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Journal of Plastic Surgery and Hand Surgery Volume 54, 2020 - Issue 5
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Resveratrol inhibits proliferation and promotes apoptosis of keloid fibroblasts by targeting HIF-1α

Loubin SiDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Mingzi ZhangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Enling GuanDepartment of Ear-Nose-Throat, Qingdao Huangdao District Hospital of Traditional Chinese Medicine, Shandong, China; View further author information
,
Qin HanDepartment of Ear-Nose-Throat, Qingdao Huangdao District Hospital of Traditional Chinese Medicine, Shandong, China; View further author information
,
Yifang LiuInternational Education College, Beijing Vocational College of Agriculture, Beijing, ChinaView further author information
,
Xiao LongDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Fei LongDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Robert Chun-Hua ZhaoCenter of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; View further author information
,
Jiuzuo HuangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Zhifei LiuDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Ru ZhaoDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
,
Hailin ZhangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; View further author information
&
Xiaojun WangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Beijing, China; Correspondence[email protected]
View further author information
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Pages 290-296 | Received 14 Feb 2020, Accepted 15 May 2020, Published online: 04 Jun 2020

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Ming-Zi Zhang, Xin-Hang Dong, Wen-Chao Zhang, Ming Li, Lou-Bin Si, Yi-Fang Liu, Hao-Ran Li, Peng-Xiang Zhao, Meng-Yu Liu, Yao Mawulikplimi Adzavon, Xiao-Jun Wang, Xiao Long & Yu Ding. (2023) A comparison of proliferation levels in normal skin, physiological scar and keloid tissue. Journal of Plastic Surgery and Hand Surgery 57:1-6, pages 122-128.
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Articles from other publishers (12)

Yuncheng Tai, Liying Zheng, Jiao Liao, Zixiong Wang & Lai Zhang. (2023) Roles of the HIF-1α pathway in the development and progression of keloids. Heliyon 9:8, pages e18651.
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Pu Wang, Qifei Wang, Xin Yang, Yang An, Jingyi Wang, Fangfei Nie, Bailin Pan, Hongsen Bi & Zelian Qin. (2023) Targeting the Glycolytic Enzyme PGK1 to Inhibit the Warburg Effect: A New Strategy for Keloid Therapy. Plastic & Reconstructive Surgery 151:6, pages 970e-980e.
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Zi‐kai Qiu, Ming‐zi Zhang, Wen‐chao Zhang, Zhi‐jin Li, Lou‐bin Si, Xiao Long, Nan‐ze Yu & Xiao‐jun Wang. (2023) Role of HIF ‐1α in pathogenic mechanisms of keloids . Journal of Cosmetic Dermatology 22:5, pages 1436-1448.
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Yun Liu, Lei Li, Jia-Yao Wang, Fei Gao, Xia Lin, Shi-Shuai Lin, Zhi-Yang Qiu & Zun-Hong Liang. (2022) LncRNA GNAS-AS1 knockdown inhibits keloid cells growth by mediating the miR-188-5p/RUNX2 axis. Molecular and Cellular Biochemistry 478:4, pages 707-719.
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Hongyan Liao, Jiagui Huang, Jie Liu, Yue Chen, Huimin Zhu, Xuemei Li, Jun Wen, Qin Xiang & Qin Yang. (2023) Resveratrol Inhibits Activation of Microglia after Stroke through Triggering Translocation of Smo to Primary Cilia. Journal of Personalized Medicine 13:2, pages 268.
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Jianwu Fan, Shuang Wei, Xiaoyan Zhang, Li Chen, Xin Zhang, Yaping Jiang, Minjie Sheng & Yihui Chen. (2023) Resveratrol inhibits TGF-β1–induced fibrotic effects in human pterygium fibroblasts. Environmental Health and Preventive Medicine 28:0, pages 59-59.
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Jing Zhang, Jian Ping, Na Jiang & Lieming Xu. (2022) Resveratrol inhibits hepatic stellate cell activation by regulating autophagy and apoptosis through the SIRT1 and JNK signaling pathways . Journal of Food Biochemistry 46:12.
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Shuangfei Liu, Huan Yang, Jinru Song, Yue Zhang, Ahmed T. H. Abualhssain & Bin Yang. (2022) Keloid: Genetic susceptibility and contributions of genetics and epigenetics to its pathogenesis. Experimental Dermatology 31:11, pages 1665-1675.
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Yuan Jia, Jia-Hao Shao, Kai-Wen Zhang, Ming-Li Zou, Ying-Ying Teng, Fan Tian, Meng-Nan Chen, Wei-Wei Chen, Zheng-Dong Yuan, Jun-Jie Wu & Feng-Lai Yuan. (2022) Emerging Effects of Resveratrol on Wound Healing: A Comprehensive Review. Molecules 27:19, pages 6736.
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Yijun Xia, Youbin Wang, Mengjie Shan, Yan Hao, Hao Liu, Qiao Chen & Zhengyun Liang. (2022) Advances in the pathogenesis and clinical application prospects of tumor biomolecules in keloid. Burns & Trauma 10.
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Ming‐Shiuan Nien, Wen‐Pin Cheng, Jun Feng & Yong‐Yan Cui. (2021) The molecular mechanism of GADD153 in apoptosis of keloid fibroblasts exposed to botulinum toxin type A. Journal of Cellular and Molecular Medicine 25:19, pages 9402-9410.
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Xiao Wang, Lei Liu, Duyin Jiang, Shuliang Lu, Yingkai Liu, Wei Dong, Yongjun Qi, Jixun Zhang, Ya Jiao, Hongmin Gong, Wei Wang & Xiaochuan Wang. 2021. Regenerative Medicine in China. Regenerative Medicine in China 179 192 .

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