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Cell Adhesion & Migration Volume 12, 2018 - Issue 6: Kinases in Cancer
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Commentary - Solicited

Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion

Adelaide IJ YoungCancer Research Division, Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, AustraliaORCID Iconhttp://orcid.org/0000-0002-5714-0501View further author information
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Paul TimpsonCancer Research Division, Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, Australia;St. Vincent's Clinical School, UNSW Medicine, Victoria Street, Darlinghurst, NSW, AustraliaORCID Iconhttp://orcid.org/0000-0002-5514-7080View further author information
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David Gallego-OrtegaCancer Research Division, Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, Australia;St. Vincent's Clinical School, UNSW Medicine, Victoria Street, Darlinghurst, NSW, AustraliaORCID Iconhttp://orcid.org/0000-0002-2347-7835View further author information
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Christopher J. OrmandyCancer Research Division, Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, Australia;St. Vincent's Clinical School, UNSW Medicine, Victoria Street, Darlinghurst, NSW, AustraliaORCID Iconhttp://orcid.org/0000-0002-2504-7919View further author information
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Samantha R. OakesCancer Research Division, Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, Australia;St. Vincent's Clinical School, UNSW Medicine, Victoria Street, Darlinghurst, NSW, AustraliaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-1838-2310View further author information
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Pages 513-523 | Received 05 Jul 2017, Accepted 12 Oct 2017, Published online: 21 Dec 2017

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Muhammad R. Suleiman, Hanxun Wang, Danxia Huang, Huibin Wang, Johnson Joseph, Tianci Huang, Fengjiao Zhang, Jian Wang & Maosheng Cheng. (2021) Discovery of small molecule inhibitors through pharmacophore modeling, molecular docking, molecular dynamics simulation and experimental validation against myeloid cell leukemia-1 (Mcl-1). Journal of Biomolecular Structure and Dynamics 39:7, pages 2512-2525.
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