Advanced search
Publication Cover
Nucleus Volume 9, 2018 - Issue 1
Submit an article Journal homepage
3,527
Views
42
CrossRef citations to date
0
Altmetric
Special issue on laminopathies

Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation

Nolwenn BriandDepartment of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, NorwayView further author information
&
Philippe CollasDepartment of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway;Norwegian Center for Stem Cell Research, Department of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, NorwayCorrespondence[email protected]
View further author information
Pages 216-226 | Received 02 Jan 2018, Accepted 02 Mar 2018, Published online: 02 Apr 2018

Citations (42)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Garrett T. Santini, Parisha P. Shah, Ashley Karnay & Rajan Jain. (2022) Aberrant chromatin organization at the nexus of laminopathy disease pathways. Nucleus 13:1, pages 302-314.
Read now
Manindra Bera & Kaushik Sengupta. (2020) Nuclear filaments: role in chromosomal positioning and gene expression. Nucleus 11:1, pages 99-110.
Read now

Articles from other publishers (40)

Amnon Buxboim, Rafael Kronenberg‐Tenga, Sarka Salajkova, Nili Avidan, Hen Shahak, Alice Thurston & Ohad Medalia. (2023) Scaffold, mechanics and functions of nuclear lamins. FEBS Letters.
Crossref
Hiroki Yamaguchi, R. Ariel Gomez & Maria Luisa S. Sequeira-Lopez. (2023) Renin Cells, From Vascular Development to Blood Pressure Sensing. Hypertension 80:8, pages 1580-1589.
Crossref
Yichi Zhang, Andres Ramirez-Martinez, Kenian Chen, John R. McAnally, Chunyu Cai, Mateusz Z. Durbacz, Francesco Chemello, Zhaoning Wang, Lin Xu, Rhonda Bassel-Duby, Ning Liu & Eric N. Olson. (2023) Net39 protects muscle nuclei from mechanical stress during the pathogenesis of Emery-Dreifuss muscular dystrophy. Journal of Clinical Investigation 133:13.
Crossref
Maria Chatzifrangkeskou, Caroline Le Dour & Antoine Muchir. (2023) Modulation of cytoskeleton in cardiomyopathy caused by mutations in LMNA gene . American Journal of Physiology-Cell Physiology 324:6, pages C1223-C1235.
Crossref
Parisha P. Shah, Garrett T. Santini, Kaitlyn M. Shen & Rajan Jain. (2023) InterLINCing Chromatin Organization and Mechanobiology in Laminopathies. Current Cardiology Reports 25:5, pages 307-314.
Crossref
Natalia M. Galigniana, Marina C. Ruiz & Graciela Piwien‐Pilipuk. (2022) FK506 binding protein 51: Its role in the adipose organ and beyond. Journal of Cellular Biochemistry.
Crossref
Jan Padeken, Stephen P. Methot & Susan M. Gasser. (2022) Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance. Nature Reviews Molecular Cell Biology 23:9, pages 623-640.
Crossref
Justin J. Rochford. (2022) When Adipose Tissue Lets You Down: Understanding the Functions of Genes Disrupted in Lipodystrophy. Diabetes 71:4, pages 589-598.
Crossref
Lei Chang, Mengfan Li, Shipeng Shao, Chen Li, Shanshan Ai, Boxin Xue, Yingping Hou, Yiwen Zhang, Ruifeng Li, Xiaoying Fan, Aibin He, Cheng Li & Yujie Sun. (2020) Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells. Protein & Cell 13:4, pages 258-280.
Crossref
Xianrong Wong, Ashley J. Melendez-Perez & Karen L. Reddy. (2022) The Nuclear Lamina. Cold Spring Harbor Perspectives in Biology 14:2, pages a040113.
Crossref
Duhita Sengupta, Sk Nishan Ali, Aditya Bhattacharya, Joy Mustafi, Asima Mukhopadhyay & Kaushik Sengupta. (2022) A deep hybrid learning pipeline for accurate diagnosis of ovarian cancer based on nuclear morphology. PLOS ONE 17:1, pages e0261181.
Crossref
Joanna M. Bridger, Rita Torres Pereira, Cristina Pina, Sabrina Tosi & Annabelle Lewis. 2022. Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine. Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine 71 102 .
Julien L. P. Morival, Halida P. Widyastuti, Cecilia H. H. Nguyen, Michael V. Zaragoza & Timothy L. Downing. (2021) DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies. Clinical Epigenetics 13:1.
Crossref
Luis F. Flores, Brooke R. Tader, Ezequiel J. Tolosa, Ashley N. Sigafoos, David L. Marks & Martin E. Fernandez-Zapico. (2021) Nuclear Dynamics and Chromatin Structure: Implications for Pancreatic Cancer. Cells 10:10, pages 2624.
Crossref
Hirofumi Watanabe, Brian C. BelyeaRobert L. PaxtonMinghong LiBette J. DzambaDouglas W. DeSimoneR. Ariel GomezMaria Luisa S. Sequeira-Lopez. (2021) Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis. Circulation Research 129:2, pages 262-276.
Crossref
Xudong Zhu, Zhiyang Chen, Weiyan Shen, Gang Huang, John M. Sedivy, Hu Wang & Zhenyu Ju. (2021) Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention. Signal Transduction and Targeted Therapy 6:1.
Crossref
Antonio Atalaia, Rabah Ben Yaou, Karim Wahbi, Annachiara De Sandre-Giovannoli, Corinne Vigouroux & Gisèle Bonne. (2021) Laminopathies’ Treatments Systematic Review: A Contribution Towards a ‘Treatabolome’. Journal of Neuromuscular Diseases 8:3, pages 419-439.
Crossref
Wenjun Pu, Haihui Zhang, Peiwu Qin & Lin Deng. (2021) Nuclear envelope integrity, DNA replication, damage repair and genome stability. Genome Instability & Disease 2:2, pages 102-114.
Crossref
Brandon L. Walling & Philip M. Murphy. (2021) Protean Regulation of Leukocyte Function by Nuclear Lamins. Trends in Immunology 42:4, pages 323-335.
Crossref
Victoria E Hoskins, Kristiana Smith & Karen L Reddy. (2021) The shifting shape of genomes: dynamics of heterochromatin interactions at the nuclear lamina. Current Opinion in Genetics & Development 67, pages 163-173.
Crossref
Andres Ramirez-Martinez, Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin K. Cenik, John R. McAnally, Chunyu Cai, John M. Shelton, Jian Huang, Ana Brennan, Bret M. Evers, Pradeep P. A. Mammen, Lin Xu, Rhonda Bassel-Duby, Ning Liu & Eric N. Olson. (2021) The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. Nature Communications 12:1.
Crossref
Federica Lucini, Andrea Bianchi & Chiara Lanzuolo. 2021. Capturing Chromosome Conformation. Capturing Chromosome Conformation 173 195 .
Endre Sebestyén, Fabrizia Marullo, Federica Lucini, Cristiano Petrini, Andrea Bianchi, Sara Valsoni, Ilaria Olivieri, Laura Antonelli, Francesco Gregoretti, Gennaro Oliva, Francesco Ferrari & Chiara Lanzuolo. (2020) SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome. Nature Communications 11:1.
Crossref
Elena V. Ignatieva, Oksana A. Ivanova, Margarita Y. Komarova, Natalia V. Khromova, Dmitrii E. Polev, Anna A. Kostareva, Alexey Sergushichev & Renata I. Dmitrieva. (2020) LMNA Mutations G232E and R482L Cause Dysregulation of Skeletal Muscle Differentiation, Bioenergetics, and Metabolic Gene Expression Profile. Genes 11:9, pages 1057.
Crossref
Vittoria Cenni, Cristina Capanni, Elisabetta Mattioli, Elisa Schena, Stefano Squarzoni, Maria Giulia Bacalini, Paolo Garagnani, Stefano Salvioli, Claudio Franceschi & Giovanna Lattanzi. (2020) Lamin A involvement in ageing processes. Ageing Research Reviews 62, pages 101073.
Crossref
Chad M. Hobson & Andrew D. Stephens. (2020) Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications. Cells 9:7, pages 1623.
Crossref
Silvia Crasto, Ilaria My & Elisa Di Pasquale. (2020) The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype. Frontiers in Physiology 11.
Crossref
Salvatore Fioriniello, Domenico Marano, Francesca Fiorillo, Maurizio D’Esposito & Floriana Della Ragione. (2020) Epigenetic Factors that Control Pericentric Heterochromatin Organization in Mammals. Genes 11:6, pages 595.
Crossref
Erica M. Hildebrand & Job Dekker. (2020) Mechanisms and Functions of Chromosome Compartmentalization. Trends in Biochemical Sciences 45:5, pages 385-396.
Crossref
Andrea Bianchi, Chiara Mozzetta, Gloria Pegoli, Federica Lucini, Sara Valsoni, Valentina Rosti, Cristiano Petrini, Alice Cortesi, Francesco Gregoretti, Laura Antonelli, Gennaro Oliva, Marco De Bardi, Roberto Rizzi, Beatrice Bodega, Diego Pasini, Francesco Ferrari, Claudia Bearzi & Chiara Lanzuolo. (2020) Dysfunctional polycomb transcriptional repression contributes to lamin A/C–dependent muscular dystrophy. Journal of Clinical Investigation 130:5, pages 2408-2421.
Crossref
Chiara Mozzetta & Francesco Saverio Tedesco. (2019) Challenging the “chromatin hypothesis” of cardiac laminopathies with LMNA mutant iPS cells . Journal of Cell Biology 218:9, pages 2826-2828.
Crossref
Andrew J. Fritz, Nitasha Sehgal, Artem Pliss, Jinhui Xu & Ronald Berezney. (2019) Chromosome territories and the global regulation of the genome. Genes, Chromosomes and Cancer 58:7, pages 407-426.
Crossref
Philippe Collas, Tharvesh M. Liyakat Ali, Annaël Brunet & Thomas Germier. (2019) Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains. Frontiers in Genetics 10.
Crossref
Nicolò Salvarani, Silvia Crasto, Michele Miragoli, Alessandro Bertero, Marianna Paulis, Paolo Kunderfranco, Simone Serio, Alberto Forni, Carla Lucarelli, Matteo Dal Ferro, Veronica Larcher, Gianfranco Sinagra, Paolo Vezzoni, Charles E. Murry, Giuseppe Faggian, Gianluigi Condorelli & Elisa Di Pasquale. (2019) The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy. Nature Communications 10:1.
Crossref
Wedad Al-Qahtani, Mai Abduljabbar, Entissar AlSuhaibani, Anas Abdel Rahman & Ahmad Aljada. (2019) Quantification of the Lamin A/C Transcript Variants in Cancer Cell Lines by Targeted Absolute Quantitative Proteomics and Correlation with mRNA Expression. International Journal of Molecular Sciences 20:8, pages 1902.
Crossref
Kseniya Perepelina, Polina Klauzen, Anna Kostareva & Anna Malashicheva. (2019) Tissue-Specific Influence of Lamin A Mutations on Notch Signaling and Osteogenic Phenotype of Primary Human Mesenchymal Cells. Cells 8:3, pages 266.
Crossref
Francesca Chiarini, Camilla Evangelisti, Vittoria Cenni, Antonietta Fazio, Francesca Paganelli, Alberto Martelli & Giovanna Lattanzi. (2019) The Cutting Edge: The Role of mTOR Signaling in Laminopathies. International Journal of Molecular Sciences 20:4, pages 847.
Crossref
Rosettia Ho & Robert A. Hegele. (2018) Complex effects of laminopathy mutations on nuclear structure and function. Clinical Genetics 95:2, pages 199-209.
Crossref
So-mi Kang, Min-Ho Yoon & Bum-Joon Park. (2018) Laminopathies; Mutations on single gene and various human genetic diseases. BMB Reports 51:7, pages 327-337.
Crossref
Elizabeth Mazzio & Karam F. A. Soliman. 2018. Genomics-Driven Healthcare. Genomics-Driven Healthcare 263 279 .

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.