-Based COVID-19 Therapy: Bioengineering Perspectives. Cells 11:3, pages 465.
Crossref
S.R. Aravind, Krupa Ann Mathew, Bernadette K. Madathil, S. Mini & Annie John. 2022. Stem Cells and COVID-19. Stem Cells and COVID-19 169 227 .
C. H. Masterson, A. Ceccato, A. Artigas, C. dos Santos, P. R. Rocco, S. Rolandsson Enes, D. J. Weiss, D. McAuley, M. A. Matthay, K. English, G. F. Curley & J. G. Laffey. (2021) Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challenges. Intensive Care Medicine Experimental 9:1.
Crossref
Timothy D. Shaw, Anna D. Krasnodembskaya, Gunnar N. Schroeder, Alimuddin Zumla, Markus Maeurer & Cecilia M. O’Kane. (2021) Mesenchymal Stromal Cells: an Antimicrobial and Host-Directed Therapy for Complex Infectious Diseases. Clinical Microbiology Reviews 34:4.
Crossref
Virginia Newcombe, Timothy Coats, Paul Dark, Anthony Gordon, Steve Harris, Danny F McAuley, David K Menon, Susanna Price, Zudin Puthucheary & Mervyn Singer. (2021) The future of acute and emergency care. Future Healthcare Journal 8:2, pages e230-e236.
Crossref
Panagiotis Mallis, Efstathios Michalopoulos, Theofanis Chatzistamatiou & Catherine Stavropoulos Giokas. (2021) Interplay between mesenchymal stromal cells and immune system: clinical applications in immune-related diseases. Exploration of Immunology.
Crossref
Birbal Singh, Gorakh Mal, Vinod Verma, Ruchi Tiwari, Muhammad Imran Khan, Ranjan K. Mohapatra, Saikat Mitra, Salem A. Alyami, Talha Bin Emran, Kuldeep Dhama & Mohammad Ali Moni. (2021) Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era. Stem Cell Research & Therapy 12:1.
Crossref
Huei-Yu Lo, Shun-Ping Cheng, Jing-Long Huang, Kuo-Ting Chang, Yu-Lung Chang, Chien-Hsun Huang, Chia-Jen Chang, Chien-Hua Chiu, Yui Whei Chen-Yang & Chin-Kan Chan. (2021) High Induction of IL-6 Secretion From hUCMSCs Optimize the Potential of hUCMSCs and TCZ as Therapy for COVID-19-Related ARDS. Cell Transplantation 30, pages 096368972110544.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.