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Food Additives & Contaminants: Part A Volume 29, 2012 - Issue 7
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Original Articles

New bolus models for in vivo efficacy testing of mycotoxin-detoxifying agents in relation to EFSA guidelines, assessed using deoxynivalenol in broiler chickens

M. Devreese Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, BelgiumCorrespondence[email protected]
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A. Osselaere Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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J. Goossens Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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V. Vandenbroucke Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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S. De Baere Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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M. Eeckhout Department of Food Science and Technology, Faculty of Biosciences and Landscape Architecture, University College Ghent, Schoonmeersstraat 52, 9000 Ghent, Belgium
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P. De Backer Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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S. Croubels Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
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Pages 1101-1107 | Received 27 Sep 2011, Accepted 26 Feb 2012, Published online: 13 Apr 2012

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Ilse Vanhoutte, Jan Vande Ginste, Stefanie Verstringe, Arnau Vidal, Marthe De Boevre, Sarah De Saeger, Kris Audenaert & Leen De Gelder. (2021) Development of an in vitro gastro-intestinal pig model to screen potential detoxifying agents for the mycotoxin deoxynivalenol. Food Additives & Contaminants: Part A 38:3, pages 488-500.
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Articles from other publishers (22)

Parvathy S Nair, Sivani Menon P S, Shreya Suresh, Sreekanth A J, Sivasabari K, Adithya Krishna S, Anuranj P R, Nayana Krishnan, Parvathy S, Sandip Chakraborty, Hitesh Chopra, Shopnil Akash, Ruhul Amin, Abhijit Dey, Mahmoud Alagawany, Deepak Chandran & Kuldeep Dhama. (2023) Beneficial impacts of biochar as a potential feed additive in animal husbandry. Journal of Experimental Biology and Agricultural Sciences 11:3, pages 479-499.
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Giulia Lo Dico, Siska Croubels, Verónica Carcelén & Maciej Haranczyk. (2022) Machine learning-aided design of composite mycotoxin detoxifier material for animal feed. Scientific Reports 12:1.
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Paul Gerard Bruinenberg & Mathieu Castex. (2021) Evaluation of a Yeast Hydrolysate from a Novel Strain of Saccharomyces cerevisiae for Mycotoxin Mitigation using In Vitro and In Vivo Models. Toxins 14:1, pages 7.
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C. ToniniM.S. OliveiraE.B. ParmeggianiD.A.F. SturzaA.O. MallmannM.I.B. RubinC.A. Mallmann. (2021) Serological biomarkers of zearalenone exposure in beef heifers receiving anti-mycotoxin additive. World Mycotoxin Journal 14:3, pages 357-365.
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Roua Rejeb, Siegrid De Baere, Mathias Devreese, Richard Ducatelle, Siska Croubels, Madiha Hadj Ayed, Achraf Ghorbal & Gunther Antonissen. (2020) Calcination Improves the In Vivo Efficacy of a Montmorillonite Clay to Bind Aflatoxin G1 in Broiler Chickens: A Toxicokinetic Approach. Toxins 12:10, pages 660.
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Paola Battilani, Roberta Palumbo, Paola Giorni, Chiara Dall’Asta, Luca Dellafiora, Athanasios Gkrillas, Piero Toscano, Alfonso Crisci, Carlo Brera, Barbara De Santis, Rosaria Rosanna Cammarano, Maurella Della Seta, Katrina Campbell, Chris Elliot, Armando Venancio, Nelson Lima, Ana Gonçalves, Chloe Terciolo & Isabelle P Oswald. (2020) Mycotoxin mixtures in food and feed: holistic, innovative, flexible risk assessment modelling approach:. EFSA Supporting Publications 17:1.
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Ayman A. Hassan, Salma H. Abu Hafsa, Mona M.M.Y. Elghandour, Poonooru Ravi Kanth Reddy, Jose Cedillo Monroy & Abdelfattah Z.M. Salem. (2019) Dietary Supplementation with sodium bentonite and coumarin alleviates the toxicity of aflatoxin B1 in rabbits. Toxicon 171, pages 35-42.
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Hans-Peter Schmidt, Nikolas Hagemann, Kathleen Draper & Claudia Kammann. (2019) The use of biochar in animal feeding. PeerJ 7, pages e7373.
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Marianne Lauwers, Siska Croubels, Ben Letor, Christos Gougoulias & Mathias Devreese. (2019) Biomarkers for Exposure as A Tool for Efficacy Testing of A Mycotoxin Detoxifier in Broiler Chickens and Pigs. Toxins 11:4, pages 187.
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Francois Stepman. (2018) Scaling-Up the Impact of Aflatoxin Research in Africa. The Role of Social Sciences. Toxins 10:4, pages 136.
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Laura Escrivá, Guillermina Font, Lara Manyes & Houda Berrada. (2017) Studies on the Presence of Mycotoxins in Biological Samples: An Overview. Toxins 9:8, pages 251.
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Lucia Gambacorta, Philippe Pinton, Giuseppina Avantaggiato, Isabelle P. Oswald & Michele Solfrizzo. (2016) Grape Pomace, an Agricultural Byproduct Reducing Mycotoxin Absorption: In Vivo Assessment in Pig Using Urinary Biomarkers. Journal of Agricultural and Food Chemistry 64:35, pages 6762-6771.
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Sophie Fraeyman, Mathias Devreese, Nathan Broekaert, Thomas De Mil, Gunther Antonissen, Siegrid De Baere, Patrick De Backer, Michael Rychlik & Siska Croubels. (2015) Quantitative Determination of Tenuazonic Acid in Pig and Broiler Chicken Plasma by LC-MS/MS and Its Comparative Toxicokinetics. Journal of Agricultural and Food Chemistry 63:38, pages 8560-8567.
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Thomas De Mil, Mathias Devreese, Nathan Broekaert, Sophie Fraeyman, Patrick De Backer & Siska Croubels. (2015) In Vitro Adsorption and in Vivo Pharmacokinetic Interaction between Doxycycline and Frequently Used Mycotoxin Binders in Broiler Chickens. Journal of Agricultural and Food Chemistry 63:17, pages 4370-4375.
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Mathias Devreese, Gunther Antonissen, Patrick De Backer & Siska Croubels. (2014) Efficacy of Active Carbon towards the Absorption of Deoxynivalenol in Pigs. Toxins 6:10, pages 2998-3004.
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Mathias Devreese, George N. Girgis, Si-Trung Tran, Siegrid De Baere, Patrick De Backer, Siska Croubels & Trevor K. Smith. (2014) The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters. Food and Chemical Toxicology 63, pages 69-75.
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Sven Dänicke & Ulrike Brezina. (2013) Kinetics and metabolism of the Fusarium toxin deoxynivalenol in farm animals: Consequences for diagnosis of exposure and intoxication and carry over. Food and Chemical Toxicology 60, pages 58-75.
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Mathias Devreese, Siegrid De Baere, Patrick De Backer & Siska Croubels. (2013) Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography–tandem mass spectrometry. Talanta 106, pages 212-219.
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Mathias Devreese, Frank Pasmans, Patrick De Backer & Siska Croubels. (2013) An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. Toxicology in Vitro 27:1, pages 157-163.
Crossref
Ann Osselaere, Mathias Devreese, Joline Goossens, Virginie Vandenbroucke, Siegrid De Baere, Patrick De Backer & Siska Croubels. (2013) Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens. Food and Chemical Toxicology 51, pages 350-355.
Crossref
Mathias Devreese, Siegrid De Baere, Patrick De Backer & Siska Croubels. (2012) Quantitative determination of several toxicological important mycotoxins in pig plasma using multi-mycotoxin and analyte-specific high performance liquid chromatography–tandem mass spectrometric methods. Journal of Chromatography A 1257, pages 74-80.
Crossref
A. Osselaere, M. Devreese, A. Watteyn, V. Vandenbroucke, J. Goossens, V. Hautekiet, M. Eeckhout, S. De Saeger, S. De Baere, P. De Backer & S. Croubels. (2012) Efficacy and safety testing of mycotoxin-detoxifying agents in broilers following the European Food Safety Authority guidelines. Poultry Science 91:8, pages 2046-2054.
Crossref

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