Advanced search
Publication Cover
AJOB Neuroscience Volume 3, 2012 - Issue 2
Submit an article Journal homepage
194
Views
18
CrossRef citations to date
0
Altmetric
Target Article

Intracranial Stem Cell-Based Transplantation: Reconsidering the Ethics of Phase 1 Clinical Trials in Light of Irreversible Interventions in the Brain

Pascale Hess Novel Tech Ethics, Dalhousie University
Pages 3-13 | Published online: 18 Apr 2012

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (10)

Frederic Gilbert, Alexander R. Harris, Susan Dodds & Robert M. I. Kapsa. (2015) Is a ‘Last Chance’ Treatment Possible After an Irreversible Brain Intervention?. AJOB Neuroscience 6:2, pages W1-W2.
Read now
Pascale Hess. (2014) The Ethical Dilemmas of Experimental Invasive Brain Technologies. AJOB Neuroscience 5:3, pages 18-20.
Read now
Frederic Gilbert, Alexander R. Harris & Robert M. I. Kapsa. (2014) Controlling Brain Cells With Light: Ethical Considerations for Optogenetic Clinical Trials. AJOB Neuroscience 5:3, pages 3-11.
Read now
Dolan Sondhi, Jonathan B Rosenberg, Benjamin G Van de Graaf, Stephen M Kaminsky & Ronald G Crystal. (2013) Advances in the treatment of neuronal ceroid lipofuscinosis. Expert Opinion on Orphan Drugs 1:12, pages 951-975.
Read now
Mark Yarborough, Teresa Tempkin, Jan Nolta & Nanette Joyce. (2012) The Complex Ethics of First in Human Stem Cell Clinical Trials. AJOB Neuroscience 3:2, pages 14-16.
Read now
AudreyR. Chapman. (2012) Improving Subject Safety in High-Risk Phase I Trials With Stem Cell-Based Candidate Therapies. AJOB Neuroscience 3:2, pages 18-20.
Read now
PhilipH. Schwartz. (2012) The Nature of the Pediatric Brain and Its Associated Diseases Precludes Adult Surrogates for Testing Intracranial Stem Cell-Based Transplantation Strategies. AJOB Neuroscience 3:2, pages 16-18.
Read now
Eric Racine. (2012) Are the Conditions in Place for the Development of a Strong and Interdisciplinary Neuroethics?. AJOB Neuroscience 3:2, pages 1-2.
Read now
Gaia Barazzetti, SamiaA. Hurst & Alex Mauron. (2012) Clinically Driven Safety Benchmarks. AJOB Neuroscience 3:2, pages 22-23.
Read now
Frederic Gilbert, AlexanderR. Harris & RobertM. I. Kapsa. (2012) Efficacy Testing as a Primary Purpose of Phase 1 Clinical Trials: Is it Applicable to First-in-Human Bionics and Optogenetics Trials?. AJOB Neuroscience 3:2, pages 20-22.
Read now

Articles from other publishers (7)

ERAN KLEIN, BETTS PETERS & MATT HIGGER. (2018) Ethical Considerations in Ending Exploratory Brain–Computer Interface Research Studies in Locked-in Syndrome. Cambridge Quarterly of Healthcare Ethics 27:4, pages 660-674.
Crossref
John D. Banja. 2017. Safety, Ethics and Regulations. Safety, Ethics and Regulations 155 171 .
Michelle GJL Habets, Johannes JM van Delden, Sophie L Niemansburg, Harold L Atkins & Annelien L Bredenoord. (2016) One Size Fits All?: Ethical Considerations for Examining Efficacy in First-in-Human Pluripotent Stem Cell Studies. Molecular Therapy 24:12, pages 2039-2042.
Crossref
Nut Koonrungsesomboon, Junjira Laothavorn & Juntra Karbwang. (2016) Ethical considerations and challenges in first-in-human research. Translational Research 177, pages 6-18.
Crossref
John Dennis Banja. (2015) Ethical Considerations in Stem Cell Research on Neurologic and Orthopedic Conditions. PM&R 7, pages S66-S75.
Crossref
Heiner Fangerau & Norbert W. Paul. 2015. Handbook of Neuroethics. Handbook of Neuroethics 845 858 .
Michelle GJL Habets, Johannes JM van Delden & Annelien L Bredenoord. (2014) The social value of clinical research. BMC Medical Ethics 15:1.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.