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Review

Treatment strategies for DNA repair-deficient prostate cancer

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Pages 889-898 | Received 23 Mar 2017, Accepted 31 May 2017, Published online: 12 Jun 2017

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Adel Mandl, Mark C. Markowski, Michael A. Carducci & Emmanuel S. Antonarakis. (2023) Role of bromodomain and extraterminal (BET) proteins in prostate cancer. Expert Opinion on Investigational Drugs 32:3, pages 213-228.
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Eric S. Christenson & Emmanuel S. Antonarakis. (2018) PARP inhibitors for homologous recombination-deficient prostate cancer. Expert Opinion on Emerging Drugs 23:2, pages 123-133.
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Mark C. Markowski, Angelo M. De Marzo & Emmanuel S. Antonarakis. (2017) BET inhibitors in metastatic prostate cancer: therapeutic implications and rational drug combinations. Expert Opinion on Investigational Drugs 26:12, pages 1391-1397.
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Xianzhe Yu, Lingling Zhu, Ting Wang, Lu Li, Jiewei Liu, Guowei Che & Qinghua Zhou. (2023) Enhancing the anti-tumor response by combining DNA damage repair inhibitors in the treatment of solid tumors. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:4, pages 188910.
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Ramy Sedhom & Emmanuel S Antonarakis. (2019) Clinical implications of mismatch repair deficiency in prostate cancer. Future Oncology 15:20, pages 2395-2411.
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Catherine Handy Marshall, Wei Fu, Hao Wang, Alexander S. Baras, Tamara L. Lotan & Emmanuel S. Antonarakis. (2018) Prevalence of DNA repair gene mutations in localized prostate cancer according to clinical and pathologic features: association of Gleason score and tumor stage. Prostate Cancer and Prostatic Diseases 22:1, pages 59-65.
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Pasquale Rescigno, Robert Chandler & Johann de Bono. (2018) Relevance of poly (ADP-ribose) polymerase inhibitors in prostate cancer. Current Opinion in Supportive & Palliative Care 12:3, pages 339-343.
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Emmanuel S. Antonarakis, Changxue Lu, Brandon Luber, Chao Liang, Hao Wang, Yan Chen, John L. Silberstein, Danilo Piana, Zhao Lai, Yidong Chen, William B. Isaacs & Jun Luo. (2018) Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide. European Urology 74:2, pages 218-225.
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Emmanuel S Antonarakis. (2018) Abiraterone plus olaparib in prostate cancer: a new form of synthetic lethality?. The Lancet Oncology 19:7, pages 860-861.
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Karim Boudadi, Daniel L. Suzman, Valsamo Anagnostou, Wei Fu, Brandon Luber, Hao Wang, Noushin Niknafs, James R. White, John L. Silberstein, Rana Sullivan, Donna Dowling, Rana Harb, Thomas R. Nirschl, Brendan A. Veeneman, Scott A. Tomlins, Yipeng Wang, Adam Jendrisak, Ryon P. Graf, Ryan Dittamore, Michael A. Carducci, Mario A. Eisenberger, Michael C. Haffner, Alan K. Meeker, James R. Eshleman, Jun Luo, Victor E. Velculescu, Charles G. Drake & Emmanuel S. Antonarakis. (2018) Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer. Oncotarget 9:47, pages 28561-28571.
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George J. Netto, Marie-Lisa Eich & Sooryanarayana Varambally. (2017) Prostate Cancer: An Update on Molecular Pathology with Clinical Implications. European Urology Supplements 16:12, pages 253-271.
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