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Channels Volume 11, 2017 - Issue 6
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Research Paper

Conservation and variability of the pore-lining helices in P-loop channels

Denis B. TikhonovDepartment of Biophysics of Synaptic Processes, Sechenov Institute of Evolutionary Physiology and Biochemistry, RAS, St. Petersburg, RussiaCorrespondence[email protected]
&
Boris S. ZhorovDepartment of Biophysics of Synaptic Processes, Sechenov Institute of Evolutionary Physiology and Biochemistry, RAS, St. Petersburg, Russia;Department of Biochemistry & Biomedical Sciences, McMaster University, Hamilton, Canada
Pages 660-672 | Received 13 Sep 2017, Accepted 18 Oct 2017, Published online: 01 Dec 2017

Citations (8)

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Read on this site (1)

Denis B. Tikhonov & Boris S. Zhorov. (2020) Intersegment contacts determine geometry of the open and closed states in P-loop channels. Journal of Biomolecular Structure and Dynamics 38:4, pages 1012-1027.
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Articles from other publishers (7)

Koushik Choudhury & Lucie Delemotte. (2023) Modulation of Pore Opening of Eukaryotic Sodium Channels by π-Helices in S6. The Journal of Physical Chemistry Letters 14:25, pages 5876-5881.
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Denis B. Tikhonov & Boris S. Zhorov. (2022) P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models. Membranes 12:2, pages 229.
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Koushik Choudhury, Marina A. Kasimova, Sarah McComas, Rebecca J. Howard & Lucie Delemotte. (2022) An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine. Biophysical Journal 121:1, pages 11-22.
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Denis B. Tikhonov & Boris S. Zhorov. (2021) Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs. International Journal of Molecular Sciences 22:15, pages 8143.
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Denis B. Tikhonov & Boris S. Zhorov. (2020) The pore domain in glutamate-gated ion channels: Structure, drug binding and similarity with potassium channels. Biochimica et Biophysica Acta (BBA) - Biomembranes 1862:10, pages 183401.
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Vyacheslav S. Korkosh, Artem M. Kiselev, Evgeny N. Mikhaylov, Anna A. Kostareva & Boris S. Zhorov. (2019) Atomic Mechanisms of Timothy Syndrome-Associated Mutations in Calcium Channel Cav1.2. Frontiers in Physiology 10.
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Denis B. Tikhonov & Boris S. Zhorov. (2018) Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies. Frontiers in Pharmacology 9.
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