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Statistics in Biopharmaceutical Research Volume 12, 2020 - Issue 4
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Letter to the Editor

The Hazards of Period Specific and Weighted Hazard Ratios

Jonathan W. BartlettDepartment of Mathematical Sciences, University of Bath, Bath, UK; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-7117-0195
ORCID Icon,
Tim P. MorrisMRC Clinical Trials Unit at UCL, London, UK;
,
Mats J. StensrudDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts; ;Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway;
,
Rhian M. DanielDivision of Population Medicine, Cardiff University, Cardiff, UK;
,
Stijn K. VansteelandtDepartment of Applied Mathematics, Computer Science and Statistics, Ghent University, Gent, Belgium; ;Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK;
&
Carl-Fredrik BurmanData Science & AI, AstraZeneca R&D Gothenburg, Goteborg, Sweden
Pages 518-519 | Received 20 Mar 2020, Accepted 03 Apr 2020, Published online: 23 Jun 2020

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Yuan-Li Shen, Sirisha Mushti, Flora Mulkey, Thomas Gwise, Xin Wang, Jiaxi Zhou, Xin Gao, Shenghui Tang, Marc R. Theoret, Richard Pazdur & Rajeshwari Sridhara. (2023) Rejoinder to Comments on “Non-Proportional Hazards – An Evaluation of the MaxCombo Test in Cancer Clinical Trials”. Statistics in Biopharmaceutical Research 15:2, pages 315-317.
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Martin Posch, Robin Ristl & Franz König. (2023) Testing and Interpreting the “Right” Hypothesis—Comment on “Non-proportional Hazards — An Evaluation of the MaxCombo Test in Cancer Clinical Trials”. Statistics in Biopharmaceutical Research 15:2, pages 310-311.
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Satrajit Roychoudhury, Keaven M Anderson, Jiabu Ye & Pralay Mukhopadhyay. (2023) Robust Design and Analysis of Clinical Trials With Nonproportional Hazards: A Straw Man Guidance From a Cross-Pharma Working Group. Statistics in Biopharmaceutical Research 15:2, pages 280-294.
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Zihan Lin, Dan Zhao, Junjing Lin, Ai Ni & Jianchang Lin. (2022) Statistical methods of indirect comparison with real-world data for survival endpoint under non-proportional hazards. Journal of Biopharmaceutical Statistics 32:4, pages 582-599.
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Ray S. Lin, Ji Lin, Satrajit Roychoudhury, Keaven M. Anderson, Tianle Hu, Bo Huang, Larry F. Leon, Jason J. Z. Liao, Rong Liu, Xiaodong Luo, Pralay Mukhopadhyay, Rui Qin, Kay Tatsuoka, Xuejing Wang, Yang Wang, Jian Zhu, Tai-Tsang Chen & Renee Iacona. (2020) Rejoinder to Letter to the Editor “The Hazards of Period Specific and Weighted Hazard Ratios”. Statistics in Biopharmaceutical Research 12:4, pages 520-521.
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Articles from other publishers (10)

Yi‐Cheng Tai, Weijing Wang & Martin T. Wells. (2023) Two‐sample inference procedures under nonproportional hazards . Pharmaceutical Statistics 22:6, pages 1016-1030.
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Alessandra Verzelloni Sef, Siân I Jaggar, Vladimir Trkulja, Rafael Alonso-Gonzalez, Davorin Sef & Marko I Turina. (2023) Factors associated with long-term outcomes in adult congenital heart disease patients with infective endocarditis: a 16-year tertiary single-centre experience. European Journal of Cardio-Thoracic Surgery 63:5.
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Michele Santacatterina. (2023) Robust weights that optimally balance confounders for estimating marginal hazard ratios. Statistical Methods in Medical Research 32:3, pages 524-538.
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Kim M. Jachno, Stephane Heritier, Robyn L. Woods, Suzanne Mahady, Andrew Chan, Andrew Tonkin, Anne Murray, John J. McNeil & Rory Wolfe. (2022) Examining evidence of time-dependent treatment effects: an illustration using regression methods. Trials 23:1.
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Kaihuan Qian & Xiaohua Zhou. (2022) Weighted Log-Rank Test for Clinical Trials with Delayed Treatment Effect Based on a Novel Hazard Function Family. Mathematics 10:15, pages 2573.
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Dominic Magirr & José L Jiménez. (2022) Design and analysis of group-sequential clinical trials based on a modestly weighted log-rank test in anticipation of a delayed separation of survival curves: A practical guidance. Clinical Trials 19:2, pages 201-210.
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Torben Martinussen. (2022) Causality and the Cox Regression Model. Annual Review of Statistics and Its Application 9:1, pages 249-259.
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José L. Jiménez, Julia Niewczas, Alexander Bore & Carl-Fredrik Burman. (2021) A modified weighted log-rank test for confirmatory trials with a high proportion of treatment switching. PLOS ONE 16:11, pages e0259178.
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Revathi Ananthakrishnan, Stephanie Green, Alessandro Previtali, Rong Liu, Daniel Li & Michael LaValley. (2021) Critical review of oncology clinical trial design under non-proportional hazards. Critical Reviews in Oncology/Hematology 162, pages 103350.
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Dominic Magirr. (2020) Non‐proportional hazards in immuno‐oncology: Is an old perspective needed?. Pharmaceutical Statistics 20:3, pages 512-527.
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