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Research Article

The Retinoid Signaling System — A Target in Dioxin Toxicity

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Pages 211-232 | Published online: 29 Sep 2008

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Javier Esteban, Ismael Sánchez-Pérez, Gerd Hamscher, Hanna M. Miettinen, Merja Korkalainen, Matti Viluksela, Raimo Pohjanvirta & Helen Håkansson. (2021) Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice. Reproductive Toxicology 101, pages 33-49.
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Elise Grignard, Helen Håkansson & Sharon Munn. (2020) Regulatory needs and activities to address the retinoid system in the context of endocrine disruption: The European viewpoint. Reproductive Toxicology 93, pages 250-258.
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Hugues Jacobs, Christine Dennefeld, Betty Féret, Matti Viluksela, Helen Håkansson, Manuel Mark & Norbert B. Ghyselinck. (2011) Retinoic Acid Drives Aryl Hydrocarbon Receptor Expression and Is Instrumental to Dioxin-Induced Toxicity during Palate Development. Environmental Health Perspectives 119:11, pages 1590-1595.
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Pi Hoegberg, Carsten K. Schmidt, Nick Fletcher, Charlotte B. Nilsson, Christina Trossvik, A. Gerlienke Schuur, Abraham Brouwer, Heinz Nau, Norbert B. Ghyselinck, Pierre Chambon & Helen Håkansson. (2005) Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms. Chemico-Biological Interactions 156:1, pages 25-39.
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Nick Fletcher, Norbert Giese, Carsten Schmidt, Natalia Stern, P. Monica Lind, Matti Viluksela, Jouni T. Tuomisto, Jouko Tuomisto, Heinz Nau & Helen Håkansson. (2005) Altered Retinoid Metabolism in Female Long-Evans and Han/Wistar Rats following Long-Term 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Treatment. Toxicological Sciences 86:2, pages 264-272.
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Noriko Nishimura, Junzo Yonemoto, Yuichi Miyabara, Yoshiaki Fujii-Kuriyama & Chiharu Tohyama. (2004) Altered thyroxin and retinoid metabolic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in aryl hydrocarbon receptor-null mice. Archives of Toxicology 79:5, pages 260-267.
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Hayashida Yasufumi, Toshiyuki Kawamura, Ryota Hori-e & Ichiro Yamashita. (2004) Retionic Acid and Its Receptors Are Required for Expression of Aryl Hydrocarbon Receptor mRNA and Embryonic Development of Blood Vessel and Bone in the Medaka Fish, Oryzias latipes. Zoological Science 21:5, pages 541-551.
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Ann-Kathrine Alveblom, Lars Rylander, Olof Johnell & Lars Hagmar. (2003) Incidence of hospitalized osteoporotic fractures in cohorts with high dietary intake of persistent organochlorine compounds. International Archives of Occupational and Environmental Health 76:3, pages 246-248.
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Pi Hoegberg, Carsten K Schmidt, Heinz Nau, A Catharine Ross, Reza Zolfaghari, Nicholas Fletcher, Christina Trossvik, Charlotte B Nilsson & Helen Håkansson. (2003) 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces lecithin: retinol acyltransferase transcription in the rat kidney. Chemico-Biological Interactions 145:1, pages 1-16.
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