Advanced search
Publication Cover
Food Additives & Contaminants: Part A Volume 35, 2018 - Issue 6
Submit an article Journal homepage
1,003
Views
34
CrossRef citations to date
0
Altmetric
Articles

Estimated US infant exposures to 3-MCPD esters and glycidyl esters from consumption of infant formula

Judith H. SpungenCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6489-7660
ORCID Icon,
Shaun MacMahonCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USA
,
Jessica LeighCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USAORCID Iconhttps://orcid.org/0000-0002-9348-4854
ORCID Icon,
Brenna FlanneryCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USA
,
Grace KimCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USA
,
Stuart ChirtelCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USA
&
Deborah SmegalCenter for Food Safety and Applied Nutrition (CFSAN), US Food and Drug Administration (FDA), College Park, MD, USA
 show all
Pages 1085-1092 | Received 31 Dec 2017, Accepted 15 Mar 2018, Published online: 14 Jun 2018

Citations (34)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

Son Cao Tran, Ngoc Hong Nguyen, Tu Ngoc Vu, Tien Cao Bui, Ly Cong Phung, Thanh Trung Tran, Hao Thi Hong Le & Thu Nguyen Hung Thai. (2023) Risk assessment of 3-MCPD esters and glycidyl esters from the formulas for infants and young children up to 36 months of age. Food Additives & Contaminants: Part A 40:6, pages 723-732.
Read now
Nik Nur Ashirah Nik Azmi, Thuan-Chew Tan, May Yen Ang & Yin-Hui Leong. (2023) Occurrence and risk assessment of 3-monochloropropanediols esters (3-MCPDE), 2-monochloropropanediol esters (2-MCPDE), and glycidyl esters (GE) in commercial infant formula samples from Malaysia. Food Additives & Contaminants: Part A 40:2, pages 212-221.
Read now
Yonglin Li, Yancai Li, Na Zhang, Shasha Wen, Qi Li, Yuan Gao & Xiuzhu Yu. (2022) Methods, principles, challenges, and perspectives of determining chloropropanols and their esters. Critical Reviews in Food Science and Nutrition 0:0, pages 1-21.
Read now
Jessica K. Beekman, Samanta Popol, Michael Granvogl & Shaun MacMahon. (2021) Occurrence of 3-monochloropropane-1,2-diol (3-MCPD) esters and glycidyl esters in infant formulas from Germany. Food Additives & Contaminants: Part A 38:10, pages 1656-1671.
Read now
Bianca Figueiredo de Mendonça Pereira, Mararlene Ulberg Pereira, Rosana Gomes Ferreira & Bernardete Ferraz Spisso. (2021) Dietary exposure assessment to macrolide antimicrobial residues through infant formulas marketed in Brazil. Food Additives & Contaminants: Part A 38:10, pages 1672-1688.
Read now
Xia Cui, Lei Zhang, Dajin Yang, Jianwen Li, Qing Liu, Haixia Sui, Zhaoping Liu & Pingping Zhou. (2021) Occurrence of 3- and 2-monochloropropanediol esters in infant formulas in China and exposure assessment. Food Additives & Contaminants: Part A 38:9, pages 1470-1480.
Read now
Jessica K. Beekman, Kaitlin Grassi & Shaun MacMahon. (2020) Updated occurrence of 3-monochloropropane-1,2-diol esters (3-MCPD) and glycidyl esters in infant formulas purchased in the United States between 2017 and 2019. Food Additives & Contaminants: Part A 37:3, pages 374-390.
Read now

Articles from other publishers (27)

Zhengchao Shen, Kexin Tian, Muhammad Mujahid Ali, Sifan Mei, Xin Ma, Jiang Liang, Feng Pan, Jianwen Li, Haixia Sui & Zhenxia Du. (2023) The occurrence and probabilistic risk assessment of 3-MCPDEs and GEs in infant formulas from Chinese market employing Monte Carlo simulation technique. Food and Chemical Toxicology 179, pages 113978.
Crossref
Sharifah Shahira Syed Putra, Wan Jefrey Basirun, Amal A. M. Elgharbawy, Maan Hayyan, Waleed Al Abdulmonem, Abdullah S. M. Aljohani & Adeeb Hayyan. (2023) 3-Monochloropropane-1,2-diol (3-MCPD): a review on properties, occurrence, mechanism of formation, toxicity, analytical approach and mitigation strategy. Journal of Food Measurement and Characterization 17:4, pages 3592-3615.
Crossref
Eva Kruger, Eman A. Toraih, Mohammad H. Hussein, Shaimaa A. Shehata, Amani Waheed, Manal S. Fawzy & Emad Kandil. (2022) Thyroid Carcinoma: A Review for 25 Years of Environmental Risk Factors Studies. Cancers 14:24, pages 6172.
Crossref
Sabrina S. Andrade, Klícia A. Sampaio, Mariana C. Costa, Pedro P. Corbi, Antonio J.A. Meirelles & Guilherme J. Maximo. (2022) Solid-liquid equilibrium of free form of oil contaminants (3-MCPD and glycidol) in lipidic systems. Food Research International 160, pages 111740.
Crossref
Shaun MacMahon. 2022. Processing Contaminants in Edible Oils. Processing Contaminants in Edible Oils 1 6 .
Shaun MacMahon, Jessica Beekman & Michael Granvogl. 2022. Processing Contaminants in Edible Oils. Processing Contaminants in Edible Oils 195 219 .
Jinglin Zhang, Wendi Zhang, Yuanzheng Zhang, Mingquan Huang & Baoguo Sun. (2021) Effects of Food Types, Frying Frequency, and Frying Temperature on 3-Monochloropropane-1,2-diol Esters and Glycidyl Esters Content in Palm Oil during Frying. Foods 10:10, pages 2266.
Crossref
Didah Nur Faridah, Masayu Nur Ulfa & Nuri Andarwulan. (2021) The comparison of several lipid extraction methods on infant formula for 3‐monochloropropanediol esters and glycidyl esters analysis. International Journal of Food Science & Technology 56:9, pages 4730-4737.
Crossref
Yuan Zhao, Yinjuan Xu, Lixia Shi & Ying Fan. (2021) Perovskite Nanomaterial-Engineered Multiplex-Mode Fluorescence Sensing of Edible Oil Quality. Analytical Chemistry 93:31, pages 11033-11042.
Crossref
Shujie Wang, Guoqin Liu & Weiwei Cheng. (2021) Chloride-mediated co-formation of 3-monochloropropanediol esters and glycidyl esters in both model vegetable oils and chemical model systems. Food Research International 140, pages 109879.
Crossref
Miriam E. Mossoba, Mapa S.T. Mapa, Jessica Sprando, Magali Araujo & Robert L. Sprando. (2021) Evaluation of transporter expression in HK-2 cells after exposure to free and ester-bound 3-MCPD. Toxicology Reports 8, pages 436-442.
Crossref
Kok Ming Goh, Yu Hua Wong, Chin Ping Tan & Kar Lin Nyam. (2021) A summary of 2-, 3-MCPD esters and glycidyl ester occurrence during frying and baking processes. Current Research in Food Science 4, pages 460-469.
Crossref
Maria Beatriz Abreu Gloria, Lilia Masson, Jaime Amaya-Farfan & Delia B. Rodriguez-Amaya. 2021. Chemical Changes During Processing and Storage of Foods. Chemical Changes During Processing and Storage of Foods 453 535 .
Boyan Gao, Mengchu Jin, Wenhao Zheng, Yaqiong Zhang & Liangli Lucy Yu. (2020) Current Progresses on Monochloropropane Diol Esters in 2018–2019 and Their Future Research Trends. Journal of Agricultural and Food Chemistry 68:46, pages 12984-12992.
Crossref
Wiwi Hartuti, Nuri Andarwulan & Puspo Edi Giriwono. (2020) Kajian Paparan dan Risiko 3-MCPDE dan GE dari Produk Formula pada Bayi Usia 0-12 Bulan di Indonesia secara Probabilistik. Jurnal Mutu Pangan : Indonesian Journal of Food Quality 7:2, pages 59-66.
Crossref
Magali Araujo, Jessica K. Beekman, Mapa S.T. Mapa, Shaun MacMahon, Yang Zhao, Thomas J. Flynn, Brenna Flannery, Miriam E. Mossoba & Robert L. Sprando. (2020) Assessment of intestinal absorption/metabolism of 3-chloro-1,2-propanediol (3-MCPD) and three 3-MCPD monoesters by Caco-2 cells. Toxicology in Vitro 67, pages 104887.
Crossref
Bianca Figueiredo de Mendonça Pereira, Cristine Couto de Almeida, Katia Christina Leandro, Marion Pereira da Costa, Carlos Adam Conte‐Junior & Bernardete Ferraz Spisso. (2020) Occurrence, sources, and pathways of chemical contaminants in infant formulas. Comprehensive Reviews in Food Science and Food Safety 19:4, pages 1378-1396.
Crossref
Miriam E. Mossoba, Mapa S. T. Mapa, Magali Araujo, Yang Zhao, Brenna Flannery, Thomas Flynn, Jessica Sprando, Paddy Wiesenfeld & Robert L. Sprando. (2019) In vitro toxicological assessment of free 3-MCPD and select 3-MCPD esters on human proximal tubule HK-2 cells. Cell Biology and Toxicology 36:3, pages 209-221.
Crossref
Khanh Hoang Nguyen & Arvid Fromberg. (2020) Monochloropropanediol and glycidyl esters in infant formula and baby food products on the Danish market: Occurrence and preliminary risk assessment. Food Control 110, pages 106980.
Crossref
Xiaoqiang Zou, Hong Zhang, Jacob Nedergaard Pedersen, Hai Zhang, Xiangyu Wang, Juan Yang, Xuebing Xu & Zheng Guo. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 55 .
Miriam E. Mossoba, Mapa S.T. Mapa, Magali Araujo, Yang Zhao, Brenna Flannery, Thomas Flynn, Jessica Sprando, Paddy Wiesenfeld & Robert L. Sprando. (2020) Long-term <i>in vitro</i> effects of exposing the human HK-2 proximal tubule cell line to 3-monochloropropane-1,2-diol. The Journal of Toxicological Sciences 45:1, pages 45-56.
Crossref
Mapa S.T. Mapa, Magali Araujo, Yang Zhao, Thomas Flynn, Jessica Sprando, Paddy Wiesenfeld, Robert L. Sprando & Miriam E. Mossoba. (2020) A method to dissolve 3-MCPD mono- and di-esters in aqueous cell culture media. MethodsX 7, pages 100774.
Crossref
Shaun MacMahon & Jessica Beekman. (2019) 3-Chloro-1,2-propanediol (3-MCPD), 2-chloro-1,3-propanediol (2-MCPD) and glycidyl esters in infant formula: a review. Current Opinion in Food Science 30, pages 67-72.
Crossref
Biow Ing Sim, Yu Hua Wong & Chin Ping Tan. 2019. Mitigating Contamination from Food Processing. Mitigating Contamination from Food Processing 152 190 .
Willian Cruzeiro Silva, Roseli Aparecida Ferrari, Eduardo Vicente, Klicia Araujo Sampaio & Adriana Pavesi Arisseto. 2019. Mitigating Contamination from Food Processing. Mitigating Contamination from Food Processing 108 127 .
Graham A. Bonwick & Catherine S. Birch. 2019. Mitigating Contamination from Food Processing. Mitigating Contamination from Food Processing 1 16 .
Maria Fiore, Gea Oliveri Conti, Rosario Caltabiano, Antonino Buffone, Pietro Zuccarello, Livia Cormaci, Matteo Angelo Cannizzaro & Margherita Ferrante. (2019) Role of Emerging Environmental Risk Factors in Thyroid Cancer: A Brief Review. International Journal of Environmental Research and Public Health 16:7, pages 1185.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.