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Journal of Community Hospital Internal Medicine Perspectives Volume 7, 2017 - Issue 4

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Case Reports

Ventricular fibrillation due to overdose of loperamide, the “poor man’s methadone”

Amr SalamaDepartment of Medicine, Unity Hospital, Rochester, NY, USACorrespondence[email protected]

Yana LevinDepartment of Medicine, Unity Hospital, Rochester, NY, USA

Pramod JhaDepartment of Medicine, Unity Hospital, Rochester, NY, USA

Richard AlweisDepartment of Medicine, Unity Hospital, Rochester, NY, USA;Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA;School of Health Sciences, Rochester Institute of Technology, Rochester, NY, USA

Pages 222-226 | Received 03 Apr 2017, Accepted 27 Jun 2017, Published online: 19 Sep 2017

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https://doi.org/10.1080/20009666.2017.1351290
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Hua Rong Lu, Bruce P. Damiano, Mohamed Kreir, Jutta Rohrbacher, Henk van der Linde, Tamerlan Saidov, Ard Teisman & David J. Gallacher. (2023) The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose. Biomolecules 13:9, pages 1355.
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Farshid Etaee, Morgan Tobin, Suchith Vuppala, Alireza Komaki, Brian P. Delisle, Luigi Di Biase, John N Catanzaro, Andrea Natale & Claude S. Elayi. (2021) Effects of opioid receptor agonist and antagonist medications on electrocardiogram changes and presentation of cardiac arrhythmia: review article. Journal of Interventional Cardiac Electrophysiology 63:2, pages 471-500.
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Raunak Mohan Nair, Bahaa Abdelghaffar & Roy Chung. (2022) Loperamide Overdose With Ventricular Tachycardia Storm. American Journal of Therapeutics 29:1, pages e129-e131.
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Miguel A. Rojas Carrera, Juan Guzman Olea, Gabriel Guzman Olea & Ernesto Hernandez Jimenez. (2021) A life-threatening ventricular arrhythmia secondary to loperamide abuse, “a poor man’s methadone”. Heart, Vessels and Transplantation 5:Issue 2, pages 75.
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Bridget Onders & Kurt Neltner. 2020. Case Studies in Emergency Medicine. Case Studies in Emergency Medicine 341 349 .

Kasha Bornstein, Timothy Montrief & Mehruba Anwar Parris. (2019) Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose. Clinical Practice and Cases in Emergency Medicine 3:3, pages 262-266.
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Lee A. Wolfrum, Aimee S. Nordmeyer, Christopher W. Racine & Stephanie D. Nichols. (2019) Loperamide-Associated Opioid Use Disorder and Proposal of an Alternative Treatment with Buprenorphine. Journal of Addiction Medicine 13:3, pages 245-247.
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Kolawole A. Olofinsan, Rafiat A. Ajala‐Lawal & Taofeek O. Ajiboye. (2018) Loperamide‐induced cardiotoxicity in rats: Evidence from cardiac and oxidative stress biomarkers. Journal of Biochemical and Molecular Toxicology 33:4.
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Amr Idris, Danielle C. Mihora & Kenji Kaye. (2018) Loperamide abuse cardiotoxicity. Should loperamide still be an over the counter medication?. The American Journal of Emergency Medicine 36:9, pages 1716.e1-1716.e3.
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Kirk L. Cumpston, John C. WigginsIIIIII, Sean Mlodzinski, Jacob Moyer & Brandon K. Wills. (2018) Update on Current Treatment of Acute Opioid Overdose. Current Treatment Options in Psychiatry 5:3, pages 301-312.
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Ventricular fibrillation due to overdose of loperamide, the “poor man’s methadone”

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Ventricular fibrillation due to overdose of loperamide, the “poor man’s methadone”

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