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mAbs Volume 13, 2021 - Issue 1
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Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cells

Sivan Cohena Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USACorrespondence[email protected]
,
Srividya Mynenia Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA
,
Anna Batta Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA
,
Joyce Guerreroa Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA
,
Jochen Brummb Department of Biostatistics, Genentech Inc, South San Francisco, CA, USAORCID Iconhttps://orcid.org/0000-0001-9518-038X
ORCID Icon &
Shan Chunga Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5494-2103
ORCID Icon
Article: 1898831 | Received 11 Dec 2020, Accepted 01 Mar 2021, Published online: 17 Mar 2021

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Yoshiyuki Arata, Shigeki Motoyama, Mariko Yano, Tatsuya Ikuno, Shunsuke Ito, Tomochika Matsushita, Akira Takeiri, Yukari Nishito, Nami Yabuki, Hideaki Mizuno, Zenjiro Sampei, Masayuki Mishima, Masaki Honda, Jumpei Kiyokawa, Hiromi Suzuki, Shuichi Chiba, Mitsuyasu Tabo & Chiyomi Kubo. (2023) Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion. mAbs 15:1.
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Articles from other publishers (2)

Seth G. Thacker, Cheng Her, Logan Kelley-Baker, Derek D C. Ireland, Mohanraj Manangeeswaran, Eric S. Pang & Daniela Verthelyi. (2022) Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients. Frontiers in Immunology 13.
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Sivan Cohen & Shan Chung. (2021) In vitro immunogenicity prediction: bridging between innate and adaptive immunity . Bioanalysis 13:13, pages 1071-1081.
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