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IIE Transactions on Healthcare Systems Engineering Volume 2, 2012 - Issue 1
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ORIGINAL ARTICLES

A Monte Carlo approach to the estimation & analysis of uncertainty in clinical laboratory measurement processes

Varun Ramamohan School of Industrial Engineering, Purdue University, 315 N Grant St., West Lafayette, IN, 47907, USA
,
Vishal Chandrasekar School of Industrial Engineering, Purdue University, 315 N Grant St., West Lafayette, IN, 47907, USA
,
Jim Abbott Clinical Support Group, Roche Diagnostics Corporation, Indianapolis, IN, USA
,
George G. Klee Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, MN, USA
&
Yuehwern Yih School of Industrial Engineering, Purdue University, 315 N Grant St., West Lafayette, IN, 47907, USA
Pages 1-13 | Received 01 Nov 2010, Accepted 01 Feb 2012, Published online: 09 May 2012

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Varun Ramamohan, James T. Abbott, George G. Klee & Yuehwern Yih. (2015) Modeling the effect of instrument drift in clinical laboratories: A serum bilirubin assay case study. IIE Transactions on Healthcare Systems Engineering 5:3, pages 147-164.
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Articles from other publishers (8)

Matteo Vidali. (2023) Use of Computer Simulation for Calculating Reference Limits for Distribution Overlap. The Journal of Applied Laboratory Medicine 8:1, pages 106-112.
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Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee & Hye Ryoun Kim. (2021) Estimation of Measurement Uncertainty of Factor Assays Using the Monte Carlo Simulation. American Journal of Clinical Pathology 156:5, pages 717-721.
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Satheesh Natarajan, Maria C. DeRosa, Malay Ilesh Shah & Joseph Jayaraj. (2021) Development and Evaluation of a Quantitative Fluorescent Lateral Flow Immunoassay for Cystatin-C, a Renal Dysfunction Biomarker. Sensors 21:9, pages 3178.
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Hui Yang & Eva K. LeeVarun Ramamohan, James T. Abbott & Yuehwern Yih. 2016. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement 127 157 .
Varun Ramamohan, James T. Abbott & Yuehwern Yih. (2015) A mathematical model of measurement uncertainty of single substrate enzyme assays. Journal of Chemometrics 29:1, pages 49-58.
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Varun Ramamohan, James T. Abbott & Yuehwern Yih. (2014) A simulation-based approach to modeling the uncertainty of two-substrate clinical enzyme measurement processes. A simulation-based approach to modeling the uncertainty of two-substrate clinical enzyme measurement processes.
Varun Ramamohan, James T. Abbott, George G. Klee & Yuehwern Yih. (2014) Modeling, analysis and optimization of calibration uncertainty in clinical laboratories. Measurement 50, pages 175-185.
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Varun Ramamohan, Yuehwern Yih, James T. Abbott & George G. Klee. (2013) Category-specific uncertainty modeling in clinical laboratory measurement processes. Clinical Chemistry and Laboratory Medicine (CCLM) 51:12, pages 2273-2280.
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