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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 73, 2018 - Issue 2
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Original Paper

Two years follow-up of an open-label pilot study of treatment with rituximab in patients with early diffuse cutaneous systemic sclerosis

Karin MelsensDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium;Faculty of Medicine and Health Sciences, Department of Internal Medicine, Universiteit Gent, Ghent, BelgiumCorrespondence[email protected]
,
Els VandecasteeleDepartment of Cardiology, Universitair Ziekenhuis Gent, Ghent, Belgium
,
Ellen DeschepperDepartment of Public Health, Biostatistics Unit, Universiteit Gent, Ghent, Belgium
,
Valérie BadotDepartment of Rheumatology, Hopital Erasme, Université Libre de Bruxelles, Brussels, Belgium
,
Daniel BlockmansDepartment of General Internal Medicine, universitaire ziekenhuizen leuven, Leuven, BelgiumORCID Iconhttp://orcid.org/0000-0001-9783-1780
ORCID Icon,
Guy BrusselleDepartment of Respiratory Medicine, Universitair Ziekenhuis Gent, Ghent, Belgium
,
Ellen De LangheDepartment of Rheumatology, universitaire ziekenhuizen leuven, Leuven, Belgium
,
Michel De PauwDepartment of Cardiology, Universitair Ziekenhuis Gent, Ghent, Belgium
,
Claire DebusschereDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium;Faculty of Medicine and Health Sciences, Department of Internal Medicine, Universiteit Gent, Ghent, Belgium
,
Saskia DecumanFaculty of Medicine and Health Sciences, Department of Internal Medicine, Universiteit Gent, Ghent, Belgium
,
Liselotte DerooFaculty of Medicine and Health Sciences, Universiteit Gent, Ghent, Belgium
,
Frédéric HoussiauDepartment of Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
,
Jan LenaertsDepartment of Rheumatology, universitaire ziekenhuizen leuven, Leuven, Belgium
,
Yves PietteDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium
,
Kristof ThevissenDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium
,
Marie VanthuyneDepartment of Rheumatology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
,
René WesthovensDepartment of Rheumatology, universitaire ziekenhuizen leuven, Leuven, Belgium
,
Sara WijnantFaculty of Medicine and Health Sciences, Universiteit Gent, Ghent, Belgium
,
Filip De KeyserDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium;Faculty of Medicine and Health Sciences, Department of Internal Medicine, Universiteit Gent, Ghent, Belgium
&
Vanessa SmithDepartment of Rheumatology, Universitair Ziekenhuis Gent, Ghent, Belgium;Faculty of Medicine and Health Sciences, Department of Internal Medicine, Universiteit Gent, Ghent, Belgium
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Pages 119-125 | Published online: 11 Sep 2017

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Esther F. Vicente-Rabaneda, José M. Serra López-Matencio, Julio Ancochea, Ricardo Blanco, Miguel Á. González-Gay & Santos Castañeda. (2022) Efficacy and safety of biological drugs in interstitial lung disease associated with connective tissue diseases. Expert Opinion on Drug Safety 21:3, pages 311-333.
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Nathalie Berghen, Jean-Baptiste Vulsteke, Rene Westhovens, Jan Lenaerts & Ellen De Langhe. (2019) Rituximab in systemic autoimmune rheumatic diseases: indications and practical use. Acta Clinica Belgica 74:4, pages 272-279.
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Articles from other publishers (23)

Marina Maria Vieira de Figueiredo Caldas, Kesley Pablo Morais de Azevedo, Ana Clara de França Nunes, Victor Hugo de Oliveira, Isac Davidson Santiago Fernandes Pimenta, Isabela Dantas Torres de Araújo, Francisco Alves Bezerra Neto, Ana Katherine da Silveira Gonçalves de Oliveira & Grasiela Piuvezam. (2021) Is rituximab effective for systemic sclerosis? A systematic review and meta-analysis. Advances in Rheumatology 61:1.
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Giacomo De Luca, Alessandro Tomelleri, Lorenzo Dagna & Marco Matucci-Cerinic. (2021) The target on B cells in Systemic Sclerosis: a “midsummer dream” to extinguish inflammation and prevent early disease progression to fibrosis. Clinical Rheumatology 40:7, pages 2529-2533.
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Konstantinos Melissaropoulos & Dimitrios Daoussis. (2021) B cells in systemic sclerosis: from pathophysiology to treatment. Clinical Rheumatology 40:7, pages 2621-2631.
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Sasimon Borrirukwisitsak, Pongchirat Tantayakom & Wanrachada Katchamart. (2021) Efficacy and safety of rituximab on lung and skin involvement in systemic sclerosis: a systematic review and metaanalysis. Clinical Rheumatology 40:7, pages 2779-2789.
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Gilda Sandri, Carlo Umberto Manzini & Carlo Salvarani. (2021) On- and off-label use of rituximab in rheumatic diseases. Beyond Rheumatology 3:1.
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Maliheh Moradzadeh, Mehrdad Aghaei, Zahra Mehrbakhsh, Zahra Arab-Bafrani & Nafiseh Abdollahi. (2021) Efficacy and safety of rituximab therapy in patients with systemic sclerosis disease (SSc): systematic review and meta-analysis. Clinical Rheumatology.
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Georges Jalkh, Rachelle Abi Nahed, Gabrielle Macaron & Mary Rensel. (2020) Safety of Newer Disease Modifying Therapies in Multiple Sclerosis. Vaccines 9:1, pages 12.
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Julián E. Barahona-Correa, Alejandro De la Hoz, María José López, Javier Garzón, Yannick Allanore & Gerardo Quintana-López. (2020) Infecciones y esclerosis sistémica: un desafío emergente. Revista Colombiana de Reumatología 27, pages 62-84.
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Javier Narváez, Judit LLuch, Maria Molina-Molina, Vanesa Vicens-Zygmunt, Patricio Luburich, Marcos Anibal Yañez & Joan M. Nolla. (2020) Rituximab as a rescue treatment added on mycophenolate mofetil background therapy in progressive systemic sclerosis associated interstitial lung disease unresponsive to conventional immunosuppression. Seminars in Arthritis and Rheumatism 50:5, pages 977-987.
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Belén Atienza-Mateo, Sara Remuzgo-Martínez, Diana Prieto-Peña, Víctor Manuel Mora Cuesta, David Iturbe-Fernández, Javier Llorca, Lara Sánchez-Bilbao, Alfonso Corrales, Gerardo Blanco Rodríguez, José Javier Gómez-Román, José Manuel Cifrián & Miguel Ángel González-Gay. (2020) Rituximab in the Treatment of Interstitial Lung Disease Associated with Autoimmune Diseases: Experience from a Single Referral Center and Literature Review. Journal of Clinical Medicine 9:10, pages 3070.
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L. P. Ananieva, L. A. Garzanova, O. V. Desinova, O. A. Koneva, M. N. Starovoytova, O. B. Ovsyannikova, A. P. Aleksankn & S. I. Glukhova. (2020) Short-term absolute B-cell counts monitoring in systemic sclerosis patients treated with rituximab. Rheumatology Science and Practice 58:4, pages 395-400.
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Robert W. Simms. (2020) Expert Perspectives On Clinical Challenges: Expert Perspectives: Challenges in Scleroderma. Arthritis & Rheumatology 72:9, pages 1415-1426.
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Tatiana Nevskaya, Boyang Zheng, Carl A Baxter, Dena R Ramey, Janet E Pope & Murray Baron. (2020) Skin improvement is a surrogate for favourable changes in other organ systems in early diffuse cutaneous systemic sclerosis. Rheumatology 59:7, pages 1715-1724.
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Rui Tang, Jiangfan Yu, Yaqian Shi, Puyu Zou, Zhuotong Zeng, Bingsi Tang, Yaoyao Wang, Guanghui Ling, Mei Luo & Rong Xiao. (2020) Safety and efficacy of Rituximab in systemic sclerosis: A systematic review and meta-analysis. International Immunopharmacology 83, pages 106389.
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Durga Prasanna Misra, Sakir Ahmed & Vikas Agarwal. (2020) Is biological therapy in systemic sclerosis the answer?. Rheumatology International 40:5, pages 679-694.
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Julián E. Barahona-Correa, Alejandro De la Hoz, María José López, Javier Garzón, Yannick Allanore & Gerardo Quintana-López. (2020) Infections and systemic sclerosis: an emerging challenge. Revista Colombiana de Reumatología (English Edition) 27, pages 62-84.
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Boyang Zheng, Tatiana Nevskaya, Carl A Baxter, Dena R Ramey, Janet E Pope, Murray Baron, Janet E Pope, Murray Baron, Marie Hudson, Geneviève Gyger, Maggie J Larché, Nader A Khalidi, Ariel Masetto, Evelyn Sutton, David Robinson, Tatiana S Rodriguez-Reyna, Doug Smith, Carter Thorne, Paul R Fortin, Marvin J Fritzler, Janet E Pope, Murray Baron, Marie Hudson, Geneviève Gyger, Maggie J Larché, Nader A Khalidi, Ariel Masetto, Evelyn Sutton, David Robinson, Tatiana S Rodriguez-Reyna, Doug Smith, Carter Thorne, Paul R Fortin & Marvin J Fritzler. (2020) Changes in skin score in early diffuse cutaneous systemic sclerosis are associated with changes in global disease severity. Rheumatology 59:2, pages 398-406.
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Mattia Bellan, Filippo Patrucco, Francesco Barone-Adesi, Francesco Gavelli, Luigi Mario Castello, Alessandra Nerviani, Laura Andreoli, Lorenzo Cavagna, Mario Pirisi & Pier Paolo Sainaghi. (2020) Targeting CD20 in the treatment of interstitial lung diseases related to connective tissue diseases: A systematic review. Autoimmunity Reviews 19:2, pages 102453.
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Konstantinos Melissaropoulos, Pantelis Kraniotis, Dimitrios Bogdanos, Theodoros Dimitroulas, Lazaros Sakkas & Dimitrios Daoussis. (2019) Targeting very early systemic sclerosis: a case-based review. Rheumatology International 39:11, pages 1961-1970.
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Muriel Elhai, Marouane Boubaya, Oliver Distler, Vanessa Smith, Marco Matucci-Cerinic, Juan José Alegre Sancho, Marie-Elise Truchetet, Yolanda Braun-Moscovici, Florenzo Iannone, Pavel I Novikov, Alain Lescoat, Elise Siegert, Ivan Castellví, Paolo Airó, Serena Vettori, Ellen De Langhe, Eric Hachulla, Anne Erler, Lidia Ananieva, Martin Krusche, F J López-Longo, Jörg H W Distler, Nicolas Hunzelmann, Anna-Maria Hoffmann-Vold, Valeria Riccieri, Vivien M Hsu, Maria R Pozzi, Codrina Ancuta, Edoardo Rosato, Carina Mihai, Masataka Kuwana, Lesley Ann Saketkoo, Carlo Chizzolini, Roger Hesselstrand, Susanne Ullman, Sule Yavuz, Simona Rednic, Cristian Caimmi, Coralie Bloch-Queyrat & Yannick Allanore. (2019) Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study. Annals of the Rheumatic Diseases 78:7, pages 979-987.
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Marina Maria Vieira de Figueiredo Caldas, Francisco Alves Bezerra Neto, Kesley Pablo Morais de Azevedo, Isac Davidson Santiago Fernandes Pimenta, Ana Katherine Da Silveira Gonçalves De Oliveira & Grasiela Piuvezam. (2019) Rituximab in systemic sclerosis. Medicine 98:38, pages e17110.
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Chi Liu, Xue Yang, Ping Zhu, Masayuki Fujino, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Jiucun Wang, Jian Zhuang, Hejian Zou & Xiao-Kang Li. (2018) Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine sclerodermatous graft-versus-host disease. Experimental Dermatology 27:10, pages 1104-1111.
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Mathilde Thiebaut, David Launay, Sébastien Rivière, Thibault Mahévas, Syrine Bellakhal, Eric Hachulla, Olivier Fain & Arsène Mekinian. (2018) Efficacy and safety of rituximab in systemic sclerosis: French retrospective study and literature review. Autoimmunity Reviews 17:6, pages 582-587.
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